Huether & McCance: Understanding Pathophysiology, 6th Edition
A A A A A A
Chapter 01: Cellular Biology
A A A
MULTIPLEACHOICE
1. AAstudentAisAobservingAaAcellAunderAtheAmicroscope.AItAisAobservedAtoAhaveAsupercoiledADN
AAwithAhistones.AWhichAofAtheAfollowingAwouldAalsoAbeAobservedAbyAtheAstudent?
a. AAsingleAcircularAchromosome
b. AAnucleus
c. Free-floatingAnuclearAmaterial
d. NoAorganelles
ANS:A B
TheAcellAdescribedAisAaAeukaryoticAcell,AsoAitAhasAhistonesAandAaAsupercoiledADNAAwithinAitsA
nucleus;Athus,AtheAnucleusAshouldAbeAobserved.AAAsingleAcircularAchromosomeAcalledAaAproka
ryoteAcontainsAfree-floatingAnuclearAmaterialAbutAhasAnoAorganelles.
REF:A p.A2
2. AAnurseAisAinstructingAtheAstaffAaboutAcellularAfunctions.AWhichAcellularAfunctionAisAtheAnurs
eAdescribingAwhenAanAisolatedAcellAabsorbsAoxygenAandAusesAitAtoAtransformAnutrientsAtoAener
gy?
a. MetabolicAabsorption
b. Communication
c. Secretion
d. Respiration
ANS:A D
TheAcell’sAabilityAtoAabsorbAoxygenAisAreferredAtoAasArespirationAwhileAitsAcommunicationAabilityAi
nvolvesAmaintenanceAofAaAsteadyAdynamicAstate,AmetabolicAabsorptionAprovidesAnutrition,AandAsec
retionAallowsAforAtheAsynthesizingAofAnewAsubstances.
REF:A p.A2
3. AAeukaryoticAcellAisAundergoingADNAAreplication.AInAwhichAregionAofAtheAcellAwouldAmostA
ofAtheAgeneticAinformationAbeAcontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. NucleusACytoplasm
ANS:A C
TheAregionAofAtheAcellAthatAcontainsAgeneticAmaterial,AincludingAaAlargeAamountAofAribonucleic
Aacid,AmostAofAtheADNA,AandADNA-
bindingAproteins,AisAtheAnucleolus,AwhichAisAlocatedAwithinAtheAcell’sAnucleus.AMitochondriaAi
sAassociatedAwithAcellularArespiration,AwhileAribosomesAareAinvolvedAwithAproteinAmanufactur
ing.ACytoplasmAisAaAfluidAfillingAthatAisAaAcomponentAofAtheAcell.
REF:A p.A2
,TESTABANKAFORAUNDERSTANDINGAPATHOPHYSIOLOGY
Huether & McCance: Understanding Pathophysiology, 6th Edition
A A A A A A
Chapter 01: Cellular Biology
A A A
4. WhichAofAtheAfollowingAcanAremoveAproteinsAattachedAtoAtheAcell’sAbilayerAbyAdissolvingAt
heAlayerAitself?
a. PeripheralAmembraneAproteins
b. IntegralAmembraneAproteins
c. Glycoproteins
d. CellAadhesionAmolecules
ANS:A B
ProteinsAdirectlyAattachedAtoAtheAmembraneAbilayerAcanAbeAremovedAbyAtheAactionAofAintegralA
membraneAproteinsAthatAdissolveAtheAbilayer.APeripheralAmembraneAproteinsAresideAatAtheAsur
faceAwhileAcellAadhesionAmoleculesAareAonAtheAoutsideAofAtheAmembrane.AGlycoproteinAmarks
AcellsAandAdoesAnotAfloat.
REF:A p.A7
5. WhichAofAtheAfollowingAcanAbindAtoAplasmaAmembraneAreceptors?
a. Oxygen
b. Ribosomes
c. AmphipathicAlipids
d. Ligands
ANS:A D
LigandsAareAtheAonlyAspecificAmoleculesAthatAcanAbindAwithAreceptorsAonAtheAcellAmembrane.
REF:A p.A9
6. AAnurseAisAreviewingAaAreportAfromAaApatientAwithAmetastaticAcancer.AWhatAalternationAinAt
heAextracellularAmatrixAwouldAs uN RrAtTAt hIe AdG
UpApSoAN iagnBo.
siC
sAofM
metastaticAcancer?
a. DecreasedAfibronectin
b. IncreasedAcollagen
c. DecreasedAelastin
d. IncreasedAglycoproteins
ANS:A A
OnlyAaAreducedAamountAofAfibronectinAisAfoundAinAsomeAtypesAofAcancerousAcells,AallowingAth
emAtoAtravelAorAmetastasize.
REF:A p.A10
7. WhichAformAofAcellAcommunicationAisAusedAtoArelateAtoAotherAcellsAinAdirectAphysicalAcontact?
a. CellAjunction
b. GapAjunction
c. Desmosome
d. TightAjunction
ANS:A A
CellAjunctionsAholdAcellsAtogetherAandApermitAmoleculesAtoApassAfromAcellAtoAcell.
GapAjunctionsAallowAforAcellularAcommunicationAbetweenAcells.ANeitherAdesmosomesAnorAtightAjun
ctionsAareAassociatedAwithAcellularAcommunication.
REF:A p.A11
,TESTABANKAFORAUNDERSTANDINGAPATHOPHYSIOLOGY
Huether & McCance: Understanding Pathophysiology, 6th Edition
A A A A A A
Chapter 01: Cellular Biology
A A A
8. PancreaticAbetaAcellsAsecreteAinsulin,AwhichAinhibitsAsecretionAofAglucagonAfromAneighborin
gAalphaAcells.AThisAactionAisAanAexampleAofAwhichAofAtheAfollowingAsignalingAtypes?
a. Paracrine
b. Autocrine
c. Neurohormonal
d. Hormonal
ANS:A A
ParacrineAsignalingAinvolvesAtheAreleaseAofAlocalAchemicalAmediatorsAthatAareAquicklyAtakenAu
p,Adestroyed,AorAimmobilized,AasAinAtheAcaseAofAinsulinAandAtheAinhibitionAofAtheAsecretionAofA
glucagon.ANoneAofAtheAotherAoptionsAinvolveAsignalingAthatAisAassociatedAwithAaAlocalAchemic
alAmediatorAlikeAinsulin.
REF:A p.A12
9. InAcellularAmetabolism,AeachAenzymeAhasAaAhighAaffinityAforAa:
a. solute.
b. substrate.
c. receptor.
d. ribosome.
ANS:A B
EachAenzymeAhasAaAhighAaffinityAforAaAsubstrate,AaAspecificAsubstanceAconvertedAtoAaAproductA
ofAtheAreaction.ACellularAmetabolismAisAnotAdependentAonAanAattractionAbetweenAanAenzymeAa
ndAanyAofAtheAremainingAoptions.
REF:A A p.A16
10. AnAathleteArunsAaAmarathon,AafterAwhichAhisAmusclesAfeelAfatiguedAandAunableAtoAcontract.ATh
eAathleteAasksAtheAnurseAwhyAthisAhappened.ATheAnurse’sAresponseAisAbasedAonAtheAknowledgeA
thatAtheAproblemAisAresultAofAaAdeficiencyAof:
a. GTP
b. AMP
c. ATP
d. GMP
ANS:A C
WhenAATPAisAdeficient,AimpairedAmuscleAcontractionAresults.ANoneAofAtheAotherAoptionsAareAi
nvolvedAinAmuscleAcontraction.
REF:A p.A16
11. WhichAphaseAofAcatabolismAproducesAtheAmostAATP?
a. Digestion
b. Glycolysis
c. Oxidation
d. CitricAacidAcycle
ANS:A D
WhileAsomeAATPAisAproducedAduringAtheAoxidationAandAglycolysisAphases,AmostAofAtheAATPAis
, TESTABANKAFORAUNDERSTANDINGAPATHOPHYSIOLOGY
Huether & McCance: Understanding Pathophysiology, 6th Edition
A A A A A A A
Chapter 01: Cellular Biology
A A A
generatedAduringAtheAcitricAacidAcycle.ADigestionAdoesAnotAproduceAanyAATP.