NR 507
NR 507 Midterm Exam Study Questions and
Answers Graded A+ 2025
Which client should the nurse practitioner (NP) recognize as most at risk of developing
iron deficiency anemia?
A 25-year-old client who recently became pregnant
A 40-year-old client with a history of peptic ulcers
A 30-year-old client who donates blood every 3 months
A 50-year-old client with congestive heart failure -Correct Answer ✔A 30-year-old client
who donates blood every 3 months
The nurse practitioner (NP) reviews a client's laboratory results. Which laboratory result
best reflects the client's level of iron stores?
Transferrin saturation
Hemoglobin
Serum iron
Serum ferritin
Hematocrit
Total iron-binding capacity -Correct Answer ✔Serum ferritin
The nurse practitioner (NP) is caring for a client with beta thalassemia major. The NP
should anticipate the client will require what? -Correct Answer ✔a bloos transfusion
The nurse practitioner (NP) is counseling a client with iron deficiency anemia about
dietary needs. Which instruction(s) should the NP include? Select all that apply.
Avoid drinking tea or coffee with meals
Consume lean red meat
Increase intake of calcium-rich foods
Consume iron-fortified cereal
Consume vitamin C-rich foods with iron-rich meals -Correct Answer ✔Avoid drinking tea
or coffee with meals
Consume lean red meat
Consume iron-fortified cereal
Consume vitamin C-rich foods with iron-rich meals
A nurse practitioner (NP) is providing pre-conception counseling to a couple, both of
whom are carriers of thalassemia. Which of the following actions should the NP take?
Select all that apply.
Encourage the couple not to conceive.
Refer the couple for genetic counseling.
NR 507
,NR 507
Explain what it means to be a carrier of thalassemia.
Discuss ways to prevent naturally conceiving a child with thalassemia.
Discuss inheritance patterns of thalassemia. -Correct Answer ✔Refer the couple for
genetic counseling.
Explain what it means to be a carrier of thalassemia.
Discuss inheritance patterns of thalassemia.
The nurse practitioner (NP) assesses the client on a follow-up visit after the initiation of
treatment for thalassemia including administration of blood transfusions. What three (3)
assessments should the NP prioritize to evaluate client outcomes? Select 3.
Dietary intake
Developmental milestones
Ferritin level
Hemoglobin level
Energy level -Correct Answer ✔Ferritin level
Hemoglobin level
Energy level
Which of the following clients should the nurse practitioner (NP) recognize as being
most at risk for developing vitamin B-12 deficiency anemia?
An infant who is exclusively breastfed
Middle adult client who eats a high-protein diet
A client who is pregnant
Adult client who had a vertical sleeve gastrectomy -Correct Answer ✔Adult client who
had a vertical sleeve gastrectomy
Mean Corpuscular Hemoglobin Concentration (MCHC) -Correct Answer ✔indicates
hemoglobin concentration in RBCs
Ferritin -Correct Answer ✔total iron stores; low levels indicate iron deficiency
microlytic anemia -Correct Answer ✔small RBC's
-iron deficiency
-thalassemia
Thalassemia beta major treatment -Correct Answer ✔blood transfusion- will increase
iron stores
Chelation therapy-deferasirox & deferiprone
bone marrow transplant
Type 1 hypersensitivity -Correct Answer ✔Mediated by IgE antibody
Anaphylaxis, allergic rhinitis, asthma
NR 507
, NR 507
Type 2 hypersensitivity -Correct Answer ✔mediated by IgG antibodies and
macrophages
HITT reaction, transfusion reaction, Graves Disease
Graves disease -Correct Answer ✔IgG antibodies attach the TSH receptor causing an
over production of thyroid hormones leading the hyperthyroidism
tx: beta blockers for tachycardia, methimazole (not for pregnant), propylthiouracil (for
pregnant), radioactive iodine therapy (not for pregnant)
Type 3 hypersensitivity -Correct Answer ✔neutrophil mediated reaction
immune complexes activate complement system & neutrophils resulting in tissue
destruction
-Lupus, serum sickness
systemic lupus erythematosus -Correct Answer ✔B&T cells are over reactive causing
production of antibodies
DX with ANA antibody
TX with NSAIDS for pain
Which of the following client(s) should the nurse practitioner (NP) recognize as being at
risk for developing folate deficiency? Select all that apply.
A 30-year-old client with severe anorexia nervosa
A 19-year-old client with sickle cell disease
A 27-year-old client who is newly pregnant and breastfeeding their toddler
A 40-year-old client with celiac disease
A 32-year-old client who had a gastrectomy one year ago -Correct Answer ✔A 30-year-
old client with severe anorexia nervosa
A 27-year-old client who is newly pregnant and breastfeeding their toddler
A 40-year-old client with celiac disease
What medications impact the absorption of B12 -Correct Answer ✔Metformin, H2
receptor blockers, PPI
What medications impact the absorption of folate -Correct Answer ✔anticonvulsants
and methotrexate
A nurse practitioner (NP) evaluates a 45-year-old client who presents with fatigue and
weakness. The NP diagnoses the client with anemia of chronic disease. What is the
primary pathophysiological mechanism causing this normocytic anemia?
Excessive blood loss
Defective erythropoiesis
Impaired iron absorption
NR 507
NR 507 Midterm Exam Study Questions and
Answers Graded A+ 2025
Which client should the nurse practitioner (NP) recognize as most at risk of developing
iron deficiency anemia?
A 25-year-old client who recently became pregnant
A 40-year-old client with a history of peptic ulcers
A 30-year-old client who donates blood every 3 months
A 50-year-old client with congestive heart failure -Correct Answer ✔A 30-year-old client
who donates blood every 3 months
The nurse practitioner (NP) reviews a client's laboratory results. Which laboratory result
best reflects the client's level of iron stores?
Transferrin saturation
Hemoglobin
Serum iron
Serum ferritin
Hematocrit
Total iron-binding capacity -Correct Answer ✔Serum ferritin
The nurse practitioner (NP) is caring for a client with beta thalassemia major. The NP
should anticipate the client will require what? -Correct Answer ✔a bloos transfusion
The nurse practitioner (NP) is counseling a client with iron deficiency anemia about
dietary needs. Which instruction(s) should the NP include? Select all that apply.
Avoid drinking tea or coffee with meals
Consume lean red meat
Increase intake of calcium-rich foods
Consume iron-fortified cereal
Consume vitamin C-rich foods with iron-rich meals -Correct Answer ✔Avoid drinking tea
or coffee with meals
Consume lean red meat
Consume iron-fortified cereal
Consume vitamin C-rich foods with iron-rich meals
A nurse practitioner (NP) is providing pre-conception counseling to a couple, both of
whom are carriers of thalassemia. Which of the following actions should the NP take?
Select all that apply.
Encourage the couple not to conceive.
Refer the couple for genetic counseling.
NR 507
,NR 507
Explain what it means to be a carrier of thalassemia.
Discuss ways to prevent naturally conceiving a child with thalassemia.
Discuss inheritance patterns of thalassemia. -Correct Answer ✔Refer the couple for
genetic counseling.
Explain what it means to be a carrier of thalassemia.
Discuss inheritance patterns of thalassemia.
The nurse practitioner (NP) assesses the client on a follow-up visit after the initiation of
treatment for thalassemia including administration of blood transfusions. What three (3)
assessments should the NP prioritize to evaluate client outcomes? Select 3.
Dietary intake
Developmental milestones
Ferritin level
Hemoglobin level
Energy level -Correct Answer ✔Ferritin level
Hemoglobin level
Energy level
Which of the following clients should the nurse practitioner (NP) recognize as being
most at risk for developing vitamin B-12 deficiency anemia?
An infant who is exclusively breastfed
Middle adult client who eats a high-protein diet
A client who is pregnant
Adult client who had a vertical sleeve gastrectomy -Correct Answer ✔Adult client who
had a vertical sleeve gastrectomy
Mean Corpuscular Hemoglobin Concentration (MCHC) -Correct Answer ✔indicates
hemoglobin concentration in RBCs
Ferritin -Correct Answer ✔total iron stores; low levels indicate iron deficiency
microlytic anemia -Correct Answer ✔small RBC's
-iron deficiency
-thalassemia
Thalassemia beta major treatment -Correct Answer ✔blood transfusion- will increase
iron stores
Chelation therapy-deferasirox & deferiprone
bone marrow transplant
Type 1 hypersensitivity -Correct Answer ✔Mediated by IgE antibody
Anaphylaxis, allergic rhinitis, asthma
NR 507
, NR 507
Type 2 hypersensitivity -Correct Answer ✔mediated by IgG antibodies and
macrophages
HITT reaction, transfusion reaction, Graves Disease
Graves disease -Correct Answer ✔IgG antibodies attach the TSH receptor causing an
over production of thyroid hormones leading the hyperthyroidism
tx: beta blockers for tachycardia, methimazole (not for pregnant), propylthiouracil (for
pregnant), radioactive iodine therapy (not for pregnant)
Type 3 hypersensitivity -Correct Answer ✔neutrophil mediated reaction
immune complexes activate complement system & neutrophils resulting in tissue
destruction
-Lupus, serum sickness
systemic lupus erythematosus -Correct Answer ✔B&T cells are over reactive causing
production of antibodies
DX with ANA antibody
TX with NSAIDS for pain
Which of the following client(s) should the nurse practitioner (NP) recognize as being at
risk for developing folate deficiency? Select all that apply.
A 30-year-old client with severe anorexia nervosa
A 19-year-old client with sickle cell disease
A 27-year-old client who is newly pregnant and breastfeeding their toddler
A 40-year-old client with celiac disease
A 32-year-old client who had a gastrectomy one year ago -Correct Answer ✔A 30-year-
old client with severe anorexia nervosa
A 27-year-old client who is newly pregnant and breastfeeding their toddler
A 40-year-old client with celiac disease
What medications impact the absorption of B12 -Correct Answer ✔Metformin, H2
receptor blockers, PPI
What medications impact the absorption of folate -Correct Answer ✔anticonvulsants
and methotrexate
A nurse practitioner (NP) evaluates a 45-year-old client who presents with fatigue and
weakness. The NP diagnoses the client with anemia of chronic disease. What is the
primary pathophysiological mechanism causing this normocytic anemia?
Excessive blood loss
Defective erythropoiesis
Impaired iron absorption
NR 507
