ATI PHARMACOLOGY RN 2025
LATEST UPDATED EXAM verified
and passed by experts
Hexacholorphene (pHisoHex) [antiseptic solution] Caution - CNS stimulation if sufficient
amts are absorbed through skin or mucous membranes; avoid if pregnant/breastfeeding
Auranofin (Ridaura) [gold salt] indication - slows the progression of rheumatoid arthritis;
takes 4-6 months of therapy to achieve therapeutic effect; SE: renal toxicity (less toxic
through oral route than IM route), severe blood dyscrasias, GI rxns
Thiazides—SE - hyperuricemia (common SE); assess: uric acid levels
Simvastatin (Zocor)—SE - muscle weakness/aches; Assess: Creatine Kinase (released
w/severe muscle injury)
Amitriptyline (Elavil) [tricyclic antidepressant] SE - orthostatic hypotension, sedation, &
confusion
Narcotic (opiate) analgesic—SE - papillary constriction, ↓BP, ↓HR, ↓ GI mobility
Antihistamines indication - allergy-induced symptoms
Mucolytic indication - ↓ viscosity of mucus plugs making them easier to expel
Antitussive indication - used to suppress a cough
Decongestant indication - used to treat nasal congestion
Bulk-forming laxatives (Metamucil) Use - take w/large amounts of water to prevent a
gel-like mass to ↑ constipation
Gentamicin (Garamycin) [aminoglycoside antibiotic] SE - nephrotoxicity & ototoxicity
Digoxin [cardiac glycoside] that ↓ HR. intervention - assess apical HR for 1 min. Contact
DR if HR < 60bpm
Lorazepam (ativan) [benzodiazepine]: SE - abrupt cessation can →seizures RT physical
addiction
, Dantrolene sodium (Dantrium)—SE - hepatitis (highest risk for women 35yrs or taking lg
doses)
Synergistic effect - effect of combined drugs greater than either of drugs alone
Acetaminophen (Tylenol)—SE - Liver damage w/ high doses
Diuretic therapy—Assess - K+ values to prevent dysrhythmias; ↓ Na+, ↓ Cl-, & ↓ Mg 2+
What does Zidovudine (AZT) - only anti-retroviral drug that reduces maternal-fetal
transmission of HIV virus
Digoxin (lanoxin) SE - blurred/double vision
Guaifenesin SE - can cause drowsiness
Estrogen (premarin) SE - ↑ risk of Thromboembolism with s/s: SOB, severe headache,
vomiting, sudden acute pain in the calves, legs, chest, abdomen.
Doxepin (Sinequan) [anticholinergic] SE - urinary retension, constipation, drying of
nasal/oral secretons, ↑HR
Albuterol (Proventil) [sympathomimetic/ adrenergic beta-2 agonist] Contraindicated -
with MAOIs (can↑ action of albuterol and → HTN crisis); β-blockers can inhibit the
therapeutic effects Use: invert canister, shake before use, rinse mouth after use, w/new
inhaler perform test spray
Levothryoxine (T4) Indication - hypothyroidism RT dysfxn of hypothalamus, pituitary, or
thyroid gland
Cephalosporins (Keflex) - allergy to cephalosporins is considered a precaution for taking
penicillins
Phenobarbital [Barbiturates]; interventions for anticonvulsant therapy - assess for resp.
depression, excess sedation from toxic effects, IV at < 50mg/min, avoid extravasation
(alkaline→skin damage)
Sumatriptan (Imitrex) use - when migraine symptoms appear and again in 1 hr if
symptoms persist
Route—fastest/most effective - intravenous
Narcan [opioid antagonist] - therapeutic action: improvement of respiratory rate
Baclofen (Lioresal) Therapeutic action - ↓ frequency & severity of muscle spasms
Erythromycin (Erythrocin) [macrolide] SE - liver toxicity
LATEST UPDATED EXAM verified
and passed by experts
Hexacholorphene (pHisoHex) [antiseptic solution] Caution - CNS stimulation if sufficient
amts are absorbed through skin or mucous membranes; avoid if pregnant/breastfeeding
Auranofin (Ridaura) [gold salt] indication - slows the progression of rheumatoid arthritis;
takes 4-6 months of therapy to achieve therapeutic effect; SE: renal toxicity (less toxic
through oral route than IM route), severe blood dyscrasias, GI rxns
Thiazides—SE - hyperuricemia (common SE); assess: uric acid levels
Simvastatin (Zocor)—SE - muscle weakness/aches; Assess: Creatine Kinase (released
w/severe muscle injury)
Amitriptyline (Elavil) [tricyclic antidepressant] SE - orthostatic hypotension, sedation, &
confusion
Narcotic (opiate) analgesic—SE - papillary constriction, ↓BP, ↓HR, ↓ GI mobility
Antihistamines indication - allergy-induced symptoms
Mucolytic indication - ↓ viscosity of mucus plugs making them easier to expel
Antitussive indication - used to suppress a cough
Decongestant indication - used to treat nasal congestion
Bulk-forming laxatives (Metamucil) Use - take w/large amounts of water to prevent a
gel-like mass to ↑ constipation
Gentamicin (Garamycin) [aminoglycoside antibiotic] SE - nephrotoxicity & ototoxicity
Digoxin [cardiac glycoside] that ↓ HR. intervention - assess apical HR for 1 min. Contact
DR if HR < 60bpm
Lorazepam (ativan) [benzodiazepine]: SE - abrupt cessation can →seizures RT physical
addiction
, Dantrolene sodium (Dantrium)—SE - hepatitis (highest risk for women 35yrs or taking lg
doses)
Synergistic effect - effect of combined drugs greater than either of drugs alone
Acetaminophen (Tylenol)—SE - Liver damage w/ high doses
Diuretic therapy—Assess - K+ values to prevent dysrhythmias; ↓ Na+, ↓ Cl-, & ↓ Mg 2+
What does Zidovudine (AZT) - only anti-retroviral drug that reduces maternal-fetal
transmission of HIV virus
Digoxin (lanoxin) SE - blurred/double vision
Guaifenesin SE - can cause drowsiness
Estrogen (premarin) SE - ↑ risk of Thromboembolism with s/s: SOB, severe headache,
vomiting, sudden acute pain in the calves, legs, chest, abdomen.
Doxepin (Sinequan) [anticholinergic] SE - urinary retension, constipation, drying of
nasal/oral secretons, ↑HR
Albuterol (Proventil) [sympathomimetic/ adrenergic beta-2 agonist] Contraindicated -
with MAOIs (can↑ action of albuterol and → HTN crisis); β-blockers can inhibit the
therapeutic effects Use: invert canister, shake before use, rinse mouth after use, w/new
inhaler perform test spray
Levothryoxine (T4) Indication - hypothyroidism RT dysfxn of hypothalamus, pituitary, or
thyroid gland
Cephalosporins (Keflex) - allergy to cephalosporins is considered a precaution for taking
penicillins
Phenobarbital [Barbiturates]; interventions for anticonvulsant therapy - assess for resp.
depression, excess sedation from toxic effects, IV at < 50mg/min, avoid extravasation
(alkaline→skin damage)
Sumatriptan (Imitrex) use - when migraine symptoms appear and again in 1 hr if
symptoms persist
Route—fastest/most effective - intravenous
Narcan [opioid antagonist] - therapeutic action: improvement of respiratory rate
Baclofen (Lioresal) Therapeutic action - ↓ frequency & severity of muscle spasms
Erythromycin (Erythrocin) [macrolide] SE - liver toxicity
