IRON DEFIENCY ANAEMIT"Reduced Ab conc . in Blood below the lower limit
CAUSES :
-
> 1 .
Chronic Blood loss
normal range from /depletes adults)
in
(major
cause
of B
0 g/d
I
:
Iron
Recycling
-
NORMAL RANGE iron stores over time
9
:
aged
, RBC
:
provide
g/d
~ 11 5.
↓
Parameters majority of iron required for ANEMIA
assessing anemia : Hb
(major parameter erythropoiesis ↓
Red blood cell count
INTRODUCTION : But continous blood loss >
-
disrupt balance
anemia Herematocrit
-common
type of (pcr)
-
cause :
Insufficient t ?! Supplyea Heavy menstrual bleeding - CHRONIC BLOOD
↓
-
- > LOSS
> -
3. .
Ned demand GI
bleeding
Risk
Higher : - children
women
of childbearing age
·
patients lower socio-economic status
·
from
②
IRON DEFICIENCY
① FOUND :
plant
Y based
foods Amt iron lost
daily
forms) educed of img
-
:
(2
.
FOUND : Animal source
Transported loss
creat
Menstruating women It 0
5-img daily
-
= .
directly
absorbed -
-
> divalent metal
-
>
= CHypoxia- Inducible transporter IRON DISTRIBUTION :
Factor- 2)
80 % in He
·
·
(Iron Regulatory
Protein) stored
A
↓ 15-20% as
ferritin
·
home
oxygenase-1
-
& hemosiderin
Ferroprotein
(If Iron is not needed
A
immediately ⑦ FPN >
reducing iron
-
↑
converts export (when iron
level-high
Cliver hormone)
HIF-2
3 Regulation
-
h IRP
of
Transported
int a
delivers & carries Fest
Mepcidin From Absorption
CAUSES :
-
> 1 .
Chronic Blood loss
normal range from /depletes adults)
in
(major
cause
of B
0 g/d
I
:
Iron
Recycling
-
NORMAL RANGE iron stores over time
9
:
aged
, RBC
:
provide
g/d
~ 11 5.
↓
Parameters majority of iron required for ANEMIA
assessing anemia : Hb
(major parameter erythropoiesis ↓
Red blood cell count
INTRODUCTION : But continous blood loss >
-
disrupt balance
anemia Herematocrit
-common
type of (pcr)
-
cause :
Insufficient t ?! Supplyea Heavy menstrual bleeding - CHRONIC BLOOD
↓
-
- > LOSS
> -
3. .
Ned demand GI
bleeding
Risk
Higher : - children
women
of childbearing age
·
patients lower socio-economic status
·
from
②
IRON DEFICIENCY
① FOUND :
plant
Y based
foods Amt iron lost
daily
forms) educed of img
-
:
(2
.
FOUND : Animal source
Transported loss
creat
Menstruating women It 0
5-img daily
-
= .
directly
absorbed -
-
> divalent metal
-
>
= CHypoxia- Inducible transporter IRON DISTRIBUTION :
Factor- 2)
80 % in He
·
·
(Iron Regulatory
Protein) stored
A
↓ 15-20% as
ferritin
·
home
oxygenase-1
-
& hemosiderin
Ferroprotein
(If Iron is not needed
A
immediately ⑦ FPN >
reducing iron
-
↑
converts export (when iron
level-high
Cliver hormone)
HIF-2
3 Regulation
-
h IRP
of
Transported
int a
delivers & carries Fest
Mepcidin From Absorption
