SBB Human Blood Groups 159 QUESTIONS WITH COMPLETE SOLUTION 2025

SBB Human Blood Groups| 159 QUESTIONS| WITH COMPLETE
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SOLUTIONS
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1. How would Ulex europaeus react with O, A, A2, B, A2B, A1B R
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BCs? - ✅✅✅O>A2>B>A2B>A1>A1B
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2. How could you distinguish serologically A1, A2 and A3 -
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u✅✅✅Dolichos biflorus can will react with A1 and not A2. u u u u u u u u u u




A3 yields mixed field reactions with anti-A and anti-A,B
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3. What is the correct order of type of RBCs to transfuse in an AB
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patient when AB RBCs are not available? Why? -
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u✅✅✅A, B, O; the residual anti- u u u u u




B in A RBCs is less immunogenic than the residual anti-
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A in B RBCs
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4. What type of RBCs would you transfuse to a patient with anti-
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G - ✅✅✅RBCs transfused must lack the D and C antigens
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5. Can you detect a weak D using Gel Technology? -
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u✅✅✅No, because there is no washing phase u u u u u u




[Date] 1

,6. Can an Rh positive father and Rh positive mother yield an Rh n
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egative child - u u




u✅✅✅Yes, if both parents are heterozygous for the D gen u u u u u u u u u




e. Inheritance is autosomal recessive
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7. What type of RBCs in regards to Rh phenotype would you tran
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sfuse in a patient with anti-f -
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u✅✅✅RBCs should be negative for the c and e antigens u u u u u u u u u




8. How could you solve an ABO discrepancy where Anti-
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M was causing aberrant results in reverse grouping when the
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forward type is consistent with A blood group and reverse as
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O? - u




u✅✅✅Treat A1 cells with ficin to denature the M antigen, u u u u u u u u u u




repeat reverse grouping with ficin-treated A1 cells.
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9. Why do you see an anti-N like specificity in dialysis patients? -
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u✅✅✅Formaldehyde induced antibody to 'N' due to for u u u u u u u




maldehyde used in dialysis procedures. u u u u




10. A patient types as follows: anti-A=4+, Anti-
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B=1+, A1 Cells=2+, B cells=4+. The ABO discrepancy led to sus
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picion of a possible cold autoantibody based on patient histo
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pry and diagnosis. RESt was used in an attept to adsorb the au
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[Date] 2

, toantobidy. The type was repeated with adsorbed plasma Ani
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t-A=4+, Anti- u




B=0, A1 cells=0, B cells=0. What could be the cause of this disc
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repancy? - ✅✅✅Anti-B was adsorbed out with RESt.
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11. What enzyme may be useful in distinguishing anti-
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Ge2? - ✅✅✅papainu u




12. The beta 1-3 linkage between galactose and N-
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acetylglucosamine is found in? - ✅✅✅secretions u u u u u




13. Represents Type II chain - ✅✅✅Beta 1- u u u u u u




4 linkage between galactose and N acetyl glucosamine
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14. Represents decreasing concentrations of H antigen on R
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BCs - ✅✅✅O>A2>B>A2B>A1>A1B
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15. The ABO genes are located on what chromosome -
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✅✅✅Chromosome 9
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16. Which glycosyltransferase is needed before A and B anti
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gens are formed? - ✅✅✅L-fucosyltransferase
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[Date] 3