NU641 NU 641 MIDTERM EXAM (NEW UPDATE) ADVANCED CLINICAL PHARMACOLOGY QS & AS GRADE A 100% CORRECT (VERIFIED ANSWERS)

1
NU




UNU641/ NU 641 MIDTERM EXAM: (NEW 2024/ 2 U U UU U U U U




025 UPDATE) ADVANCED CLINICAL PHARMACOLOGY
U U U U




| QS & AS| GRADE A| 100% CORRECT (VERIFIED ANS
U U U U U U U U U




WERS)




first line drug for strep throat - ANS ✓penicillin v potassium PO x10 days
u u u u u u u u u u u u u




if allergic to PCN, give amoxicillin
u u u u u




before prescribing antiHTN meds to newly diagnosed pt -
u u u u u u u u




u ANS ✓EKG & blood work
u u u u




thiazide diuretics - ANS ✓-cause ED
u u u u u




-first line of tx for uncomplicated stage I HTN
u u u u u u u u




PCN allergy - ANS ✓use macrolides instead
u u u u u u




amoxicillin - ANS ✓avoid in mono patients
u u u u u u




complication of quinolones - ANS ✓-Achilles tendon rupture
u u u u u u u




NU641/ NU u

, 2
NU
-do not use in children under 18 because of growing cartilage
u u u u u u u u u u




Benadryl - ANS ✓avoid in elderly u u u u u




use Claritin instead
u u




spironolactone - ANS ✓-potassium sparing diuretic u u u u u




-caution w/ ACE: watch for hyperkalemia
u u u u u




warfarin/coumadin - ANS ✓-do not take garlic, St. john's wart u u u u u u u u u




-increases bleeding time u u




sat john's wart - ANS ✓-used for depression, menopausal symptoms
u u u u u u u u u




-decreases effectiveness of digoxin & birth control (causes breakthrough bleeding)
u u u u u u u u u




-do not use with celexa
u u u u




antiplatelet meds - ANS ✓- u u u u




garlic can exaggerate effects & inhibit action of platelets in the body
u u u u u u u u u u u




-ex: indomethacin, dipyridamole, Plavix, aspirin
u u u u




blood thinners - ANS ✓-aspirin & warfarin
u u u u u u




-avoid garlic: can increase risk of bleeding
u u u u u u




NU641/ NU u

, 3
NU
protease inhibitors - ANS ✓-garlic may reduce blood levels of protease inhibitors
u u u u u u u u u u u




-used to treat HIV u u u




-ex: indinavir, ritinavir, saquinavir
u u u




SSRI - ANS ✓-zoloft u u u




-do not take st. john's wart, ginseng, ginko biloba
u u u u u u u u




-

risk of serotonin syndrome when using citalopram (celexa) with tramadol (ultram
u u u u u u u u u u




) or elavil
u u




-if 10 weeks of therapy is ineffective, change drug within the SAME class.
u u u u u u u u u u u u




side effects of diuretics - ANS ✓-hyperuricemia
u u u u u u




-hyperglycemia

-hypokalemia

-ED



disulfuram reaction - ANS ✓-changes the way your body breaks down alcohol
u u u u u u u u u u u




-alcohol with disulfiram causes nausea/vomiting, headache
u u u u u




-avoid alcohol 1 day before, during therapy, and 72 hours after
u u u u u u u u u u




NU641/ NU u