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1. Which of the following statements about pharmacodynamic phase is cor-
rect?: Pharmacodynamic phase studies the amount of drug that is excreted into
breast milk.
Pharmacodynamic phase is related to the drug-receptor interaction and its biological
effect. ***
Optimization of the pharmacodynamic phase improves drug bioavailability.
Pharmacodynamic phase is concerned with the amount of drug that is metabolized
by the liver.
Pharmacodynamic phase is concerned with drug absorption.
2. Which phase is most concerned with drug absorption and metabolism?: -
Pharmacokinetic phase ***
Storage phase
Pharmacodynamic phase
Distribution phase
Pharmaceutical phase
3. Bioavailability is affected by which of the following factors?: Patient's weight
Patient's age
Patient's gender
Drug's dose
Drug's solubility ***
4. What is true about competitive inhibitors?: They promote the binding of an
agonist at an active site.
Competitive and allosteric inhibitors act at the same place of the molecule.
They are less effective than agonists.
, Advanced Pharmacology NURS 6521
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They bind to a different place on the same molecule.
They act at the same site as the drug. ***
5. Which category of substances is most likely to increase an activator's (i.e.
an agonist's ) efficacy?: None
Competitive inhibitor
Negative allosteric modulator
Allosteric inhibitor
Allosteric agonist ***
6. Which of the following drug characteristics makes a drug more likely to
enter a cell through a protein channel?: Basophilic property
Water solubility ***
Neutrality
Acidophilic property
Fat solubility
7. What type of substances can act as agonists or antagonists? Select all that
apply.: Hormones **
Target cells
Receptors
Drugs **
Neurotransmitters **
8. What effect does an antagonist drug have over the receptors?: Causes the
associated cellular process to be activated
Increases the heart rate
Stimulates bronchodilation in the lungs