PATHOPHYSIOLOGY EXAM 1 2023-2024 n n n
QUESTIONS AND ANSWERS. n n
An ordered photographic display of a set of chromosomes
n n n n n n n n
from a single cell is a(n):
n n n n n
A) metaphase spread. n
B) autosomal spread. n
C) karyotype.
D) anaphase spread. - ANSWER -c
n n n n
An error in which homologous chromosomes fail to separate
n n n n n n n n
during meiosis is termed:
n n n
A) aneuploidy.
B) nondisjunction.
C) polyploidy.
,D) anaplasia. - ANSWER -b n n n
A somatic cell that does not contain a multiple of 23
n n n n n n n n n n
chromosomes is called: n n
A) an aneuploid cell.
n n
B) a euploid cell.
n n
C) a polyploidy cell.
n n
D) a haploid cell. - ANSWER -a
n n n n n
A 20-year-old pregnant female gives birth to a stillborn child.
n n n n n n n n n
Autopsy reveals that the fetus has 92 chromosomes. Which
n n n n n n n n
of the following describes this condition?
n n n n n
A) Euploidy
B) Triploidy
C) Tetraploidy
D) Aneuploidy - ANSWER -c n n n
If a person is a chromosomal mosaic, the person may:
n n n n n n n n n
,A) be a carrier of the genetic disease.
n n n n n n
B) have a mild form of the genetic disease.
n n n n n n n
C) have two genetic diseases.
n n n
D) be sterile as a result of the genetic disease. - ANSWER -b
n n n n n n n n n n n
The most common cause of Down syndrome is:
n n n n n n n
A) paternal nondisjunction. n
B) maternal translocations. n
C) maternal nondisjunction. n
D) paternal translocations. - ANSWER -c
n n n n
Risk factors for Down syndrome include:
n n n n n
A) fetal exposure to mutagens in the uterus.
n n n n n n
B) increased paternal age. n n
C) family history of Down syndrome.
n n n n
D) pregnancy in women over age 35. - ANSWER -d
n n n n n n n n
, A 13-year-old girl has a karyotype that reveals an absent
n n n n n n n n n
homologous X chromosome with only a single X
n n n n n n n
chromosome present. Her condition is called: n n n n n
A) Down syndrome. n
B) Cri du chat syndrome.
n n n
C) Turner syndrome. n
D) Edward syndrome - ANSWER -c
n n n n
A child is diagnosed with cystic fibrosis. History reveals that
n n n n n n n n n
the child's parents are first cousins. Cystic fibrosis was most
n n n n n n n n n
likely the result of:
n n n
A) X inactivation.
n
B) genomic imprinting. n
C) consanguinity.
D) obligate carriers. - ANSWER -cn n n n
Joey, age 9, is admitted to a pediatric unit with Duchenne
n n n n n n n n n n
muscular dystrophy. He inherited this condition through a:
n n n n n n n
QUESTIONS AND ANSWERS. n n
An ordered photographic display of a set of chromosomes
n n n n n n n n
from a single cell is a(n):
n n n n n
A) metaphase spread. n
B) autosomal spread. n
C) karyotype.
D) anaphase spread. - ANSWER -c
n n n n
An error in which homologous chromosomes fail to separate
n n n n n n n n
during meiosis is termed:
n n n
A) aneuploidy.
B) nondisjunction.
C) polyploidy.
,D) anaplasia. - ANSWER -b n n n
A somatic cell that does not contain a multiple of 23
n n n n n n n n n n
chromosomes is called: n n
A) an aneuploid cell.
n n
B) a euploid cell.
n n
C) a polyploidy cell.
n n
D) a haploid cell. - ANSWER -a
n n n n n
A 20-year-old pregnant female gives birth to a stillborn child.
n n n n n n n n n
Autopsy reveals that the fetus has 92 chromosomes. Which
n n n n n n n n
of the following describes this condition?
n n n n n
A) Euploidy
B) Triploidy
C) Tetraploidy
D) Aneuploidy - ANSWER -c n n n
If a person is a chromosomal mosaic, the person may:
n n n n n n n n n
,A) be a carrier of the genetic disease.
n n n n n n
B) have a mild form of the genetic disease.
n n n n n n n
C) have two genetic diseases.
n n n
D) be sterile as a result of the genetic disease. - ANSWER -b
n n n n n n n n n n n
The most common cause of Down syndrome is:
n n n n n n n
A) paternal nondisjunction. n
B) maternal translocations. n
C) maternal nondisjunction. n
D) paternal translocations. - ANSWER -c
n n n n
Risk factors for Down syndrome include:
n n n n n
A) fetal exposure to mutagens in the uterus.
n n n n n n
B) increased paternal age. n n
C) family history of Down syndrome.
n n n n
D) pregnancy in women over age 35. - ANSWER -d
n n n n n n n n
, A 13-year-old girl has a karyotype that reveals an absent
n n n n n n n n n
homologous X chromosome with only a single X
n n n n n n n
chromosome present. Her condition is called: n n n n n
A) Down syndrome. n
B) Cri du chat syndrome.
n n n
C) Turner syndrome. n
D) Edward syndrome - ANSWER -c
n n n n
A child is diagnosed with cystic fibrosis. History reveals that
n n n n n n n n n
the child's parents are first cousins. Cystic fibrosis was most
n n n n n n n n n
likely the result of:
n n n
A) X inactivation.
n
B) genomic imprinting. n
C) consanguinity.
D) obligate carriers. - ANSWER -cn n n n
Joey, age 9, is admitted to a pediatric unit with Duchenne
n n n n n n n n n n
muscular dystrophy. He inherited this condition through a:
n n n n n n n
