6th EDITION HUETHER
M
M M
CHAPTER 1-42 TEST BANK
M M M
ChapterM01:MCellularMBiology
HuetherM&MMcCance:MUnderstandingMPathophysiology,M6thMEdition
MULTIPLEMCHOICE
1. AMstudentMisMobservingMaMcellMunderMtheMmicroscope.MItMisMobservedMtoMhaveMsu
percoiledMDNAwithMhistones.MWhichMofMtheMfollowingMwouldMalsoMbeMobservedM
byMtheMstudent?
a. AMsingleMcircularMchromosome
b. AMnucleus
c. Free-floatingMnuclearMmaterial
d. NoMorganelles
ANS:M B
TheMcellMdescribedMisMaMeukaryoticMcell,MsoMitMhasMhistonesMandMaMsupercoiledM
DNAMwithinMitsnucleus;Mthus,MtheMnucleusMshouldMbeMobserved.MAMsingleMcircul
arMchromosomeMcalledMaMprokaryoteMcontainsMfree-
floatingMnuclearMmaterialMbutMhasMnoMorganelles.
REF:M p.M2
2. AMnurseMisMinstructingMtheMstaffMaboutMcellularMfunctions.MWhichMcellularMfunctio
nMisMtheMnurseMdescribingMwhenManMisolatedMcellMabsorbsMoxygenMandMusesMitMtoMt
ransformMnutrientsMtoMenergy?
,a. MetabolicMabsorption
b. Communication
c. Secretion
d. Respiration
ANS:M D
TheMcell’sMabilityMtoMabsorbMoxygenMisMreferredMtoMasMrespirationMwhileMitsMcom
municationMabilityinvolvesMmaintenanceMofMaMsteadyMdynamicMstate,MmetabolicMa
bsorptionMprovidesMnutrition,MandMsecretionMallowsMforMtheMsynthesizingMofMnew
M substances.
REF:M p.M2
,3. AMeukaryoticMcellMisMundergoingMDNAMreplication.MInMwhichMregionMofMtheMcellMw
ouldMmostMoftheMgeneticMinformationMbeMcontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. NucleusMCytoplasm
ANS:M C
TheMregionMofMtheMcellMthatMcontainsMgeneticMmaterial,MincludingMaMlargeMamountMo
fMribonucleicacid,MmostMofMtheMDNA,MandMDNA-
bindingMproteins,MisMtheMnucleolus,MwhichMisMlocatedMwithintheMcell’sMnucleus.MMit
ochondriaMisMassociatedMwithMcellularMrespiration,MwhileMribosomesMareMinvolvedMw
ithMproteinMmanufacturing.MCytoplasmMisMaMfluidMfillingMthatMisMaMcomponentMofMthe
M cell.
REF:M p.M2
, 4. WhichMofMtheMfollowingMcanMremoveMproteinsMattachedMtoMtheMcell’sMbilaye
rMbyMdissolvingMthelayerMitself?
a. PeripheralMmembraneMproteins
b. IntegralMmembraneMproteins
c. Glycoproteins
d. CellMadhesionMmolecules
ANS:M B
ProteinsMdirectlyMattachedMtoMtheMmembraneMbilayerMcanMbeMremovedMbyMtheMactio
nMofMintegralmembraneMproteinsMthatMdissolveMtheMbilayer.MPeripheralMmembraneM
proteinsMresideMatMtheMsurfaceMwhileMcellMadhesionMmoleculesMareMonMtheMoutsideMof
M theMmembrane.MGlycoproteinMmarksMcellsMandMdoesMnotM float.
REF:M p.M7
5. WhichMofMtheMfollowingMcanMbindMtoMplasmaMmembraneMreceptors?
a. Oxygen
b. Ribosomes
c. AmphipathicMlipids
d. Ligands
ANS:M D
LigandsMareMtheMonlyMspecificMmoleculesMthatMcanMbindMwithMreceptorsMonMtheMcellMmem
brane.
REF:M p.M9
6. AMnurseMisMreviewingMaMreportMfromMaMpatientMwithMmetastaticMcancer.MWhatMa
lternationMinMtheextracellularMmatrixMwouldMsupportMtheMdiagnosisMofMmetasta
ticMcancer?
a. DecreasedMfibronectin
b. IncreasedMcollagen
c. DecreasedMelastin
d. IncreasedMglycoproteins
ANS:M A
OnlyMaMreducedMamountMofMfibronectinMisMfoundMinMsomeMtypesMofMcancerousMcells,Mallo
wingthemMtoMtravelMorMmetastasize.