2024gACTUALgEXAMg220gQUESTIONSgANDgCORRECTgDETAIL
EDgANSWERSg(VERIFIEDgANSWERS)g|ALREADYgGRADEDgA+
Thegnursegisgreviewinggtheglaboratorygtestgresultsgofgagchildgdiagnosedgwithgdisseminatedgintravascular
gcoagulationg(DIC).gWhichgofgthegfollowinggwouldgthegnurseginterpretgasgindicativegofgthisgdisorder?
A) Shortenedgprothrombingtime
B) Increasedgfibrinogenglevel
C) Positivegfibringsplitgproducts
D) Increasedgplateletsg-ganswer-C)gPositivegfibringsplitgproducts
Thegnursegisgcaringgforgagpostpartumgpatientgadmittedgtogthegintensivegcaregunitgwithgagdiagnosisgofgdis
seminatedgintravasculargcoagulationg(DIC).gWhatgisgthegdruggofgchoicegtogtreatgthisgproblem?
A. Heparin
B. Urokinase
C. Aspirin
D. Warfaring-ganswer-A.)gHeparin
IngthegICU,gagpostsurgicalgclientghasgdevelopedgsepsisgandgisgbeinggtreatedgwithgmultiplegmedications.gD
uringgthegmid-
morninggassessment,gwhichgfindinggleadsgthegnursegtogsuspectgthegclientgmaygbegdevelopinggagcomplic
ationgcalledgdisseminatedgintravasculargcoagulationg(DIC)?gSelectgallgthatgapply.
A) Headachesgassociatedgwithglightgsensitivity
B) Oozinggfromgallgpreviousgpuncturegandgintravenousgsites
C) DecreasedgO2gsaturationgandgdiminishedgbreathgsoundsginglowerglobes
D) Hemorrhagegfromgthegsurgicalgsitegrequiringgdeepgpressuregdressings
E) UrinegfromgthegFoleygcathetergisgbloodyg-ganswer-
D)gHemorrhagegfromgthegsurgicalgsitegrequiringgdeepgpressuregdressings
Aghealthy,gprimiparousg(first-
time)gmothergdeliveredgaghealthyginfantgseveralghoursgago,gbutgthegmotherghasgexperiencedgpostpartu
mghemorrhage.gWhichgofgthegfollowinggdisordersgisgmostglikelygtogunderliegthegclient'sgexcessivegbleedi
nggaftergdelivery?
A) Disseminatedgintravasculargcoagulation
,B) HemophiliagA
C) VongWillebrandgdisease
D) Thromboticgthrombocytopenicgpurpurag(TTP)g-ganswer-A)gDisseminatedgintravasculargcoagulation
WhatgisgthegconceptgbehindgheparingforgPTgwithgDIC?g-ganswer--
Itgpreventsgthegclottinggphasegfromgbeinggcompletedgwhichginhibitsgthegbreakdowngofgfibrinogen.
-
gItgalsoghelpsgavoidghemorrhagegbygpreventinggthegbodygfromgdepletinggentiregstagegofgcoagulationgfact
ors.
WhatgaregsomegacutegclinicalgmanifestationsgofgDIC?g-ganswer--
Directlygrelatedgtogbleedinggproblemsgsuchgas:
Petechia,gPurpura,goozinggfromgpuncturegsitesgorgsevereghemorrhaging.
HowgdoesgDICghappengingpostpartumghemorrhaging?g-ganswer--
Tissuegfactorsgreleasedgfromgnecroticgplace/fetalgtissuegorgamnioticgfluidgmygentergthegcirculation,ginciti
nggDIC.
WhatgisgagcommongcausegofgDIC?g-ganswer--Sepsis
AgpatientgwithgDICgisgatgaghighergriskgforgwhat?g-ganswer--Deficientgfluidgvolume
Increasedglevelsgofg ,g ,g ,gandg
willgbegnotedgingDIC:g-ganswer--
Fibrinolycin,gfibrinopeptidegA,gpositivegfibringsplitgproductsgandgD-dimers.
DICgcangoccurgsecondarygtogwhatgtypegofgconditions?gSelectgallgthatgapply:g-ganswer--Abrupitoplacente
-Amnioticgfluidgembolism
-Endotoxingsepsis
-Retainedgdeadgfetus
-Postghemorrhagegshock
-Hydatidformmole
-GynecologicgMalinganries
,DICgcangbegdecreasedgasgaglossgofgbalancegbetweengwhatgtwogactivities?g-ganswer--
Clotgforminggactivitygofgthrombin
-Clotglysingactivitygofgplasmin
WhatgaregsomegwaysgtogcombatgDIC?gSelectgallgthatgapply:g-ganswer--Anticoagulationgtherapyg(low-
gmoleculargweightgheparin)
-PackedgRBCs
-Plateletgconcentrate
-Antithrombing concentrate
-NonclottinggProtein-gcontaininggvolumegwillgexpandglike:gplasmagproteingfractiongorgalbumin
HowgdoesgHeparingworkgingthegcirculatorygsystem?g-ganswer--
Inhibitsgthrombusgandgclotgproductiongbygblockinggthegconversiongofgprothrombingtogthrombing&gfibro
gengtogfibrin.
WhatgaregsomegadversegeffectsgofgHeparin?gSelectgallgthatgapply:g-ganswer--Lossgofghair
-Bruising
-Chills
-Fever
-Osteoporosis
-Suppressiongofgrenalgfunction
IfgagPTghasgangallergicgreactiongtogHeparin,gwhatgdruggwouldgbegadministeredgasgtreatment?g-ganswer--
gLepiruding(refludan)
IngDIC,gmicroemboligmaygobstructgbloodgvesselsgandgcausegtissueghypoxia/gnecroticgdamagegtogwhichgo
rgangstructures?gSelectgallgthatgapply:g-ganswer--Kidneys
-Heart
-Lungs
-Brain
, ThegtreatmentgofgDICgisgdirectedgtowardgmanaginggwhat?g-ganswer--ThegPrimarygdisease
-Replacinggclottinggcomponents
-Preventinggfurthergactivationgofgclottinggmechanisms
HowgdogyougcorrectgthegclottinggfactorgdeficiencygingDIC?g-ganswer--TransitiongofgFFP
- "g"gplatelets
- "g"gfibrinogengcontaininggcryoprecipitate
HowgdoesgDICginitiategactivationgofgthegextrinsicgpathway?g-ganswer--
Occursgwithgliberationgofgtissuegfactorgandgassociatedgwithgobstetricgcomplications,gtrauma,gbacterialgs
epsisg&gcancer
HowgdoesgDICginitiategactivationgofgthegintrinsicgpathway?g-ganswer--
ActivatedgthroughgextensivegendothelialgdamagegwithgactivationgofgfactorgXII.gThisgresultsgfromgviruses,
ginfections,gimmunegmechanisms,gstasisgofgbloodgorgtemperaturegextremes.
WhatgaregsomegpotentialgtherapiesgtogDICgothergthangHeparin?g-ganswer--
Tissuegfactorgpathwayginhibitors,gantithrombin,gProteingCgconcentrates,g&ganti-
inflammatorygcytokinesglikegINL-I
WhatgaregsomegobstetricgconditionsgthatghavegbeengassociatedgwithgDIC?g-ganswer--
Abrupitogplacentratae
-Deadgfetusgsyndrome
-Pre-eclampsiag&geclampsia
-Amnioticgfluidgembolism
WhatgaregsomegCancersgthatghavegbeengassociatedgwithgDICg?g-ganswer--Metastaticgcancer
-Acutegleukemia
WhatgaregsomeginfectionsgassociationsgwithgDIC?g-ganswer--
Acutegbacterialginfectionsg(meningococalgmeningitis)
-Histoplasmosis,gAspergicrosis