Test bank for Davis Advantage for Pathophysiology In
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troductory Concepts and Clinical Perspectives
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Chapter m1,mThemCellminmHealthmandmIllness
MultiplemChoice
Identifymthemchoicemthatmbestmcompletesmthemstatementmormanswersmthemquestion.
1. Whichmstatement mregardingmthemsodium–potassiummpumpmismcorrect?
1. Themcell’smplasmammembranemismmorem solublemtomsodiummionsmthanmpotassiummions.
2. Themconcentrationmof msodiummionsmshould mbemhigherminsidemthemcellmcompartment.
3. Themconcentrationmof mpotassiummionsmshould mbemhighermoutsidemthemce
llmcompartment.
4. Themactivemtransport minvolvesmpumpingmout mthreemsodiummionsmand mpumpingminmtwo
potassiummions.
2. Inmthemabsencemof moxygen,mwhichmcellularmfunctionmcreatesmthemsamemamount mof menergymasmismcreated
minmthempresencemof moxygen?
1. Dissipationmof mpyruvicmacid
2. Initiationmof mthemcitricmacid mcycle
3. Activationmof macetyl-coenzymemA
4. Creationmof macidosismviamlacticmacid
3. How mmanymadenosinemtriphosphatesm(ATPs)maremproduced minmaerobicmenergymmetabolism?
1.m m 2
2.m m 3
3.m m 34
4.m m 53
4. Whichmcellmorganellesmdifferminmtheirmnumbermaccordingmtomthemcell’smenergymneeds?
1. Ribosomes
2. Mitochondria
3. Ribonucleicmacids
4. Deoxyribonucleicmacids
5. Whichmoptionmbest msupportsmthemreasonmmoremenergymismproduced mwhenmampersonmismexercising?
1. Exercisemcausesmanmincreaseminmthemsynthesismof mprotein.
2. Theremismanmincreaseminmthemproductionmof mpyruvicmacid minmthemcells.
3. Themconversionmof mpyruvicmacid mtomlacticmacid mismincreased mbymexercise.
4. Musclemcellsmhavemmoremmitochondriamtommeet menergymdemands.
6. Whenmdoesmribosomalmproteinmsynthesismcease?
1. Duringmendoplasmicmreticulummstress
2. Duringmthemsynthesismof madenosinemtriphosphatem(ATP)
3. Duringmamseveremhypoxicmstate
4. Duringmthemprocessingmof mprohormone
7. Whichmcellularmorganellesmaremresponsiblemformpropellingmmucusmand minhaled mdebrismout mof mthemlungs?
1. Cilia
2. Microfilaments
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3. Secretorymvesicles
4. Endoplasmicmreticula
8.m m Whichmaremthemkeymproteinsminmthemcontractilemunitsmof mthemmusclemcells?
1. Actinmand mmyosin
2. Prohormonemand mtubulin
3. Tubulinmand mactin
4. Myosinmand mprohormone
9.m m WhichmdeficiencymcausesmTay–Sachsmdisease?
1. Proteasome
2. Peroxisome
3. Macrophage
4. Lysosomalmenzymes
m 10.m Whichmismamcharacteristicmof madrenoleukodystrophy?
1. Accumulationmof mganglioside
2. Cessationmof mribosomalmproteinmsynthesis
3. Accelerationmof mcellularmproteasomemactivity
4. Accumulationmof mlong-chainmfattymacidsminmthemnervousmsystem
m 11.m Whichmstatement mregardingmendoplasmicmreticulumm(ER)mstressmism correct?
1. DuringmERmstress,mproteinsmaremrapidlymdegraded.
2. DuringmERmstress,mlipidsmcannot mtravelmtomtheirmpropermintracellularmlocations.
3. DuringmERmstress,mlong-chainmfattymacidsmaccumulateminmthemnervousmsystem.
4. DuringmERmstress,mnondegraded msubstancesmaccumulateminmthemcells.
m 12.m Amclient mismdiagnosed mwithmtypem1mdiabetesmmellitus.mAt mamcellularmlevel,mwhichmfunctionmismlikelymt
ombeminvolved?
1. Inabilitymof mribosomesmtomproducemamspecificmtypemof mprotein
2. Incorrect mprocessingmof mamproteinmbymthemGolgimapparatus
3. Stagnationmof mampreviouslymdynamicmactionminmmicrotubules
4. Obstructionmof mthemsmoothmendoplasmicmreticulum
m 13.m Amnewbornmpatient mexhibitsmcharacteristicsmof mseveremphysicalmdeformities.mWhichmcellularmcompone
nt mismexamined mtomdeterminemthemcausemand mprobabilitymof mthemdiseasembeingmgeneticallymtransferred
?
1. TransfermRNA
2. RibosomalmRNA
3. Doublemhelixmof mDNA
4. MitochondrialmDNA
m 14.m Amhikermexperiencesmmusclempainmand macidosismwhilemascendingmammountainmduringmamlong,mst
eepmclimb.mWhichmismthemreasonmformthesemmanifestations?
1. Cellularmhypoxia
2. Autolysis
3. Heterolysis
4. Cellularmedema
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m 15.m m WhichmfactormprovidesmDNA mthemuniquemmolecularmabilitymtomreplicate?
1. Thempairingmof mnitrogenousmbases
2. Thempresencemof mpyrimidinembases
3. Thempresencemof mnucleotides
4. Themnitrogenousmbasemand mphosphatembond
m 16.m m How mmanymnitrogenousmbasesmcomposemamsinglemcodon?
1.m m 2
2.m m 3
3.m m 4
4.m m 5
m 17.m Whichmcomponentsmformmthemstructuremof mDNA?
1. Nucleotides
2. Aminomacids
3. Fattymacids
4. Phosphates
m 18.m m Whichmfactormismessentialminmordermformproteinmsynthesismtomoccur?
1. Free-standingmribosomesmwithinmthemcell
2. Proteinmblueprint mfrommthemcellmof mthemDNA
3. Specificminformationmfrommthemnucleusmof mthemcell
4. TransfermRNA mtommovemthemproteinmout mof mthemcell
m 19.m Tetracyclinemantibioticmismprescribed mformanmadult mclient mwithmchlamydiaminfection.mWhichmism
themmechanismmof mactionmof mthemdrug?
1. It mpreventsmthemreplicationmof mbacteria.
2. It maltersmthemconfigurationmof mbacterialmcytoplasm.
3. It minterferesmwithmthemfunctionmof mbacterialmribosomes.
4. It minhibitsmthemfunctionsmof mbacterialmmitochondria.
m 20.m m Wheremdoesmthemconversionmof mamprohormonemintomamhormonemtakemplace?
1. Inmthemribosomes
2. InmthemGolgimapparatus
3. Inmthemsecretorymgranules
4. Inmthemendoplasmicmreticulum
m 21.m Whichmismthemcell’sm“mastermmind”?
1. Nucleus
2. Ribosome
3. Golgimapparatus
4. Endoplasmicmreticulum
MultiplemResponse
Identifymonemormmoremchoicesmthatmbestmcomplete mthemstatementmormanswermthemquestion.
m 22.m m Whichmstatementsmregardingmthemmicrotubulesmaremtrue?mSelectmallmthatmapply.
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