NURS 660 Exam 3||Questions and Answers||2025||
1. What is the medication that is the antidote for alprazolam?
Flumazenil
2. What is the MOA of pregabalin that makes it alleviate pain for people with fibromyalgia or
chronic fatigue?
Binds to the alpha 2 delta sub-units of voltage-sensitive calcium channels
3. What is the antagonist of caffeine?
Adenosine
4. Diagnose this patient: Patient comes in with a CC of anxiety. She has been excessively
worrying, experiencing increased arousal, increased tiredness and irritability. What is the primary
and least likely diagnosis?
GAD; Panic Disorder
5. Somebody with anxiety worries about having a panic attack, in addition to having mood
changes, and avoids things in order not to have a panic attack.
Panic disorder
6. A woman was raped, and continues to have fear of opposite sex on her way to parking garage.
Which two areas of the brain are involved?
Amygdala and hippocampus
7. MOA of modafinil (Provigil). How does it promote normal wakefulness?
Histamine, NE at alpha adrenergic receptor sites, dopamine at D2 receptors
8. What is the MOA of eszopiclone? What receptors does it act on?
Binds to GABA receptors to increase GABA to increase sleepiness
9. Which would be the first line appropriate pharmacological agent for PTSD?
Paroxetine
10. What mediation is used to alleviate to help cognitive pain and physical symptoms in
fibromyalgia?
Milnacepran (Savella)
, 11. With the difficulty breathing is related hypothetically to the activation of what area of the
brain?
Parabrachial nucleus
12. What medications are good for falling asleep, "sleep induction", and are not addictive?
Suvorexant (Belsmora)
13. Know the MOA of buspirone. Which receptor does it primarily act upon?
Serotonin 1a 5HT1A partial agonist
14. How does melatonin improve sleep? What receptors does it act on? Agonist or antatonist?
Secreted by the pineal gland to attach to receptors in the suprachiasmatic nucleus to regulate the
circadian rhythm; agonist
15. Current diagnosis of generalized anxiety disorder (GAD), difficulty concentrating, as well as
problems falling asleep. She gets very angry over basic things and is very moody in general, has
excessive stressful reactions, concentrates, and irritability. What is going on in her brain?
a. Dysfunction of the amygdala and CTSC (serotonin/noradrenaline)
16. Pt is coming in for detox with a long history of alcohol abuse, HTN, and cirrhosis. He reports
12 beers daily for weeks. Has w/d seizures when he tries to stop drinking on his own. So he has
elevated AST, LFT....what agent would you choose to detox him?
Lorazepam
17. Someone comes in with chronic hepatitis and also has chronic neuropathic pain. What
medication would you AVOID prescribing to this patient and why?
Cymbalta elevates LFTs
18. Benzodiazepine patient education
Avoiding ETOH may cause dizziness, may slow the heart rate, and avoid sedating antihistamines
19. What medication or drug class is second-line treatment for fibromyalgia?
Cyclobenzaprine
20. What drug is a melatonin receptor agonist?
Ramelteon, tasimeltion
21. What is the MOA of trazodone?
5HT2C antagonist, H1 antagonist
1. What is the medication that is the antidote for alprazolam?
Flumazenil
2. What is the MOA of pregabalin that makes it alleviate pain for people with fibromyalgia or
chronic fatigue?
Binds to the alpha 2 delta sub-units of voltage-sensitive calcium channels
3. What is the antagonist of caffeine?
Adenosine
4. Diagnose this patient: Patient comes in with a CC of anxiety. She has been excessively
worrying, experiencing increased arousal, increased tiredness and irritability. What is the primary
and least likely diagnosis?
GAD; Panic Disorder
5. Somebody with anxiety worries about having a panic attack, in addition to having mood
changes, and avoids things in order not to have a panic attack.
Panic disorder
6. A woman was raped, and continues to have fear of opposite sex on her way to parking garage.
Which two areas of the brain are involved?
Amygdala and hippocampus
7. MOA of modafinil (Provigil). How does it promote normal wakefulness?
Histamine, NE at alpha adrenergic receptor sites, dopamine at D2 receptors
8. What is the MOA of eszopiclone? What receptors does it act on?
Binds to GABA receptors to increase GABA to increase sleepiness
9. Which would be the first line appropriate pharmacological agent for PTSD?
Paroxetine
10. What mediation is used to alleviate to help cognitive pain and physical symptoms in
fibromyalgia?
Milnacepran (Savella)
, 11. With the difficulty breathing is related hypothetically to the activation of what area of the
brain?
Parabrachial nucleus
12. What medications are good for falling asleep, "sleep induction", and are not addictive?
Suvorexant (Belsmora)
13. Know the MOA of buspirone. Which receptor does it primarily act upon?
Serotonin 1a 5HT1A partial agonist
14. How does melatonin improve sleep? What receptors does it act on? Agonist or antatonist?
Secreted by the pineal gland to attach to receptors in the suprachiasmatic nucleus to regulate the
circadian rhythm; agonist
15. Current diagnosis of generalized anxiety disorder (GAD), difficulty concentrating, as well as
problems falling asleep. She gets very angry over basic things and is very moody in general, has
excessive stressful reactions, concentrates, and irritability. What is going on in her brain?
a. Dysfunction of the amygdala and CTSC (serotonin/noradrenaline)
16. Pt is coming in for detox with a long history of alcohol abuse, HTN, and cirrhosis. He reports
12 beers daily for weeks. Has w/d seizures when he tries to stop drinking on his own. So he has
elevated AST, LFT....what agent would you choose to detox him?
Lorazepam
17. Someone comes in with chronic hepatitis and also has chronic neuropathic pain. What
medication would you AVOID prescribing to this patient and why?
Cymbalta elevates LFTs
18. Benzodiazepine patient education
Avoiding ETOH may cause dizziness, may slow the heart rate, and avoid sedating antihistamines
19. What medication or drug class is second-line treatment for fibromyalgia?
Cyclobenzaprine
20. What drug is a melatonin receptor agonist?
Ramelteon, tasimeltion
21. What is the MOA of trazodone?
5HT2C antagonist, H1 antagonist
