MN553 UNIT 7 TEST|| ACTUAL EXAM ALL QUEST
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WhatgisgthegdruggofgchoicegforgstagegAgheartgfailureg-gANSWER:gACEs
WhatgmedicationgisgconsideredgingStagegAgheartgfailuregbutgisgmoregexpensivegthangAC
Esg-gANSWER:gARBs
WhatgdrugsgwillgyougseegingmostgstagegBgheartgfailuregpatientsg-
gANSWER:gBetagblockers
Whatgmedicationsgwillgyougseegingallgstagegbgheartgfailuregpatientsg-gANSWER:
ACEs
WhatgdrugsgwillgyougseegingStagegBgheartgfailuregpatientsgwhogcannotgtolerategACEs
-gANSWER:gARBs
Whatgmedicationsgwillgyougseegingallgstagegcgheartgfailuregpatientsg(5)g-gANSWER:
ACESs
BBs
Diuretics
Digoxin
,2g|gPg ag gg e
Spironolactone
WhatgmedicationsgwillgyougseegingstagegDgheartgfailureg(5)g-gANSWER:gSacubitril
Valsartang(Entresto)
ACEs
ARBs
Inotropes:gdobutamine
Ventriculargassistinggdevices
Transplantation
Hospice
PharmacodynamicsgofgACEsg-gANSWER:gInhibitgangiotensin-
convertinggenzymeg(ACE)gwhichgresultsgingdecreasedgproductiongofgbothgangiotens
ingIIgandgaldosterone
WhatgaregthegspecialgcharacteristicsgofgACEsg-
gANSWER:gCanglowergvasculargresistancegwithoutgdecreasinggcardiacgoutputg
(CO)gorgglomerulargfiltrationgrateg(GFR)
,3g|gPg ag gg e
Doesgnotgproducegreflexgtachycardia
UsesgforgACEsg-
gANSWER:gStronggevidencegforgCVgandgcerebrovasculargriskgreduction,gheartgfailure,g
andgslowinggrenalgdisease
OutcomesgofgACEsgongthegheartg-
gANSWER:gImprovesgoxygenationgtogheartgmuscle,gdecreasesginappropriategremo
delinggofgheartgmusclegaftergMIgorgwithgHF,greducesgeffectsgofgdiabetesgongthegkidn
eys
OutcomesgofgACEsgonginsuling-
gANSWER:gImprovesginsulingsensitivity,gdoesgnotgaffectgglucosegmetabolismgorgraisegs
erumglipidglevels
OutcomesgofgACEsgingpatientsgwithganginag-
gANSWER:gPreventsgformationgofgATgIIgandgdecreasesgpulmonarygvasculargresista
ncegbygdecreasinggretentiongofgsodiumgandgwatergandgreducinggextracellulargfluidga
ndgpreload
OutcomesgofgACEsgingpatientsgwithgdiabetesg-
gANSWER:gPreventsgslowgnephropathy
OutcomesgofgACEsgingpatientsgaftergangMIgandgHFg-
gANSWER:gPromotesgventriculargremodeling
Truegorgfalse
ACEsgaregequallygeffectivegingallgracesg-gANSWER:gFalse
NotgasgeffectivegingAfricangAmericans
, 4g|gPg ag gg e
HowgdogyougincreasegthegeffectsgofgACEsgingthegAfricangAmericangpopulationg-
gANSWER:gCombinegwithgagdiuretic
WhatgisgthegbiggestgriskgwithgACEsgingAAgandgAsiangpopulationsg-gANSWER:g3-
4gtimesggreatergriskgofgangioedema
ACEgADRsg-gANSWER:gDrygcoughg(bradykiningmediated)
Hypotension
Lossgofgtaste
Angioedema
Bloodgdycrasias
Teratogenicity
Hyperkalemia
Acutegrenalgfailure
Cholestaticgjaundice
Pancreatitis