SBB COMPLETE REVIEW EXAM | QUE
P P P P P
STIONS & ANSWERS (VERIFIED) |LAT
P P P P P
EST UPDATE | GRADED A+
P P P P
BandP3
CorrectPAnswer: macrocomplexPofPproteinsPincluding:
-Rh
-RhAG
-LW P(ICAM-4)
-GPA
-GPB
-CD47
WhatPcausesPMFPagglutination?
CorrectPAnswer: Transfusion
BMT
Chimera
A3
Tn
1
,Ankryin
CorrectPAnswer: mediatesPinteractionPbetweenPBandP3PandPunderlyingPrbcPskeleton
attachesPtoPspectrinPthroughPinteractionPwithPproteinP4.2
BandP4.1
CorrectPAnswer: mediatesPinteractionsPbetweenPGPCPandPunderlyingPrbcPskeleton
(gerbich)
Adducin
CorrectPAnswer: interactsPwithPdimericPBandP3P(associatedPwithPGPC)
ImportantPforPmaintainingPmembranePstability
Spectrin
CorrectPAnswer: majorPcomponentPofPunderlyingPskeleton
consistsPofP2Psubunits:PalphaP&Pbeta
ATPPsourcePforPRBCs
CorrectPAnswer: 90%PfromPGlycolysisP(Embden-MeyerhoffPpathway)
10%PfromPpentosePphosphatePpathway
MethemoglobinPReductasePPathway
CorrectPAnswer: necessaryPtoPmaintainPhemePironPinPferrousP(Fe2+)Pstate
2
,DeficiencyPcausesPaccumulationPofPmethemoglobin,PnonfunctionalPfromPofPHgb
LeuberingPRapaportPShunt
CorrectPAnswer: permitsPaccumulationPofP2,3-DPG
AllowsPrbcPtoPregulatePO2PtransportPduringPhypoxia
Embden-MeyerhoffPPathway
CorrectPAnswer: WholePanaerobicPglycolysisPpathwayPtakenPbyPrbc
generatesP90%PofPATPPneededPforPrbc
"TensePform"PofPHgb
CorrectPAnswer: DEOXYGENATED
wideningPofPbeta-chain
lowerPaffinityPforPO2
expelsP2,3-DPG
"RelaxedPform"PofPHgb
CorrectPAnswer: OXYGENATED
beta-chainPpulledPtogether
higherPaffinityPforPO2
expelsP2,3-DPG
"ShiftPRight"
3
, CorrectPAnswer: higherPP50Pvalue
decreasedPpHP(increasedPH+Pion),Pacidosis
increasedP2,3-DPG
higherPtemperature
highPpCO2
SeenPinPcompensatedPanemia/Pexercise
"ShiftPLeft"
CorrectPAnswer: lowerPP50Pvalue
increasedPpHP(decreasedPH+Pion),Palkalosis
decreasedP2,3-DPG
decreasedPATP
lowerPtemperatures
lowPpCO2
increasePK+
SeenPinPstoragePofPRBC
CompensatedPAnemiaPphysiologicPreactions
CorrectPAnswer: Increased:
-CardiacPoutputP(heartPrate,PstrokePvolume)
- BloodPflowP(vasodilation,Pshunting)
4
P P P P P
STIONS & ANSWERS (VERIFIED) |LAT
P P P P P
EST UPDATE | GRADED A+
P P P P
BandP3
CorrectPAnswer: macrocomplexPofPproteinsPincluding:
-Rh
-RhAG
-LW P(ICAM-4)
-GPA
-GPB
-CD47
WhatPcausesPMFPagglutination?
CorrectPAnswer: Transfusion
BMT
Chimera
A3
Tn
1
,Ankryin
CorrectPAnswer: mediatesPinteractionPbetweenPBandP3PandPunderlyingPrbcPskeleton
attachesPtoPspectrinPthroughPinteractionPwithPproteinP4.2
BandP4.1
CorrectPAnswer: mediatesPinteractionsPbetweenPGPCPandPunderlyingPrbcPskeleton
(gerbich)
Adducin
CorrectPAnswer: interactsPwithPdimericPBandP3P(associatedPwithPGPC)
ImportantPforPmaintainingPmembranePstability
Spectrin
CorrectPAnswer: majorPcomponentPofPunderlyingPskeleton
consistsPofP2Psubunits:PalphaP&Pbeta
ATPPsourcePforPRBCs
CorrectPAnswer: 90%PfromPGlycolysisP(Embden-MeyerhoffPpathway)
10%PfromPpentosePphosphatePpathway
MethemoglobinPReductasePPathway
CorrectPAnswer: necessaryPtoPmaintainPhemePironPinPferrousP(Fe2+)Pstate
2
,DeficiencyPcausesPaccumulationPofPmethemoglobin,PnonfunctionalPfromPofPHgb
LeuberingPRapaportPShunt
CorrectPAnswer: permitsPaccumulationPofP2,3-DPG
AllowsPrbcPtoPregulatePO2PtransportPduringPhypoxia
Embden-MeyerhoffPPathway
CorrectPAnswer: WholePanaerobicPglycolysisPpathwayPtakenPbyPrbc
generatesP90%PofPATPPneededPforPrbc
"TensePform"PofPHgb
CorrectPAnswer: DEOXYGENATED
wideningPofPbeta-chain
lowerPaffinityPforPO2
expelsP2,3-DPG
"RelaxedPform"PofPHgb
CorrectPAnswer: OXYGENATED
beta-chainPpulledPtogether
higherPaffinityPforPO2
expelsP2,3-DPG
"ShiftPRight"
3
, CorrectPAnswer: higherPP50Pvalue
decreasedPpHP(increasedPH+Pion),Pacidosis
increasedP2,3-DPG
higherPtemperature
highPpCO2
SeenPinPcompensatedPanemia/Pexercise
"ShiftPLeft"
CorrectPAnswer: lowerPP50Pvalue
increasedPpHP(decreasedPH+Pion),Palkalosis
decreasedP2,3-DPG
decreasedPATP
lowerPtemperatures
lowPpCO2
increasePK+
SeenPinPstoragePofPRBC
CompensatedPAnemiaPphysiologicPreactions
CorrectPAnswer: Increased:
-CardiacPoutputP(heartPrate,PstrokePvolume)
- BloodPflowP(vasodilation,Pshunting)
4
