PHARMACOLOGY
QUESTION no:1
Noradrenaline can stimulate a receptor and contract blood vessels,so blood pressure
(BP) of the patient increases.But the decreased heart rate (HR) caused by increase of BP
appears.
1:- Which one is drug action ? Which one is drug effect ?
2:- Which one is direct effect , which one is indirect effect ?
3:- Why does HR decrease ?
Answer 1:- In the given case the drug action is the stimulation of alpha receptors,
which results in the the drug effects that are increased blood pressure and decreased
heart rate.
Answer 2:- The direct effect is the increased blood pressure which results in the
indirect effect of decreased heavy rate.
Answer 3:- The decrease in heart rate is caused by the increase in blood pressure. Heart
rate is decreased with noradrenaline release but it is a delayed effect. Noradrenaline
interacts with alpha receptors in the arteries, thereby causing constriction of blood
vessel. Blood vessel constriction triggers a reflex pathway that causes the heart rate to
slow down.
QUESTION NO 2:
A 55 years old man visited the doctor due to abdominal colic, vomiting and diarrhea.
He is diagnosed as acute gastroenteritis
Treatment:- Tab.lomefloxcin, 0.3g, bid, po Inj. Atropine,1mg,im,st.After
administration, the abdominal pain was relieved, but some symptoms like dry skin,
flushed face, dry mouth ,blurred vision, and difficulty of urination