TESTmBANKmPATHOPHYSIOLOGY mTHEmBIOLOGICmBASISmFORmDISEASEmINmADULTSmANDmCHILDRENm8th mEdition mKathryn mL.m
McCance, mSuemE.mHuether
TEST BANK m
PATHOPHYSIOLOGY
THE BIOLOGIC BASIS FOR DISEASE IN ADULTS AND C HILDREN
M M M M M M M M
8th Edition
m
Kathryn L. McCance, Sue E. Huether
m m m m m
TESTmBANKmPATHOPHYSIOLOGY mTHEmBIOLOGICmBASISmFORmDISEASEmINmADULTSmANDmCHILDRENm8th mEdition mKathryn mL.m
McCance, mSuemE.mHuether
, m 2
Contents
Chapterm01:mCellularmBiology ............................................................................................................... 4
Chapterm02:mAlteredmCellularmandmTissue mBiology:mEnvironmentalmAgents ............................................ 18
Chapterm03:mThe mCellularmEnvironment:mFluidsmandmElectrolytes,mAcidsmandmBases ............................... 31
Chapterm04:mGenesmandmGeneticmDiseases.......................................................................................... 44
Chapterm05:mGenes,mEnvironment-Lifestyle,mandmCommonmDiseases .................................................... 55
Chapterm06:mEpigeneticsmandmDisease ................................................................................................ 63
Chapterm07:mInnatemImmunity:mInflammationmandmWoundmHealing...................................................... 68
Chapterm08:mAdaptivemImmunity........................................................................................................ 83
Chapterm09:mAlterationsminmImmunitymandmInflammation..................................................................... 95
Chapterm10:mInfection...................................................................................................................... 108
Chapterm11:mStressmandmDisease ...................................................................................................... 117
Chapterm12:mCancermBiology ............................................................................................................ 124
Chapterm13:mCancermEpidemiology ................................................................................................... 137
Chapterm14:mCancerminmChildren....................................................................................................... 143
Chapterm15:mStructuremandmFunctionmofmthemNeurologicmSystem........................................................ 148
Chapterm16:mPain,mTemperaturemRegulation,mSleep,mandmSensorymFunction ........................................ 159
Chapterm17:mAlterationsminmCognitivemSystems,mCerebralmHemodynamics, mandmMotormFunction .......... 174
Chapterm18:mDisordersmofmthe mCentralmandmPeripheralmNervousmSystemsmandmthe mNeuromuscularmJunction
. ...................................................................................................................................................188
Chapterm19:mNeurobiologymofmSchizophrenia, mMoodmDisorders,mandmAnxietymDisorders ...................... 199
Chapterm20:mAlterationsmofmNeurologicmFunctionminmChildren............................................................. 206
Chapterm21:mMechanismsmof mHormonalmRegulation........................................................................... 213
Chapterm22:mAlterationsmofmHormonalmRegulation............................................................................. 222
Chapterm23:mObesitymandmDisordersmofmNutrition.............................................................................. 234
Chapterm24:mStructuremandmFunctionmofmthe mReproductivemSystems................................................... 239
Chapterm25:mAlterationsmofmthemFemalemReproductivemSystem .......................................................... 249
Chapterm26:mAlterationsmofmthemMalemReproductivemSystem.............................................................. 259
Chapterm27:mSexuallymTransmittedmInfections ................................................................................... 265
Chapterm28:mStructuremandmFunctionmofmthemHematologicmSystem ..................................................... 273
Chapterm29:mAlterationsmofmErythrocytes,mPlatelets,mandmHemostaticmFunction................................... 283
TESTmBANKmPATHOPHYSIOLOGY mTHEmBIOLOGICmBASISmFORmDISEASEmINmADULTSmANDmCHILDRENm8th mEdition mKathryn mL.m
McCance, mSuemE.mHuether
, m 3
Chapterm30:mAlterationsmofmLeukocytemandmLymphoidmFunction......................................................... 293
Chapterm31:mAlterationsmofmHematologicmFunctionminmChildren.......................................................... 300
Chapterm32:mStructuremandmFunctionmofmthe mCardiovascularmandmLymphaticmSystems ......................... 311
Chapterm33:mAlterationsmofmCardiovascularmFunction......................................................................... 324
Chapterm34:mAlterationsmofmCardiovascularmFunctionminmChildren ....................................................... 338
Chapterm35:mStructuremandmFunctionmofmthe mPulmonarymSystem........................................................ 346
Chapterm36:mAlterationsmofmPulmonarymFunction............................................................................... 356
Chapterm37:mAlterationsmofmPulmonarymFunctionminmChildren............................................................. 373
Chapterm38:mStructuremandmFunctionmofmthemRenalmandmUrologicmSystems.......................................... 381
Chapterm39:mAlterationsmofmRenalmandmUrinarymTractmFunction .......................................................... 391
Chapterm40:mAlterationsmofmRenalmandmUrinarymTractmFunctionminmChildren ........................................ 401
Chapterm41:mStructuremandmFunctionmofmthe mDigestivemSystem .......................................................... 409
Chapterm42:mAlterationsmofmDigestive mFunction................................................................................. 421
Chapterm43:mAlterationsmofmDigestive mFunctionminmChildren ............................................................... 432
Chapterm44:mStructuremandmFunctionmofmthe mMusculoskeletalmSystem................................................ 441
Chapterm45:mAlterationsmofmMusculoskeletalmFunction....................................................................... 453
Chapterm46:mAlterationsmofmMusculoskeletalmFunctionminmChildren..................................................... 466
Chapterm47:mStructure,mFunction,mandmDisordersmof mthe mIntegument ................................................. 475
Chapterm48:mAlterationsmofmthemIntegumentminmChildren ................................................................... 486
Chapterm49:mShock,mMultiplemOrganmDysfunctionmSyndrome,mandmBurnsminmAdults ............................. 494
Chapterm50:mShock,mMultiplemOrganmDysfunctionmSyndrome,mandmBurnsminmChildren .......................... 502
TESTmBANKmPATHOPHYSIOLOGY mTHEmBIOLOGICmBASISmFORmDISEASEmINmADULTSmANDmCHILDRENm8th mEdition mKathryn mL.m
McCance, mSuemE.mHuether
, TestmBankm-mPathophysiology:mThe mBiologicmBasismformDisease minmAdultsmandmChildrenm(8th) m m m 4
Chapter 01: Cellular Biology
m m m
MULTIPLEmCHOICE
1. Whichmstatement mbest mdescribesmthemcellularmfunctionmof mmetabolicmabsorption?
a. Cellsmcanmproducemproteins.
b. Cellsmcanmsecretemdigestivemenzymes.
c. Cellsmcanmtakeminmand musemnutrients.
d. Cellsmcanmsynthesizemfats.
ANS:m C
Inmmetabolicmabsorption,mallmcellsmtakeminmand musemnutrientsmand mothermsubstancesmfrommtheirmsurroun
dings.mThemremainingmoptionsmaremnot minclusiveminmtheirmdescriptionsmof mcellularmmetabolicmabsorption
.
PTS:m m 1 DIF: CognitivemLevel:mRemembering
2. Wheremismmost mof mamcell’smgeneticminformation,mincludingmRNA mand mDNA,mcontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Lysosome
ANS:m C
Themnucleusmcontainsmthemnucleolus,mamsmallmdensemstructuremcomposed mlargelymof mRNA,mmost mo
f mthemcellularmDNA,mand mthemDNA-
bindingmproteins,msuchmasmthemhistones,mwhichmregulatemitsmactivity.mThemmitochondriamarem respo
nsiblemformcellularmrespirationmand menergymproduction.
Ribosomes’mchief mfunctionmismtomprovidemsitesmformcellularmproteinmsynthesis.mLysosomesmfunctio
nmasmthemintracellularmdigestivemsystem.
PTS:m m 1 DIF: CognitivemLevel:mRemembering
3. Whichmcomponent mof mthemcellmproducesmhydrogenmperoxidem(H2 O2 )mbymusingmoxygenmtomremo
vemhydrogenmatomsmfrommspecificmsubstratesminmanmoxidativemreaction?
a. Lysosomes
b. Peroxisomes
c. Ribosomes
d. Endosome
ANS:m B
TESTmBANKmPATHOPHYSIOLOGY mTHEmBIOLOGICmBASISmFORmDISEASEmINmADULTSmANDmCHILDRENm8th mEdition mKathryn mL.m
McCance, mSuemE.mHuether
McCance, mSuemE.mHuether
TEST BANK m
PATHOPHYSIOLOGY
THE BIOLOGIC BASIS FOR DISEASE IN ADULTS AND C HILDREN
M M M M M M M M
8th Edition
m
Kathryn L. McCance, Sue E. Huether
m m m m m
TESTmBANKmPATHOPHYSIOLOGY mTHEmBIOLOGICmBASISmFORmDISEASEmINmADULTSmANDmCHILDRENm8th mEdition mKathryn mL.m
McCance, mSuemE.mHuether
, m 2
Contents
Chapterm01:mCellularmBiology ............................................................................................................... 4
Chapterm02:mAlteredmCellularmandmTissue mBiology:mEnvironmentalmAgents ............................................ 18
Chapterm03:mThe mCellularmEnvironment:mFluidsmandmElectrolytes,mAcidsmandmBases ............................... 31
Chapterm04:mGenesmandmGeneticmDiseases.......................................................................................... 44
Chapterm05:mGenes,mEnvironment-Lifestyle,mandmCommonmDiseases .................................................... 55
Chapterm06:mEpigeneticsmandmDisease ................................................................................................ 63
Chapterm07:mInnatemImmunity:mInflammationmandmWoundmHealing...................................................... 68
Chapterm08:mAdaptivemImmunity........................................................................................................ 83
Chapterm09:mAlterationsminmImmunitymandmInflammation..................................................................... 95
Chapterm10:mInfection...................................................................................................................... 108
Chapterm11:mStressmandmDisease ...................................................................................................... 117
Chapterm12:mCancermBiology ............................................................................................................ 124
Chapterm13:mCancermEpidemiology ................................................................................................... 137
Chapterm14:mCancerminmChildren....................................................................................................... 143
Chapterm15:mStructuremandmFunctionmofmthemNeurologicmSystem........................................................ 148
Chapterm16:mPain,mTemperaturemRegulation,mSleep,mandmSensorymFunction ........................................ 159
Chapterm17:mAlterationsminmCognitivemSystems,mCerebralmHemodynamics, mandmMotormFunction .......... 174
Chapterm18:mDisordersmofmthe mCentralmandmPeripheralmNervousmSystemsmandmthe mNeuromuscularmJunction
. ...................................................................................................................................................188
Chapterm19:mNeurobiologymofmSchizophrenia, mMoodmDisorders,mandmAnxietymDisorders ...................... 199
Chapterm20:mAlterationsmofmNeurologicmFunctionminmChildren............................................................. 206
Chapterm21:mMechanismsmof mHormonalmRegulation........................................................................... 213
Chapterm22:mAlterationsmofmHormonalmRegulation............................................................................. 222
Chapterm23:mObesitymandmDisordersmofmNutrition.............................................................................. 234
Chapterm24:mStructuremandmFunctionmofmthe mReproductivemSystems................................................... 239
Chapterm25:mAlterationsmofmthemFemalemReproductivemSystem .......................................................... 249
Chapterm26:mAlterationsmofmthemMalemReproductivemSystem.............................................................. 259
Chapterm27:mSexuallymTransmittedmInfections ................................................................................... 265
Chapterm28:mStructuremandmFunctionmofmthemHematologicmSystem ..................................................... 273
Chapterm29:mAlterationsmofmErythrocytes,mPlatelets,mandmHemostaticmFunction................................... 283
TESTmBANKmPATHOPHYSIOLOGY mTHEmBIOLOGICmBASISmFORmDISEASEmINmADULTSmANDmCHILDRENm8th mEdition mKathryn mL.m
McCance, mSuemE.mHuether
, m 3
Chapterm30:mAlterationsmofmLeukocytemandmLymphoidmFunction......................................................... 293
Chapterm31:mAlterationsmofmHematologicmFunctionminmChildren.......................................................... 300
Chapterm32:mStructuremandmFunctionmofmthe mCardiovascularmandmLymphaticmSystems ......................... 311
Chapterm33:mAlterationsmofmCardiovascularmFunction......................................................................... 324
Chapterm34:mAlterationsmofmCardiovascularmFunctionminmChildren ....................................................... 338
Chapterm35:mStructuremandmFunctionmofmthe mPulmonarymSystem........................................................ 346
Chapterm36:mAlterationsmofmPulmonarymFunction............................................................................... 356
Chapterm37:mAlterationsmofmPulmonarymFunctionminmChildren............................................................. 373
Chapterm38:mStructuremandmFunctionmofmthemRenalmandmUrologicmSystems.......................................... 381
Chapterm39:mAlterationsmofmRenalmandmUrinarymTractmFunction .......................................................... 391
Chapterm40:mAlterationsmofmRenalmandmUrinarymTractmFunctionminmChildren ........................................ 401
Chapterm41:mStructuremandmFunctionmofmthe mDigestivemSystem .......................................................... 409
Chapterm42:mAlterationsmofmDigestive mFunction................................................................................. 421
Chapterm43:mAlterationsmofmDigestive mFunctionminmChildren ............................................................... 432
Chapterm44:mStructuremandmFunctionmofmthe mMusculoskeletalmSystem................................................ 441
Chapterm45:mAlterationsmofmMusculoskeletalmFunction....................................................................... 453
Chapterm46:mAlterationsmofmMusculoskeletalmFunctionminmChildren..................................................... 466
Chapterm47:mStructure,mFunction,mandmDisordersmof mthe mIntegument ................................................. 475
Chapterm48:mAlterationsmofmthemIntegumentminmChildren ................................................................... 486
Chapterm49:mShock,mMultiplemOrganmDysfunctionmSyndrome,mandmBurnsminmAdults ............................. 494
Chapterm50:mShock,mMultiplemOrganmDysfunctionmSyndrome,mandmBurnsminmChildren .......................... 502
TESTmBANKmPATHOPHYSIOLOGY mTHEmBIOLOGICmBASISmFORmDISEASEmINmADULTSmANDmCHILDRENm8th mEdition mKathryn mL.m
McCance, mSuemE.mHuether
, TestmBankm-mPathophysiology:mThe mBiologicmBasismformDisease minmAdultsmandmChildrenm(8th) m m m 4
Chapter 01: Cellular Biology
m m m
MULTIPLEmCHOICE
1. Whichmstatement mbest mdescribesmthemcellularmfunctionmof mmetabolicmabsorption?
a. Cellsmcanmproducemproteins.
b. Cellsmcanmsecretemdigestivemenzymes.
c. Cellsmcanmtakeminmand musemnutrients.
d. Cellsmcanmsynthesizemfats.
ANS:m C
Inmmetabolicmabsorption,mallmcellsmtakeminmand musemnutrientsmand mothermsubstancesmfrommtheirmsurroun
dings.mThemremainingmoptionsmaremnot minclusiveminmtheirmdescriptionsmof mcellularmmetabolicmabsorption
.
PTS:m m 1 DIF: CognitivemLevel:mRemembering
2. Wheremismmost mof mamcell’smgeneticminformation,mincludingmRNA mand mDNA,mcontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Lysosome
ANS:m C
Themnucleusmcontainsmthemnucleolus,mamsmallmdensemstructuremcomposed mlargelymof mRNA,mmost mo
f mthemcellularmDNA,mand mthemDNA-
bindingmproteins,msuchmasmthemhistones,mwhichmregulatemitsmactivity.mThemmitochondriamarem respo
nsiblemformcellularmrespirationmand menergymproduction.
Ribosomes’mchief mfunctionmismtomprovidemsitesmformcellularmproteinmsynthesis.mLysosomesmfunctio
nmasmthemintracellularmdigestivemsystem.
PTS:m m 1 DIF: CognitivemLevel:mRemembering
3. Whichmcomponent mof mthemcellmproducesmhydrogenmperoxidem(H2 O2 )mbymusingmoxygenmtomremo
vemhydrogenmatomsmfrommspecificmsubstratesminmanmoxidativemreaction?
a. Lysosomes
b. Peroxisomes
c. Ribosomes
d. Endosome
ANS:m B
TESTmBANKmPATHOPHYSIOLOGY mTHEmBIOLOGICmBASISmFORmDISEASEmINmADULTSmANDmCHILDRENm8th mEdition mKathryn mL.m
McCance, mSuemE.mHuether
