NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
d d d d d d
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
d d d d d d d d
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
d d d d d d d d
T UPDATE 2022
d d
Chapter 18. Drugs Affecting the Endocrine System: Pancreatic Hormones and Antidiabetic
d d d d d d d d d d d
Drugs
• Patients with cystic fibrosis are often prescribed enzyme replacement for pancreatic secr
d d d d d d d d d d d
etions. Each replacement drug has lipase, protease, and amylase components, but the dru
d d d d d d d d d d d d
g is prescribed in units of:
d d d d d
a. Lipase
b. Protease
c. Amylase
d. Pancreatin
• Brands of pancreatic enzyme replacement drugs are:
d d d d d d
a. Bioequivalent
b. About the same in cost per unit of lipase across brands
d d d d d d d d d d
c. Able to be interchanged between generic and brand-name products to reduce cost
d d d d d d d d d d d
d. None of the above d d d
• When given subcutaneously, how long until neutral protamine Hagedorn insulin begins to tak
d d d d d d d d d d d d
e effect (onsetof action) after administration?
d d d d d d
a. 15 to 30 minutes d d d
b. 60 to 90 minutes d d d
c. 3 to 4 hours d d d
d. 6 to 8 hours d d d
• Hypoglycemia can result from the action of either insulin or an oral hypoglycemic. Signs and
d d d d d d d d d d d d d d d
NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
d d d d d d
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
d d d d d d d d
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
d d d d d d d d
T UPDATE 2022
d d
,NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
d d d d d d
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
d d d d d d d d
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
d d d d d d d d
T UPDATE 2022
d d
symptoms ofhypoglycemia include: d d d
a. “Fruity” breath odor and rapid respiration d d d d d
b. Diarrhea, abdominal pain, weight loss, and hyper d d d d d d
tensionc. Dizziness, confusion, diaphoresis, and tac
d d d d d d
hycardia
d. Easy bruising, palpitations, cardiac dysrhythmias, and coma
d d d d d d d
• Nonselective beta blockers and alcohol create serious drug interactions with insulin because they:
d d d d d d d d d d d d
a. Increase blood glucose levels d d d
b. Produce unexplained diaphoresis d d
c. Interfere with the ability of the body to metabolize d d d d d d d d d
glucosed. Mask the signs and symptoms of altered gluc
d d d d d d d d d
ose levels d
• Lispro is an insulin analogue produced by recombinant DNA technology. W
d d d d d d d d d d
hich of thefollowing statements about this form of insulin is NOT true?
d d d d d d d d d d d d
a. Optimal time of preprandial injection is 15 minutes. d d d d d d d
b. Duration of action is increased when the dose is increased.
d d d d d d d d d
c. It is compatible with neutral protamine Hagedorn insulin.
d d d d d d d
d. It has no pronounced peak.
d d d d
• The decision may be made to switch from twice daily neutral protamine Haged
d d d d d d d d d d d d
orn (NPH)insulin to insulin glargine to improve glycemia control throughout t
d d d d d d d d d d d
he day. If this is done:
d d d d d
NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
d d d d d d
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
d d d d d d d d
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
d d d d d d d d
T UPDATE 2022
d d
,NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
d d d d d d
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
d d d d d d d d
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
d d d d d d d d
T UPDATE 2022
d d
a. The initial dose of glargine is reduced by 20% to avoid hypoglycemia.
d d d d d d d d d d d
b. The initial dose of glargine is 2 to 10 units per day.
d d d d d d d d d d d
c. Patients who have been on high doses of NPH will need tests for insulin antibodies.
d d d d d d d d d d d d d d
d. Obese patients may require more than 100 units per day.
d d d d d d d d d
• When blood glucose levels are difficult to control in type 2 diabetes some form of i
d d d d d d d d d d d d d d d
nsulin maybe added to the treatment regimen to control blood glucose and limit co
d d d d d d d d d d d d d d
mplication risks. d
Which ofthe following statements is accurate based on research?
d d d d d d d d
a. Premixed insulin analogues are better at lowering HbA1C and have le
d d d d d d d d d d
ss risk forhypoglycemia.
d d d
b. Premixed insulin analogues and the newer premixed insulins are associated
d d d d d d d d d d
with moreweight gain than the oral antidiabetic agents.
d d d d d d d d
c. Newer premixed insulins are better at lowering HbA1C and postprandi
d d d d d d d d d
al glucoselevels than long-acting insulins.
d d d d d
d. Patients who are not controlled on oral agents and have postprandial hype
d d d d d d d d d d d
rglycemiacan have neutral protamine Hagedorn insulin added at bedtime.
d d d d d d d d d
• Metformin is a primary choice of drug to treat hyperglycemia in type 2 diabetes because it:
d d d d d d d d d d d d d d d
a. Substitutes for insulin usually secreted by the p d d d d d d d
ancreasb. Decreases glycogenolysis by the liver
d d d d d d
c. Increasesdthedreleasedofdinsulindfromdbetadcells
d. Decreasesdperipheraldglucosedutilization
• Prior to prescribing metformin, the provider should:
d d d d d d
NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
d d d d d d
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
d d d d d d d d
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
d d d d d d d d
T UPDATE 2022
d d
, NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
d d d d d d
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
d d d d d d d d
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
d d d d d d d d
T UPDATE 2022 d d
a. Draw a serum creatinine to assess renal function
d d d d d d d
b. Try the patient on insulin
d d d d
c. Tell the patient to increase iodine intake
d d d d d d
d. Have the patient stop taking any sulfonylurea to avoid dangerous drug interactions
d d d d d d d d d d d
• The action of “gliptins” is different from other antidiabetic agents because they:
d d d d d d d d d d d
a. Have a low risk for hypoglycemia
d d d d d
b. Are not associated with weight gain
d d d d d
c. Close ATP-dependent potassium channels in the beta cell
d d d d d d d
d. Act on the incretin system to indirectly increase insulin production
d d d d d d d d d
• Sitagliptin has been approved for:
d d d d
a. Monotherapy in once-daily doses d d d
b. Combination therapy with metformin d d d
c. Both 1 and 2
d d d d
d. Neither 1 nor 2 d d d
• GLP-1 agonists: d
a. Directly bind to a receptor in the pancreatic beta cell
d d d d d d d d d
b. Have been approved for monotherapy
d d d d
c. Speed gastric emptying to decrease appetite
d d d d d
d. Can be given orally once daily
d d d d d
• Avoid concurrent administration of exenatide with which of the following drugs?
d d d d d d d d d d
a. Digoxin
NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
d d d d d d
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
d d d d d d d d
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
d d d d d d d d
T UPDATE 2022 d d
d d d d d d
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
d d d d d d d d
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
d d d d d d d d
T UPDATE 2022
d d
Chapter 18. Drugs Affecting the Endocrine System: Pancreatic Hormones and Antidiabetic
d d d d d d d d d d d
Drugs
• Patients with cystic fibrosis are often prescribed enzyme replacement for pancreatic secr
d d d d d d d d d d d
etions. Each replacement drug has lipase, protease, and amylase components, but the dru
d d d d d d d d d d d d
g is prescribed in units of:
d d d d d
a. Lipase
b. Protease
c. Amylase
d. Pancreatin
• Brands of pancreatic enzyme replacement drugs are:
d d d d d d
a. Bioequivalent
b. About the same in cost per unit of lipase across brands
d d d d d d d d d d
c. Able to be interchanged between generic and brand-name products to reduce cost
d d d d d d d d d d d
d. None of the above d d d
• When given subcutaneously, how long until neutral protamine Hagedorn insulin begins to tak
d d d d d d d d d d d d
e effect (onsetof action) after administration?
d d d d d d
a. 15 to 30 minutes d d d
b. 60 to 90 minutes d d d
c. 3 to 4 hours d d d
d. 6 to 8 hours d d d
• Hypoglycemia can result from the action of either insulin or an oral hypoglycemic. Signs and
d d d d d d d d d d d d d d d
NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
d d d d d d
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
d d d d d d d d
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
d d d d d d d d
T UPDATE 2022
d d
,NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
d d d d d d
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
d d d d d d d d
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
d d d d d d d d
T UPDATE 2022
d d
symptoms ofhypoglycemia include: d d d
a. “Fruity” breath odor and rapid respiration d d d d d
b. Diarrhea, abdominal pain, weight loss, and hyper d d d d d d
tensionc. Dizziness, confusion, diaphoresis, and tac
d d d d d d
hycardia
d. Easy bruising, palpitations, cardiac dysrhythmias, and coma
d d d d d d d
• Nonselective beta blockers and alcohol create serious drug interactions with insulin because they:
d d d d d d d d d d d d
a. Increase blood glucose levels d d d
b. Produce unexplained diaphoresis d d
c. Interfere with the ability of the body to metabolize d d d d d d d d d
glucosed. Mask the signs and symptoms of altered gluc
d d d d d d d d d
ose levels d
• Lispro is an insulin analogue produced by recombinant DNA technology. W
d d d d d d d d d d
hich of thefollowing statements about this form of insulin is NOT true?
d d d d d d d d d d d d
a. Optimal time of preprandial injection is 15 minutes. d d d d d d d
b. Duration of action is increased when the dose is increased.
d d d d d d d d d
c. It is compatible with neutral protamine Hagedorn insulin.
d d d d d d d
d. It has no pronounced peak.
d d d d
• The decision may be made to switch from twice daily neutral protamine Haged
d d d d d d d d d d d d
orn (NPH)insulin to insulin glargine to improve glycemia control throughout t
d d d d d d d d d d d
he day. If this is done:
d d d d d
NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
d d d d d d
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
d d d d d d d d
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
d d d d d d d d
T UPDATE 2022
d d
,NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
d d d d d d
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
d d d d d d d d
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
d d d d d d d d
T UPDATE 2022
d d
a. The initial dose of glargine is reduced by 20% to avoid hypoglycemia.
d d d d d d d d d d d
b. The initial dose of glargine is 2 to 10 units per day.
d d d d d d d d d d d
c. Patients who have been on high doses of NPH will need tests for insulin antibodies.
d d d d d d d d d d d d d d
d. Obese patients may require more than 100 units per day.
d d d d d d d d d
• When blood glucose levels are difficult to control in type 2 diabetes some form of i
d d d d d d d d d d d d d d d
nsulin maybe added to the treatment regimen to control blood glucose and limit co
d d d d d d d d d d d d d d
mplication risks. d
Which ofthe following statements is accurate based on research?
d d d d d d d d
a. Premixed insulin analogues are better at lowering HbA1C and have le
d d d d d d d d d d
ss risk forhypoglycemia.
d d d
b. Premixed insulin analogues and the newer premixed insulins are associated
d d d d d d d d d d
with moreweight gain than the oral antidiabetic agents.
d d d d d d d d
c. Newer premixed insulins are better at lowering HbA1C and postprandi
d d d d d d d d d
al glucoselevels than long-acting insulins.
d d d d d
d. Patients who are not controlled on oral agents and have postprandial hype
d d d d d d d d d d d
rglycemiacan have neutral protamine Hagedorn insulin added at bedtime.
d d d d d d d d d
• Metformin is a primary choice of drug to treat hyperglycemia in type 2 diabetes because it:
d d d d d d d d d d d d d d d
a. Substitutes for insulin usually secreted by the p d d d d d d d
ancreasb. Decreases glycogenolysis by the liver
d d d d d d
c. Increasesdthedreleasedofdinsulindfromdbetadcells
d. Decreasesdperipheraldglucosedutilization
• Prior to prescribing metformin, the provider should:
d d d d d d
NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
d d d d d d
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
d d d d d d d d
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
d d d d d d d d
T UPDATE 2022
d d
, NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
d d d d d d
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
d d d d d d d d
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
d d d d d d d d
T UPDATE 2022 d d
a. Draw a serum creatinine to assess renal function
d d d d d d d
b. Try the patient on insulin
d d d d
c. Tell the patient to increase iodine intake
d d d d d d
d. Have the patient stop taking any sulfonylurea to avoid dangerous drug interactions
d d d d d d d d d d d
• The action of “gliptins” is different from other antidiabetic agents because they:
d d d d d d d d d d d
a. Have a low risk for hypoglycemia
d d d d d
b. Are not associated with weight gain
d d d d d
c. Close ATP-dependent potassium channels in the beta cell
d d d d d d d
d. Act on the incretin system to indirectly increase insulin production
d d d d d d d d d
• Sitagliptin has been approved for:
d d d d
a. Monotherapy in once-daily doses d d d
b. Combination therapy with metformin d d d
c. Both 1 and 2
d d d d
d. Neither 1 nor 2 d d d
• GLP-1 agonists: d
a. Directly bind to a receptor in the pancreatic beta cell
d d d d d d d d d
b. Have been approved for monotherapy
d d d d
c. Speed gastric emptying to decrease appetite
d d d d d
d. Can be given orally once daily
d d d d d
• Avoid concurrent administration of exenatide with which of the following drugs?
d d d d d d d d d d
a. Digoxin
NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
d d d d d d
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
d d d d d d d d
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
d d d d d d d d
T UPDATE 2022 d d
