Pharmacology and Pharmacotherapeutics
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Correct| Grade A+ | Latest 2025/2026
MN 553 unit 1
when a medication is added to a regimen for a synergistic effect the
combined effect of the drug is;
Correct Answer - Greater than the sum of the effects of each drug
individually
which of the following statements about bio availability is true
- Correct Answer - Bio availability issues are especially important for
drugs with narrow therapeutic ranges or sustained release mechanisms
which of the following statements about the major distribution barriers
(blood brain or fetal placental) is true?
- Correct Answer - The blood brain barrier slows the entry of many
drugs into and from brain cells
drugs are metabolized mainly by the liver be a phase 1 or phase 2
reactions. The purpose of both of these types of reactions is to;
- Correct Answer - Change drug molecules to a form that an excretory
organ can excrete
once they have metabolized by the liver the metabolites may be;
,- Correct Answer - All of the above
all drugs continue to act in the body until they are changed or excreted.
the ability of the body to excrete drugs via the renal system would be
increased by;
- Correct Answer - Unbinding a non-volatile drug from plasma proteins
The nurse practitioner Perspective authority is regulated by
- Correct Answer - The state board of nursing for each state
The benefits to the patient of having an advance practice registered
nurse prescriber include
- Correct Answer - Nurse is caring for the patient from a holistic
approach and include the patient and decision making regarding their
care
Clinical judgment in prescribing includes
- Correct Answer - Factoring in the cost to the patient of the medication
prescribed
Criteria for choosing an effective drug for a disorder include
- Correct Answer - Consulting nationally recognized guidelines for
disease management
Nurse practitioner practice may thrive under healthcare reform because
of - Correct Answer - The demonstrated ability of nurse practitioners to
control costs and improve patient outcomes
,A patient's nutritional intake and laboratory results reflect
hypoalbuminemia this is critical to prescribing because
- Correct Answer - Distribution of drugs to target tissue may be affected
drugs that have a significant first pass effect
- Correct Answer - Are rapidly metabolized by the liver and may have a
little if any desired action
The route of excretion of a volatile drug will likely be the
- Correct Answer - Lungs
Medroxyprogesterone is prescribed intramuscularly (IM) to create a
storage reservoir of the drug storage. Storage reservoirs:
- Correct Answer - Increase the length of time a drug is available and
active
The NP chooses to give cephalexin every eight hours based on
knowledge of the drugs:
- Correct Answer - Biological half-life
azithromycin dosing requires that the first days dosage be twice those of
the other four days of the prescription this is considered a loading dose.
A loading dose;
Correct Answer - Rapidly achieves drug levels in the therapeutic range
The point in time on the drug concentration curve that indicates the first
sign of a therapeutic effect is the;
- Correct Answer - Onset of action
, Phenytoin requires that a trough level be drawn. peak and trough levels
are done; - Correct Answer - To determine if a drug is in the therapeutic
range
A laboratory result indicates that the peak level of a drug is above the
minimum toxic concentration this means that
- Correct Answer - Concentration will produce an adverse response
Drugs that are receptor antagonist, such as beta blockers, may cause;
- Correct Answer - An exaggerated response if I abruptly discontinued
factors that affect gastric drug absorption include;
- Correct Answer - Lipid solubility of the drug
drugs administered via IV;
- Correct Answer - Begin distribution into the body immediately
Unit 2
A patients nutritional intake and lab results reflect hypoalbuminemia, this
is critical to prescribing because:
Distribution of the drug to target tissues may be effected
the solubility of the drug will not match the site of absorption
there will be less free drug available to give an effect
drugs bond to albumin and are readily excreted by the kidneys
- Correct Answer - Distribution of the drug to target tissue may be
effected