p p p p p p p p
Latest Update 2024.
p p p
Allpaminopacidsparepbasedpuponpthepsamepgeneralpstructurepwhichpincludesp-pANSWERp-
panpalphapcarbon,panpaminopgroup,papcarboxylpgrouppandpapRpgroup
Thereparep4pdifferentpsubstituentspattachedptopthepalpha-carbon,pthuspmostpaminopacidspareppppp .
ispthe
onlypexceptionpbecausepitspRpgrouppispH.p-pANSWERp-pchiral;pgLYCINE
p
Aminopacidsphaveptwoppossible -pANSWERp-pstereoisomers
Enantiomersparepapparticularptypepofpstereoisomerspthatpare -pANSWERp-
pmirrorpimagespofponepanother
Aminopacidspcanpbepeither (exceptpglycine)p-pANSWERp-pDporpLp-penantiomers
Proteinsparepmadepfrom aminopacidsp-pANSWERp-pL
D-paminopacidsparepfoundpin -pANSWERp-
pbacterialpcellpwallspandpsomepantibioticspbutpareprelativelyprarepinpnature
Hydrophobicp(nonpolar)p-pANSWERp-p-Alanine
-Valine
-Leucine
-Isoleucine
-Proline
- Methionine
pg.p1
,- Phenylalanine
- Tryptophan
-Glycine
Polar,punchargedp-pANSWERp-p-Serine
- Threonine
-Cysteine
- Tyrosine
- Asparagine
-Glutamine
Polar,pchargedp-pANSWERp-p-Asparticpacid
-Glutamicpacid
- Lysine
- Arginine
- Histidine
Organismspthatpcanpmakepallpofpthep20paminopacidsp-pANSWERp-pbacteria,pyeast,pandpplants
Somepaminopacidsparepmadepdirectlypfrompcommonpmetabolicpintermediates..palaninepispmadepfrom -
pANSWERp-ppyruvate
Somepaminopacidsparepmadepaspproductspfromplongpandpcomplexppathways..paromaticpaminopacidspfro
mpthe -pANSWERp-pshikimicpacidppathway
Thepessentialpaminopacidsp-pANSWERp-p1.pArginine
2. Histidine
3. Isoleucine
4. Leucine
pg.p2
, 5. Lysine
6. Methionine
7. Phenylalanine
8. Threonine
9. Tryptophan
10. Valine
Pathwayspleadingptopessentialpaminopacidsparepgoodptargetspfor -pANSWERp-pherbicides
Glyphosphatep(Roundup)pispanpinhibitorpof ,panpenzymepofpthepshikimicpacidppathwayp-pANSWERp-
pEPSPpsynthase
Glyphosphatepblocks -pANSWERp-pBlockspthepproductionpofparomaticpaminopacids
Ascorbicpacidp(vitaminpC)pisprequiredpforpthepproductionpofp-pANSWERp-
pHydroxyprolinepandphydroxylysine,pbothpofpwhichparepfoundpinpconnectiveptissue
ApdeficiencypinpVitaminpCpispknownpas -pANSWERp-pscurvy
Acidsparepproton ,pandpbasesparepproton -pANSWERp-pdonors,pacceptors
Acidspdissociatepinto andpapconjugate -pANSWERp-pprotons,pbase
Basespassociatepwith topbecomeptheirpconjugate -pANSWERp-pprotons,pacids
Whyparepacid/baseppropertiespimportant?p-pANSWERp-
pBecausepmanypbiochemicalpcompoundsparepeitherpacidsporpbasesporpbothptheypcanpinfluenceptheprelativepa
bundancepofpprotonspinpthepcell
Similarly,ptheprelativepcontentpofpprotonsp(H+)pinpsolutionpdictatesppHpwhichpinpturnpdictatespthepionizationps
tatepofpbiologicalpmolecules.
pg.p3