b b b b b bb
IENTIFIC BASIS AND PRACTICAL APPLICATIONS 4TH EDITION b b b b b b
Stahl's Essential Psychopharmacology b b
NeuroscientificbBasisbandbPracticalbApplicationsbTESTBANK/STUDYbGUIDE
Chapter 1 Chemical neurotransmissionb b b
MULTIPLE CHOICE b
1. A patient with depression mentions to the nurse, My mother says depression is a
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chemical disorder. What does she mean? The nurses response is based on the theor
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ythat depression primarily involves which of the following
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neurotransmitters?
a. Cortisol and GABA b b
b. COMT and glutamate b b
c. Monamine and glycine b b
d. Serotonin and norepinephrine b b
ANS: D b
One possible cause of depression is thought to involve one or more neurotransmitte
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rs.Serotonin and norepinephrine have been found to be important in the regulation
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of depression. There is no research to support that the other options play a significa
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nt role in the development of depression.
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2. A patient has experienced a stroke (cerebral vascular accident) that has resulte
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d in damage to the Broca area. Which evaluation does the nurse conduct to reinforce this
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diagnosis?
a. Observing the patient pick up a spoon b b b b b b
b. Asking the patient to recite the alphabet b b b b b b
c. Monitoring the patients blood pressure b b b b
d. Comparing the patients grip strength in both hands b b b b b b b
ANS: B b
Accidents or strokes that damage Brocas area may result in the inability to speak (i.e.
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, motor aphasia). Fine motor skills, blood pressure control, and muscle strength are n
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otcontrolled by the Broca area of the left frontal lobe. b b b b b b b b b
3. The patient diagnosed with schizophrenia asks why psychotropic medications a
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re always prescribed by the doctor. The nurses answer will be based on informatio
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n thatthe therapeutic action of psychotropic drugs is the result of their effect on:
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a. The temporal lobe; especially Wernickes area b b b b b
b. Dendrites and their ability to transmit electrical impulses b b b b b b b
c. The regulation of neurotransmitters especially dopamine
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d. The peripheral nervous system sensitivity to the psychotropic medications
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,ANS: C b
Medications used to treat psychiatric disorders operate in and around the synaptic cle
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ftand have action at the neurotransmitter level, especially in the case of schizophreni
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a, on dopamine. The Wernickes area, dendrite function, or the sensitivity of the perip
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heral nervous system are not relevant to either schizophrenia or psychotropic medica
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tions.
4. A student nurse mutters that it seems entirely unnecessary to have to struggle w
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ithunderstanding the anatomy and physiology of the neurologic system. The men b b b b b b b b b b
tor would base a response on the understanding that it is:
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Necessary but generally for psychiatric nurses who focus primarily onbehaviora b b b b b b b b b
a. l interventions b
A complex undertaking that advance practice psychiatric nurses frequently usei
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b. n their practice b b
Important primarily for the nursing assessment of patients with braintraumacaus b b b b b b b b b
c. ed cognitive symptoms b b
Necessary for planning psychiatric care for all patients especially thoseexperien b b b b b b b b b
d. cing psychiatric disorders b b
ANS: D b
Nurses must understand that many symptoms of psychiatric disorders have a neuro
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logic basis, although the symptoms are manifested behaviorally. This understandin
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g facilitates effective care planning. The foundation of knowledge is notused exclu
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sively by advanced practice psychiatric nurses nor is it relevant for only behavior th
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erapies or brain trauma since dealing with the results of normal and abnormal brain
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function is a responsibility of all nurses providing all types of care tothe psychiatric
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patient.
5. A patient asks the nurse, My wife has breast cancer. Could it be caused by he
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rchronic depression? Which response is supported by research data?
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a. Too much stress has been proven to cause all kinds of cancer.
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b. There have been no research studies done on stress and disease yet.
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c. Stress does cause the release of factors that suppress the immune system.
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d. There appears to be little connection between stress and diseases of the body
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ANS: C b
Research indicates that stress causes a release of corticotropin-
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releasing factors that suppress the immune system. Studies indicate that psychiatric
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disorders such as mooddisorders are sometimes associated with decreased function
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ing of the immune system.Research does not support a connection between many c
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ancers and stress. There is a significant amount of research about stress and the bod
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y.
Research has shown that there are some connections between stress and physical di
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sease.
,6. A patient who has a parietal lobe injury is being evaluated for psychiatric reh
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abilitation needs. Of the aspects of functioning listed, which will the nurse ident
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ifyas a focus of nursing intervention?
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a. Expression of emotion b b
b. Detecting auditory stimuli b b
c. Receiving visual images b b
d. Processing associations b
ANS: D b
The parietal lobe is responsible for associating and processing sensory information th
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at allows for functions such as following directions on a map, reading a clock, dressi
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ng self, keeping appointments, and distinguishing right from left. Emotional express
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ion is associated with frontal lobe function. Detecting auditory stimuli is a temporal l
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obe function. Receiving visual images is related to occipital lobe function.
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7. At admission, the nurse learns that some time ago the patient had an infarct in th
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eright cerebral cortex. During assessment, the nurse would expect to find that the
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patient:
a. Demonstrates major deficiencies in speech b b b b
b. Is unable to effectively hold a spoon in the left hand
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c. Has difficulty explaining how to go about using the telephone
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d. Cannot use his right hand to shave himself or comb his own hair b b b b b b b b b b b b
ANS: B b
The cerebral hemispheres are responsible for functions such as control of muscles. T
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he right hemisphere mainly controls the motor and sensory functions on the left side
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of the body. Damage to the right side would result in impaired function on the left sid
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e of the body. The motor cortex controls voluntary motor activity. Brocas area contro
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ls motor speech. Cognitive functions are attributed to the association cortex.
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The right side of the bodys motor activity is controlled by the left cerebral cortex.
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8. A patient with chronic schizophrenia had a stroke involving the hippocampus. T
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hepatient will be discharged on low doses of haloperidol. The nurse will need to indi
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vidualize the patients medication teaching by:
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a. Including the patients caregiver in the education b b b b b b
b. Being careful to stress the importance of taking the medication as prescribed
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Providing the education at a time when the patient is emotionally calm andrelaxe
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c. d
Encouraging the patient to crush or dissolve the medication to help withswallowi
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d. ng
ANS: A b
, The hippocampus plays a major role in short-
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term memory and, hence, in learning. Taking the medication as prescribed and pro
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viding the education at a time when the patient is calm and relaxed is information or
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considerations that all patients should begiven. The medication does not necessaril
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y need to be crushed or dissolved since the stroke would not have caused difficulty
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with swallowing.b
9. The physician tells the nurse, The medication Im prescribing for the pati
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ent enhances the g-
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aminobutyric acid (GABA) system. Which patient behavior willprovide ev
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idence that the medication therapy is successful?
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a. The patient is actively involved in playing cards with other patients.
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b. The patient reports that, I dont feel as anxious as I did a couple of days ago.
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c. The patient reports that both auditory and visual hallucinations have decrease
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d.
d. The patient says that, I am much happier than before I came to the hospital.
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ANS: B b
GABA is the principle inhibitory neurotransmitter. The medication should provide a
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nantianxiety effect. Alertness, psychotic behaviors, and mood elevation are not gene
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rally affected by g-aminobutyric acid.
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10. The patients family asks whether a diagnosis of Parkinsons disease creates a
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n increased risk for any mental health issues. What question would the nurse ask
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btoassess for such a comorbid condition?b b b b b
a. Has your father exhibited any signs of depression? b b b b b b b
b. Does your father seem to experience mood swings? b b b b b b b
c. Have you noticed your father talking about seeing things you cant see?
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d. Is your dad preoccupied with behaviors that he needs to repeat over and over?
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ANS: A b
Serotonin and its close chemical relatives, dopamine and norepinephrine, are the ne
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urotransmitters that are most widely involved in various forms of depression. Most
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researchers agree that the immediate cause of parkinsonism is a deficiency of dopa
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mine and so a patient with Parkinsons disease should be monitored for depression,
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The other mental health disorders (bipolar disorder, hallucinations, and obsessive c
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ompulsive disorder) have not been connected to Parkinsons disease.
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11. Which explanation for the prescription of donepezil (Aricept) would the n
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urseprovide for a patient in the early stage of Alzheimers disease?
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a. It will increase the metabolism of excess GABA.
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b. Excess dopamine will be prevented from attaching to receptor sites. b b b b b b b b b
c. Serotonin deficiency will be managed through a prolonged reuptake period. b b b b b b b b b
d. The acetylcholine deficiency will be managed by inhibiting cholinesterase.
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ANS: D b