MSN 571 PHARMACOLOGY MIDTERM EXAM 2 LATEST VERSIONS (MAY 2025 VERSION A
& B) ALL QUESTIONS AND CORRECT ANSWERS|ALREADY GRADED A+
lithium -(answer)check NA levels 2x per week until therapeutic levels and then monthly
ED50 -(answer)defined therapeutic response in 50% of the population
pharmacogenetics -(answer)the study of genetic factors that influence an individuals response to a
specific drug
pharmacogenomics -(answer)the study of how genetics play a role in a persons response to drugs
(MAT) Medication assisted therapy -(answer)gold standard for treatment of opioid use disorder
MAT drugs -(answer)methadone, buprenorphine with or without naloxone, naltrexone
Methadone -(answer)full mu-opioid agonist. The binding at adequate doses can result in the reduction
of heroin or other opioid use by decreased craving and withdrawal from other opioids
methadone -(answer)schedule II, 5 days to reach steady state, no ceiling effect. higher risk of overdose
compared to buprenorphine
patients who may need lower dose of methadone -(answer)older than 60, use benzos, hx of cardiac
arrhythmias, brady, QT prolongation, electrolyte abnormalitiies, asthma, copd
methadone side effects -(answer)dizziness, sedation, light headedness, N/V, contipation, diaphoresis,
hypotension, cns depression, respiratory depression,
& B) ALL QUESTIONS AND CORRECT ANSWERS|ALREADY GRADED A+
lithium -(answer)check NA levels 2x per week until therapeutic levels and then monthly
ED50 -(answer)defined therapeutic response in 50% of the population
pharmacogenetics -(answer)the study of genetic factors that influence an individuals response to a
specific drug
pharmacogenomics -(answer)the study of how genetics play a role in a persons response to drugs
(MAT) Medication assisted therapy -(answer)gold standard for treatment of opioid use disorder
MAT drugs -(answer)methadone, buprenorphine with or without naloxone, naltrexone
Methadone -(answer)full mu-opioid agonist. The binding at adequate doses can result in the reduction
of heroin or other opioid use by decreased craving and withdrawal from other opioids
methadone -(answer)schedule II, 5 days to reach steady state, no ceiling effect. higher risk of overdose
compared to buprenorphine
patients who may need lower dose of methadone -(answer)older than 60, use benzos, hx of cardiac
arrhythmias, brady, QT prolongation, electrolyte abnormalitiies, asthma, copd
methadone side effects -(answer)dizziness, sedation, light headedness, N/V, contipation, diaphoresis,
hypotension, cns depression, respiratory depression,
