Drug Design and QSAR Parameters

LEARNING MATERIAL
COURSE: B.PHARMACY, 6th Sem, Medicinal Chemistry, BP -601T


Module 05 Introduction to Drug Design.
Combinatorial chemistry




Ms. Baljeet Kaur
Assistant Professor
Department of Pharmaceutical Chemistry
ASBASJSM College of Pharmacy, Bela (Ropar)

,Objectives:
1. Understand the importance of Drug Design and
different technique for drug designing.
2.Know the importance of SAR ofdrugs.

Learning Outcomes:
1.Student will learn about the different techniques of
drug designing.
2. Student will learn about the Relation of drug and its
Activity.

,Quantitative Structure Activity
Relationships (QSAR)

, CONTENTS


 INTRODUCTION
 HYDROPHOBICITY OF MOLECULE
 HYDROPHOBICITY OF SUBSTITUENTS
 ELECTRONIC EFFECT
 STERIC EFFECT
 HANSCH EQUATION
 C R AIG PLOT
 REFERENCES