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NRNP 6550 FINAL EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED

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NRNP 6550 FINAL EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED Terms in this set (188) Urine culture with UTI 100.000 colonies in asymptomatic: bacteruria 10 - 10.000 colonies in symptomatic patients but also pyuria pyuria: more than 10 leukocytes elevated erythrocytes with pyelonephritis WBC in urine false positive with tumor, urethritis and poor collection technique Repeat in pregnant women Lower urinary tract UTI and upper urinary tract UTI bladder and urethra: cystitis/ urethritis/ prostatitis kidney and ureters: pyelonephritis/ renal abcess Uncomplicated and complicated uti Uncomplicated: in normal working urinary tract Complicated: defects in urinary tract or with other health problems Common pathogens for UTI E.coli (elderly women) Staphylococcus proteus mirabilis (elderly men) Klebsiella enterecoccus pseudomonas Providencia (institutionalized) Fungus: candida Risk factors for UTI Female critically ill elderly catheter (caused by biofilm) DM calculi, tumor, stricture neurogenic bladder Women: sexual intercourse or new sex partner pregnancy previous UTI Men: prostate enlargement prostatitis lack of circumcision gay HIV Findings UTI Lower: Dysuria/ urgency/ frequency/ incontinence suprapubic pain hematuria fever/ chills uncommon No flank pain Upper: flank pain fever and chills hematuria n/v ams (in elderly) malaise tachycardia/ tachypnea Testing and results for UTI Gold standard: urine culture and sensitivity: detection of bacteria. Start with POC: urine analysis. UA: pos for nitrite or leukocyte or blood CBC: leukocyte with left shift in pyelonephritis For recurrent UTI in women or UTI in men rule out obstruction, calculi, or necrosis with: xr voiding CT abdomen US pelvis MRI pelvis Management acute cystitis First line: - Single dose Fosfomycin (monurol) - 3 day: sulfa: trimethoprim/ sulfa (bactrim) (do not give near delivery of baby, give cephalexin instead) or sulfa - 5 days: nitrofurantoin, caution in elderly Second line: - qiunolones: ciprofloxain or levofloxacin for 3 days (not for pregnant women!) - B-lactams: amoxi-clav, cefdinir for 3 - 7 days Management uncomplicated upper UTI Outpt: quinolone: ciprofloxacin for 7 days or levofloxacin for 5 days Sulfa: trimethoprim/ sulfa (bactrim) for 14 days Inpt: Ceftriaxone or cefotaxime Ampicillin CAUTI: bacterial: treat with AB for 7 days Candiduria: fluconazole for 14 days Discomfort: Pyridium Management acute complicated bacterial pyelonephritis - Admit - Aminoglycosides: gentamicin/ tobramycin (not for monotherapy), based on renal function (trough less than 2 and peak level 5-10mg/L) and do not give for CKD - Ampicillin - Cefazolin - Cefotaxime and Ceftriaxon based on obesity and pulm disease

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3/29/25, 8:02 NRNP 6550 Final |
AM
NRNP 6550 FINAL EXAM QUESTIONS AND ANSWERS WITH COMPLETE
SOLUTIONS VERIFIED
Terms in this set (188)


100.000 colonies in asymptomatic: bacteruria
10 - 10.000 colonies in symptomatic patients but also pyuria
pyuria: more than 10 leukocytes
elevated erythrocytes with pyelonephritis
Urine culture with UTI WBC in urine


false positive with tumor, urethritis and poor collection technique


Repeat in pregnant women

Lower urinary tract UTI and upper bladder and urethra: cystitis/ urethritis/ prostatitis
urinary tract UTI kidney and ureters: pyelonephritis/ renal abcess

Uncomplicated: in normal working urinary tract
Uncomplicated and complicated uti
Complicated: defects in urinary tract or with other health problems

E.coli (elderly women)
Staphylococcus
proteus mirabilis (elderly men)
Klebsiella
Common pathogens for UTI
enterecoccus
pseudomonas
Providencia (institutionalized)
Fungus: candida




1/22

,3/29/25, 8:02 NRNP 6550 Final |
AM
Female
critically ill
elderly
catheter (caused by
biofilm) DM
calculi, tumor, stricture
neurogenic bladder
Women:
Risk factors for UTI sexual intercourse or new sex partner
pregnancy
previous UTI
Men:
prostate enlargement
prostatitis
lack of circumcision
gay
HIV


Lower:
Dysuria/ urgency/ frequency/ incontinence
suprapubic pain
hematuria
fever/ chills uncommon
No flank pain


Findings UTI Upper:
flank pain
fever and
chills
hematuria
n/v
ams (in elderly)
malaise
tachycardia/ tachypnea
Gold standard: urine culture and sensitivity: detection of bacteria. Start with POC:
urine analysis.
UA: pos for nitrite or leukocyte or blood
CBC: leukocyte with left shift in pyelonephritis
For recurrent UTI in women or UTI in men rule out obstruction, calculi, or necrosis
Testing and results for UTI
with:
xr voiding
CT
abdomen
US pelvis
MRI pelvis
First line:
- Single dose Fosfomycin (monurol)
- 3 day: sulfa: trimethoprim/ sulfa (bactrim) (do not give near delivery of baby, give
cephalexin instead) or sulfa
Management acute cystitis - 5 days: nitrofurantoin, caution in elderly


Second line:
- qiunolones: ciprofloxain or levofloxacin for 3 days (not for pregnant women!)
- B-lactams: amoxi-clav, cefdinir for 3 - 7 days




2/22

, 3/29/25, 8:02 NRNP 6550 Final |
AM
Outpt:
quinolone: ciprofloxacin for 7 days or levofloxacin for 5 days
Sulfa: trimethoprim/ sulfa (bactrim) for 14 days


Inpt:
Ceftriaxone or cefotaxime
Management uncomplicated upper UTI Ampicillin


CAUTI:
bacterial: treat with AB for 7 days
Candiduria: fluconazole for 14 days


Discomfort: Pyridium


- Admit
- Aminoglycosides: gentamicin/ tobramycin (not for monotherapy), based on renal
Management acute complicated bacterial function (trough less than 2 and peak level 5-10mg/L) and do not give for
pyelonephritis CKD
- Ampicillin
- Cefazolin
- Cefotaxime and Ceftriaxon based on obesity and pulm disease
Serum glucose at least 180mg/dl for glucose to appear in urine


Glucose in ua caused by:
- Fancone Syndrome (bad wall: caused by ahminoglycosides for example)
- DM
- Cushing's
Urine analysis: glucose and ketones
- Vit C can give false negative


Ketones in urine:
- Alcohol
- Diabetic
- Starvation

-Acute renal function loss with inability to excrete metabolic waste products (urea
nitrogen and creatinine) to inability to maintain fluid and electrolyte balance.
Acute Kidney Injury
- Resolves within 3mo
- classified with RIFLE or etiology

Risk: creatinine up x 1.5 from baseline, GFR decrease more than 25% and UO less than
0.5ml/kg/hr for 6hr


Injury: creatinine up x 2 from baseline, GFR decrease more than 50% and UO less
than 0.5ml/kg/hr for 12hr

RIFLE
Failure: creatinine up x 1.5 from baseline, GFR decrease more than 25% and UO
less than 0.3ml/kg/hr for 12hr or anuria for 12hr


Loss: Complete loss of renal function for more than 4 weeks


End-stage Kidney Disease: RRT need for more than 3mo




3/22

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