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est Bank /Pharmacology Test Bank
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1. A nurse working in radiology administers iodine to a patient who is having a computed t
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omography (CT) scan. The nurse working on the oncology unit administers chemotherap
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y to patients who have cancer. At the Public Health Department, a nurse administers a m
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easles-mumps-rubella (MMR) vaccine to a 14-month-
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old child as a routine immunization. Which branch of pharmacology best describes the ac
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tions of all three nurses?
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a. Pharmacoeconomics
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b. Pharmacotherapeutics
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c. Pharmacodynamics
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d. Pharmacokinetics
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b. Pharmacotherapeutics
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Pharmacology is the study of the biologic effects of chemicals. Nurses are involved with c
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linical pharmacology or pharmacotherapeutics, which is a branch of pharmacology that d
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eals with the uses of drugs to treat, prevent, and diagnose disease. The radiology nurse i
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s administering a drug to help diagnose a disease. The oncology nurse is administering a
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drug to help treat a disease. Pharmacoeconomics includes any costs involved in drug the
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rapy. Pharmacodynamics involves how a drug affects the body and pharmacokinetics is
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how the drug acts on the body.
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2.A physician has ordered intramuscular (IM) injections of morphine, a narcotic, every 4 h
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ours as needed for pain in a motor vehicle accident victim. The nurse is aware this drug h
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as a high abuse potential. Under what category wound morphine be classified?
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a. Schedule I
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b. Schedule II
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c. Schedule III
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d. Schedule IV
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b. Schedule II
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Narcotics with a high abuse potential are classified as Schedule II drugs because of seve
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re dependence liability. Schedule I drugs have high abuse potential and no accepted med
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ical use. Schedule III drugs have a lesser abuse potential than II and an accepted medica
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l use. Schedule IV drugs have low abuse potential and limited dependence liability.
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3.When involved in phase III drug evaluation studies, what responsibilities would the nurs
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e have?
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a. Working with animals who are given experimental drugs.
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b. Choosing appropriate patients to be involved in the drug study.
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c. Monitoring and observing patients closely for adverse effects.
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d. Conducting research to determine effectiveness of the drug.
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c. Monitoring and observing patients closely for adverse effects.
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Phase III studies involve use of a drug in a vast clinical population in which patients are a
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sked to record any symptoms they experience while taking the drugs. Nurses may be res
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ponsible for helping collect and analyze the information to be shared with the Food and D
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rug Administration (FDA) but would not conduct research independently because nurses
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do not prescribe medications. Use of animals in drug testing is done in the preclinical trial
,Pharm Test Bank/ Introduction To Drugs T
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est Bank /Pharmacology Test Bank
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s. Select patients who are involved in phase II studies to participate in studies where the
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participants have the disease and drug is intended to treat. These patients are monitored
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closely for drug action and adverse effects. Phase I studies involve healthy human volunt
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eers who are usually paid for their participation. Nurses may observe for adverse effects
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and toxicity.
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4.What concept is considered when generic drugs are substituted for brand name drugs?
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a. Bioavailability
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b. Critical consentration
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c. Distribution
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d. Half-life
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a. Bioavailability
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.Bioavailability is the portion of a dose of a drug that reaches the systemic circulation and
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is available to act on body cells. Binders used in a generic drug may not be the same as t
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hose used in the brand name drug. Therefore, the way the body breaks down and uses th
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e drug may differ, which may eliminate a generic drug substitution. Critical concentration i
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s the amount of a drug that is needed to cause a therapeutic effect and should not differ b
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etween generic and brand name medications. Distribution is the phase of pharmacokineti
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cs, which involves the movement of a drug to the body's tissues and is the same in generi
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c and brand name drugs. A drug's half-
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life is the time it takes for the amount of drug to decrease to half the peak level, which sho
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uld not change when substituting a generic medication.
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5.A nurse is assessing the patient's home medication use. After listening to the patient list
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current medications, the nurse asks which priority question?
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a. Do you take any generic medications?
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b. Are any of these medications orphan drugs?
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c. Are these medications safe to take during pregnancy?
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d. Do you take any over-the-counter medications?
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d. Do you take any over-the-counter medications?
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.It is important for the nurse to specifically question use of over-the-
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counter medications because patients may not consider them important. The patient is u
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nlikely to know the meaning of orphan drugs unless they too are health care providers. Sa
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fety during pregnancy, use of a generic medication, or classification of orphan drugs are t
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hings the patient would be unable to answer but could be found in reference books if the
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nurse wishes to research them.
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6.After completing a course on pharmacology for nurses, what will the nurse know?
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a. Everything necessary for safe and effective medication administration.
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b. Current pharmacologic therapy; the nurse will not require ongoing education for 5 year
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s.
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c. General drug information; the nurse can consult a drug guide for specific drug informati
on.
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d. The drug actions that are associated with each classification of medication.
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c. General drug information; the nurse can consult a drug guide for specific drug informati
on.
,Pharm Test Bank/ Introduction To Drugs T
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est Bank /Pharmacology Test Bank
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.After completing a pharmacology course nurses will have general drug information need
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ed for safe and effective medication administration but will need to consult a drug guide fo
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r specific drug information before administering any medication. Pharmacology is consta
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ntly changing, with new drugs entering the market and new uses for existing drugs identifi
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ed. Continuing education in pharmacology is essential to safe practice. Nurses tend to be
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come familiar with the medications they administer most often, but there will always be a
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need to research new drugs and also those the nurse is not familiar with because no nurs
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e knows all medications.
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7.A nurse is instructing a pregnant patient concerning the potential risk to her fetus from a
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Pregnancy Category B drug. What would the nurse inform the patient?
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a. Adequate studies in pregnant women have demonstrated there is no risk to the fetus.
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b. Animal studies have not demonstrated a risk to the fetus, but there have been no adeq
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uate studies in pregnant women.
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c. Animal studies have shown an adverse effect on the fetus, but there are no adequate s
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tudies in pregnant women.
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d. There is evidence of human fetal risk, but the potential benefits from use of the drug m
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ay be acceptable despite potential risks.
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b. Animal studies have demonstrated a risk to the fetus, but there have been no adequate
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studies in pregnant women.
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Category B indicates that animal studies have not demonstrated a risk to the fetus. Howe
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ver, there have not been adequate studies in pregnant women to demonstrate risk to a fet
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us during the first trimester of prenancy and no evidence of risk in later trimesters. Catego
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ry A indicates that adequate studies in pregnant women have not demonstrated a risk to t
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he fetus in the first trimester or in later trimesters. Category C indicates that animal studie
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s have shown an adverse effect on the fetus, but no adequate studies in humans. Catego
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ry D reveals evidence of human fetal risk, but the potential benefits from the use of the dr
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ugs in pregnant women may outweigh potential risks.
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8.Discharge planning for patients leaving the hospital should include instructions on the u
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se of over-the-
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counter (OTC) drugs. Which comment by the patient would demonstrate a good understa
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nding of OTC drugs?
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a. OTC drugs are safe and do not cause adverse effects if taken properly.
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b. OTC drugs have been around for years and have not been tested by the Food and Dru
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g Administration (FDA).
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c. OTC drugs are different from any drugs available by prescription and cost less.
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d. OTC drugs could cause serious harm if not taken according to directions.
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d. OTC drugs could cause serious harm if not taken according to direction.
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.It is important to follow package directions because OTCs are medications that can caus
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e serious harm if not taken properly. OTCs are drugs that have been determined to be saf
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e when taken as directed; however, all drugs can produce adverse effects even when tak
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en properly. They may have originally been prescription drugs that were tested by the FD
, Pharm Test Bank/ Introduction To Drugs T
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est Bank /Pharmacology Test Bank
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A or they may have been grandfathered in when the FDA laws changed. OTC education
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should always be included as a part of the hospital discharge instructions.
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9.What would be the best source of drug information for a nurse?
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a. Drug Facts and Comparisons
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b. A nurse's drug guide
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c. A drug package insert
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d. The Physicians' Drug Reference (PDR)
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b. A nurse's drug guide
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10.The nurse is preparing to administer a medication from a multidose bottle. The label is
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torn and soiled but the name of the medication is still readable. What is the nurse's priorit
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y action?
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a. Discard the entire bottle and contents and obtain a new bottle.
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b. Find the drug information and create a new label for the bottle.
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c. Ask another nurse to verify the contents of the bottle.
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d. Administer the medication if the name of the drug can be clearly read.
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a. Discard the entire bottle and contents and obtain a new bottle.
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When the drug label is soiled obscuring some information the safest action by the nurse i
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s to discard the bottle and contents because drug labels contain a great deal of important
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information, far more than just the name of the drug. Concentration of the drug, expiration
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date, administration directions, and precautions may be missing from the label and so pu
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t the patient at risk. Looking up drug information in a drug handbook or consulting with an
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other nurse will not supply the expiration date or concentration of medicine. Be safe and d
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iscard the bottle and its contents.
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Select all that apply.
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11.What aspects of pharmacology does a nurse study?
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a. Chemical pharmacology.
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b. Molecular pharmacology.
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c. Impact of drugs on the body.
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d. The body's response toa drug.
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e. Adverse and anticipated drug effects.
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c. Impact of drugs on the body.
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d. The body's response to a drug.
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e. Adverse and anticipated drug effects.
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Nurses study pharmacology from a pharmacotherapeutic level, which includes the effect
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of drugs on the body, the body's response to drugs, and both expected and unexpected d
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rug effects. Chemical and molecular pharmacology are not included in nursing pharmacol
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ogy courses.
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The nurse, providing patient teaching about home medication use to an older adult, expla
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ins that even when drugs are taken properly they can produce negative or unexpected eff
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ects. What are these negative or unexpected effects called?
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a. Teratogenic effects.
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b. Toxic effects.
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c. Adverse effects.