TEST BANK m
Tietz Fundamentals Of
m m
CLINICAL CHEMISTRY AND
m m m
MOLECULAR DIAGNOSTICS m
7th Edition By Carl A. Burtis
m m m m m
TEST BANK m
,TietzmFundamentalsmof mClinicalmChemistrymandmMolecularmDiagnosticsm7thm EditionmTestmBank
Tablemof mcontents:
I.m Principlesm Ofm Laboratorym Medicine
Chapterm1.mClinicalmChemistry,mMolecularmDiagnostics,mand mLaboratorymMedicine
Chapterm2.mSelectionmand mAnalyticalmEvaluationmof mMethodsm—mWithmStatisticalmTechniques
Chapterm3.mClinicalmEvaluationmof mMethods
Chapterm4.mEvidence-Based mLaboratorymMedicine
Chapterm5.mEstablishment mand mUsemof mReferencemValues
Chapterm6.mSpecimenmCollection,mProcessing,mand mOthermPreanalyticalmVariables
Chapterm7.mQualitymManagement
II.m Analyticalm Techniquesm Andm Instrumentation
Chapterm8.mPrinciplesmof mBasicmTechniquesmand mLaboratorymSafety
Chapterm9.mOpticalmTechniques
Chapterm10.mElectrochemistrymand mChemicalmSensors
Chapterm11.mElectrophoresis
Chapterm12.mChromatography
Chapterm13.mMassmSpectrometry
Chapterm14.mEnzymemand mRatemAnalyses
Chapterm15.mImmunochemicalmTechniques
Chapterm16mAutomation
Chapterm17.mPoint-of-CaremInstrumentation
III.m Analytes
Chapterm18.mAminomAcids,mPeptides,mand mProteins
Chapterm19.mSerummEnzymes
Chapterm20.mTumormMarkersmand mCancermGenes
Chapterm21.mKidneymFunctionmTestsm—mCreatinine,mGFR,mUrea,mand mUricmAcid
Chapterm22.mCarbohydrates
Chapterm23.mLipids,mLipoproteins,mApolipoproteins,mand mOthermCardiacmRiskmFactors
Chapterm24.mElectrolytesmand mBlood mGases
Chapterm25.mHormones
Chapterm26.m Catecholaminesmand mSerotonin
Chapterm27.m Vitamins,mTracemElements,mNutritionalmAssessment
Chapterm28.mHemoglobin,mIron,mand mBilirubin
Chapterm29.mPorphyrinsmand mPorphyrias
Chapterm30.mTherapeuticmDrugsmand mTheirmManagement
Chapterm31.mClinicalmToxicology
Chapterm32.m ToxicmMetals
IV.m Pathophysiology
Chapterm33.mDiabetes
,Chapterm34.m CardiovascularmDisease
Chapterm35.mKidneymDisease
Chapterm36.m Physiologymand mDisordersmof mWater,mElectrolyte,mand mAcid-BasemMetabolism
Chapterm37.m LivermDisease
Chapterm38.m Gastrointestinalmand mPancreaticmDiseases
Chapterm39.m Disordersmof mBonemand mMineralmMetabolism
Chapterm40.m Disordersmof mthemPituitarymGland
Chapterm41.m Disordersmof mthemAdrenalmCortex
Chapterm42.m Thyroid mDisorders
Chapterm43.m Reproduction-Related mDisorders
Chapterm44.m Pregnancymand mPrenatalmTesting
Chapterm45.m NewbornmScreeningmand mInbornmErrorsmof mMetabolism
Chapterm46.mPharmacogenetics
V.m Molecularm Diagnostics
Chapterm47.mPrinciplesmof mMolecularmBiology
Chapterm48.mNucleicmAcid mTechniquesmand mApplications
Chapterm49.mGenomesmand mNucleicmAcid mAlterations
, Tietzm Fundamentalsm ofm Clinicalm Chemistrym andmMolecularDiagnostics,m 7em Burtism Testm Bank
Chapterm01:mClinicalmChemistry,mMolecularmDiagnostics,mandmLaboratorymMedicineTestmB
ank
MULTIPLEmCHOICE
1. Anmindividualmworkingminmamclinicalmchemistrymlaboratorymismmarried mtomamsalesmrepresentativ
emwhomworksmformamcompanymthat msellsmchemistrymlaboratorymsupplies.mWhen mthemlaboratorym
managermrequestsmamlist mof mneeded msupplies,mcost mof msupplies,mand mvendors,mthismindividualmo
nlymrecommendsmthemspouse’smcompanymasmthemvendor.mThism ismconsidered mtombema(n):
a. accountingmissue.
b. possiblemconflict mof minterest.
c. maintenancemof mconfidentialitymissue.
d. problemmwithmresourcemallocation.
ANS:m B
Concernmhasmbeenmraised movermtheminterrelationshipsmbetweenmpractitionersminmthemmedicalmfield
mand mcommercialmsuppliersmof mdrugs,mdevices,mequipment,metc.,mtomthemmedicalmprofession.
Similarly,mrelationshipsmhavembeen mscrutinized mbetweenmclinicalmlaboratorians mand mmanufactur
ersmand mprovidersmof mdiagnosticmequipment mand msupplies.mThesemconcernsmled mthemNationalmIns
titutesmof mHealthm(NIH)minm1995mtomrequiremofficialminstitutionalmreview mof mfinancialmdisclosure
mbymresearchersmand mmanagement mof msituationsminmwhichmdisclosuremindicatesmpotentialmconflict
smof minterest.
DIF: 1 REF:m Pagem4-5 OBJ:m 6 m|m7
2. A mpatient mvisitsmhermphysicianmstatingmthat mhermprescribed mpainkiller mis mnot mworkingmtomredu
cemthempainmfollowingmhermrecent msurgery.mAmfriend mof mthempatient mclaimsmthat mthemsamempai
nkillerm“worked mwonders”mtomreducemhermpainmaftermthemsamemsurgery.mThemphysicianmstates
mthat mthemdifferenceminmthemeffect mof mthemdrugmmight mbemcaused mby
,mwhichmismstudied minmpharmacog
enetics.
a. epidemiology
b. anminherited mdisease
c. amconflict mof minterest
d. amgeneticmvariationminmdrug-metabolizingmenzymes
ANS:m D
Pharmacogeneticsmismthemstudymof mthemgeneticmvariationmof mdrugmmetabolismmbetweenmindi
viduals.
DIF: 1 REF:m m Pagem3 OBJ:m 1
3. Johnmworksminmammolecularmdiagnosticsmlaboratorymand mreceivesmamblood msamplemthat mhasmt
hemnamemof mamclosemfriend mprinted monmthembar-
coded mlabel.mThemgeneticmtest mthat mismordered monmthemfriend’smsamplemwould mprovidemdiagno
sticminformationmabout mamdisordermthat mhasmampoormprognosis,mand mthemtest mismusuallymperfor
med mbymJohn.mHemasksmamfellow memployeemtomanalyzemthemsamplemformhimmand mnot mdivulgem
themresults.mThismethicalmissuemconcerns:
a. confidentialitymof mpatient mgeneticmand mmedicalminformation.
b. amconflict mof minterest.
c. resourcemallocation.
d. diagnosticmaccuracy.
Tietz Fundamentals Of
m m
CLINICAL CHEMISTRY AND
m m m
MOLECULAR DIAGNOSTICS m
7th Edition By Carl A. Burtis
m m m m m
TEST BANK m
,TietzmFundamentalsmof mClinicalmChemistrymandmMolecularmDiagnosticsm7thm EditionmTestmBank
Tablemof mcontents:
I.m Principlesm Ofm Laboratorym Medicine
Chapterm1.mClinicalmChemistry,mMolecularmDiagnostics,mand mLaboratorymMedicine
Chapterm2.mSelectionmand mAnalyticalmEvaluationmof mMethodsm—mWithmStatisticalmTechniques
Chapterm3.mClinicalmEvaluationmof mMethods
Chapterm4.mEvidence-Based mLaboratorymMedicine
Chapterm5.mEstablishment mand mUsemof mReferencemValues
Chapterm6.mSpecimenmCollection,mProcessing,mand mOthermPreanalyticalmVariables
Chapterm7.mQualitymManagement
II.m Analyticalm Techniquesm Andm Instrumentation
Chapterm8.mPrinciplesmof mBasicmTechniquesmand mLaboratorymSafety
Chapterm9.mOpticalmTechniques
Chapterm10.mElectrochemistrymand mChemicalmSensors
Chapterm11.mElectrophoresis
Chapterm12.mChromatography
Chapterm13.mMassmSpectrometry
Chapterm14.mEnzymemand mRatemAnalyses
Chapterm15.mImmunochemicalmTechniques
Chapterm16mAutomation
Chapterm17.mPoint-of-CaremInstrumentation
III.m Analytes
Chapterm18.mAminomAcids,mPeptides,mand mProteins
Chapterm19.mSerummEnzymes
Chapterm20.mTumormMarkersmand mCancermGenes
Chapterm21.mKidneymFunctionmTestsm—mCreatinine,mGFR,mUrea,mand mUricmAcid
Chapterm22.mCarbohydrates
Chapterm23.mLipids,mLipoproteins,mApolipoproteins,mand mOthermCardiacmRiskmFactors
Chapterm24.mElectrolytesmand mBlood mGases
Chapterm25.mHormones
Chapterm26.m Catecholaminesmand mSerotonin
Chapterm27.m Vitamins,mTracemElements,mNutritionalmAssessment
Chapterm28.mHemoglobin,mIron,mand mBilirubin
Chapterm29.mPorphyrinsmand mPorphyrias
Chapterm30.mTherapeuticmDrugsmand mTheirmManagement
Chapterm31.mClinicalmToxicology
Chapterm32.m ToxicmMetals
IV.m Pathophysiology
Chapterm33.mDiabetes
,Chapterm34.m CardiovascularmDisease
Chapterm35.mKidneymDisease
Chapterm36.m Physiologymand mDisordersmof mWater,mElectrolyte,mand mAcid-BasemMetabolism
Chapterm37.m LivermDisease
Chapterm38.m Gastrointestinalmand mPancreaticmDiseases
Chapterm39.m Disordersmof mBonemand mMineralmMetabolism
Chapterm40.m Disordersmof mthemPituitarymGland
Chapterm41.m Disordersmof mthemAdrenalmCortex
Chapterm42.m Thyroid mDisorders
Chapterm43.m Reproduction-Related mDisorders
Chapterm44.m Pregnancymand mPrenatalmTesting
Chapterm45.m NewbornmScreeningmand mInbornmErrorsmof mMetabolism
Chapterm46.mPharmacogenetics
V.m Molecularm Diagnostics
Chapterm47.mPrinciplesmof mMolecularmBiology
Chapterm48.mNucleicmAcid mTechniquesmand mApplications
Chapterm49.mGenomesmand mNucleicmAcid mAlterations
, Tietzm Fundamentalsm ofm Clinicalm Chemistrym andmMolecularDiagnostics,m 7em Burtism Testm Bank
Chapterm01:mClinicalmChemistry,mMolecularmDiagnostics,mandmLaboratorymMedicineTestmB
ank
MULTIPLEmCHOICE
1. Anmindividualmworkingminmamclinicalmchemistrymlaboratorymismmarried mtomamsalesmrepresentativ
emwhomworksmformamcompanymthat msellsmchemistrymlaboratorymsupplies.mWhen mthemlaboratorym
managermrequestsmamlist mof mneeded msupplies,mcost mof msupplies,mand mvendors,mthismindividualmo
nlymrecommendsmthemspouse’smcompanymasmthemvendor.mThism ismconsidered mtombema(n):
a. accountingmissue.
b. possiblemconflict mof minterest.
c. maintenancemof mconfidentialitymissue.
d. problemmwithmresourcemallocation.
ANS:m B
Concernmhasmbeenmraised movermtheminterrelationshipsmbetweenmpractitionersminmthemmedicalmfield
mand mcommercialmsuppliersmof mdrugs,mdevices,mequipment,metc.,mtomthemmedicalmprofession.
Similarly,mrelationshipsmhavembeen mscrutinized mbetweenmclinicalmlaboratorians mand mmanufactur
ersmand mprovidersmof mdiagnosticmequipment mand msupplies.mThesemconcernsmled mthemNationalmIns
titutesmof mHealthm(NIH)minm1995mtomrequiremofficialminstitutionalmreview mof mfinancialmdisclosure
mbymresearchersmand mmanagement mof msituationsminmwhichmdisclosuremindicatesmpotentialmconflict
smof minterest.
DIF: 1 REF:m Pagem4-5 OBJ:m 6 m|m7
2. A mpatient mvisitsmhermphysicianmstatingmthat mhermprescribed mpainkiller mis mnot mworkingmtomredu
cemthempainmfollowingmhermrecent msurgery.mAmfriend mof mthempatient mclaimsmthat mthemsamempai
nkillerm“worked mwonders”mtomreducemhermpainmaftermthemsamemsurgery.mThemphysicianmstates
mthat mthemdifferenceminmthemeffect mof mthemdrugmmight mbemcaused mby
,mwhichmismstudied minmpharmacog
enetics.
a. epidemiology
b. anminherited mdisease
c. amconflict mof minterest
d. amgeneticmvariationminmdrug-metabolizingmenzymes
ANS:m D
Pharmacogeneticsmismthemstudymof mthemgeneticmvariationmof mdrugmmetabolismmbetweenmindi
viduals.
DIF: 1 REF:m m Pagem3 OBJ:m 1
3. Johnmworksminmammolecularmdiagnosticsmlaboratorymand mreceivesmamblood msamplemthat mhasmt
hemnamemof mamclosemfriend mprinted monmthembar-
coded mlabel.mThemgeneticmtest mthat mismordered monmthemfriend’smsamplemwould mprovidemdiagno
sticminformationmabout mamdisordermthat mhasmampoormprognosis,mand mthemtest mismusuallymperfor
med mbymJohn.mHemasksmamfellow memployeemtomanalyzemthemsamplemformhimmand mnot mdivulgem
themresults.mThismethicalmissuemconcerns:
a. confidentialitymof mpatient mgeneticmand mmedicalminformation.
b. amconflict mof minterest.
c. resourcemallocation.
d. diagnosticmaccuracy.
