UNIT I Chapter 1 Impurities in pharmaceutical substances
1. Write principle involved in limit test for chlorides. 2 marks
2. Define Pharmacopoeia with examples. 2 marks
3. What is purity of pharmaceuticals? 2 marks
4. Define limit test. Explain in detail principle, reaction, procedure involved in limit
test for chlorides. 5 marks
5. Write principle, reactions and procedure for limit test of iron. 5 marks
6. Write a note on history of IP. 5 marks
7. What is standard solution in limit test? Explain principle, reaction and procedure of
limit test for heavy metals. 5 marks
8. Explain modified limit test for chlorides and sulfates. 5 marks
9. Write principle, reaction and procedure of limit test for sulfates. 5 marks
10. Write principle, reaction and procedure of limit test for lead. 5 marks
11. Discuss various types and sources of impurities in pharmaceutical substance. 10
marks
12. Enlist sources of impurities. Draw a diagram for Gutzeit apparatus. Explain
principle, reaction and procedure for arsenic limit test. 10 marks
UNIT II Chapter 2 Acids, Bases and Buffers
1. Classify buffers. Give examples of buffers in pharmaceutical system. 2 marks
2. Define acidic buffer and basic buffer with example. 2 marks
3. Explain how buffer maintain physiological acid base balance. 5 marks
4. Define buffers. Write a note on buffer capacity. 5 marks
5. Define buffer. Explain mechanism of buffer action 5 marks
6. Write note on buffer equation and buffer capacity. 5 marks
7. Write a note on physiological acid base balance. 5 marks
8. Define buffers. Write importance of buffer solution / applications in pharmacy. 5
marks
UNIT II Chapter 3 Major extra and intracellular electrolytes:
1. What are electrolytes? 2 marks
2. Give the composition of ORS. 2 marks