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VanMeter and Hubert: Gould’s Pathophysiology for the Health Professions, 7th Edition
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MULTIPLE CHOICE v
1. Which of the following would be the most likely cause of an iatrogenic disease? a.
v v v v v v v v v v v v v v An
inherited disorder
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b. A combination of specific etiological factors
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c. An unwanted effect of a prescribed drug
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d. Prolonged exposure to toxic chemicals in the environment v v v v v v v
ANS: C v
2. The manifestations of a disease are best defined as the
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a. subjective feelings of discomfort during a chronic illness. v v v v v v v
b. signs and symptoms of a disease. v v v v v
c. factors that precipitate an acute episode of a chronic illness.
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d. early indicators of the prodromal stage of infection.
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ANS: B v
3. The best definition of the term prognosis is the
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a. precipitating factors causing an acute episode. v v v v v
b. number of remissions to be expected during the course of a chronic illness.
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c. predicted outcome or likelihood of recovery from a specific disease.
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d. exacerbations occurring during chronic illness. v v v v
ANS: C v
4. Which of the following is considered a systemic sign of disease?
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a. Swelling of the knee v v v
b. Fever
c. Pain in the neck v v v
d. Red rash on the face v v v v
ANS: B v
5. Etiology is defined as the study of the
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a. causes of a disease. v v v
b. course of a disease. v v v
c. expected complications of a disease. v v v v
d. manifestations of a disease. v v v
ANS: A v
6. A type of cellular adaptation in which there is a decrease in cell size is referred to as a.
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hypertrophy. v
b. metaplasia.
c. anaplasia.
d. atrophy.
, ANS: D v
7. A change in a tissue marked by cells that vary in size and shape and show increased
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mitotic figures would be called
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a. metaplasia.
b. atrophy.
c. dysplasia.
d. hypertrophy.
ANS: C v
8. A deficit of oxygen in the cells usually due to respiratory or circulatory problems is called a.
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apoptosis.
v
b. ischemia.
c. hypertrophy.
d. necrosis.
ANS: B v
9. When a group of cells in the body dies, the change is called
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a. ischemia.
b. gangrene.
c. hypoxia.
d. necrosis.
ANS: D v
10. Rigorous weightlifting/body building regimens may result in the skeletal muscle cells
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undergoing a. hypertrophy.
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b. dysplasia.
c. atrophy.
d. regeneration.
ANS: A v
11. The term cancer refers to
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a. dysplasia.
b. hyperplasia.
c. metaplasia.
d. malignant neoplasm. v
ANS: D v
12. To which of the following does the term apoptosis refer?
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a. Increased rate of mitosis by certain cells v v v v v v
b. Ischemic damage to cells v v v
, c. Liquefaction of necrotic tissue v v v
d. Preprogrammed cell self-destruction v v
ANS: D v
13. Which of the following statements is TRUE?
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a. Alteration of DNA does not change cell function. v v v v v v v
b. Damaged cells may be able to repair themselves. v v v v v v v
c. All types of cells die at the same rate.
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d. Mild ischemia causes immediate cell death.
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ANS: B v
14. Caseation necrosis refers to an area where
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a. cell proteins have been denatured.
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b. cells are liquefied by enzymes.
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c. dead cells form a thick cheesy substance.
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d. bacterial invasion has occurred. v v v
ANS: C v
15. Routine application of sun block to skin would be an example of
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a. an iatrogenic cause of cancer.
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b. a preventive measure.
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c. a precipitating factor.
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d. a predisposing condition.
v v
ANS: B v
16. A circumstance that causes a sudden acute episode of a chronic disease to occur is termed
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a. latent stage. v
b. predisposing factor. v
c. incidence.
d. precipitating factor. ANS: D v v v
17. The term homeostasis refers to
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a. the causative factors in a particular disease.
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b. maintenance of a stable internal environment. v v v v v
c. a condition that triggers an acute episode.
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d. a collection of signs and symptoms.
v v v v v
ANS: B v
18. Which term is used to describe a new and secondary or additional problem that arises after
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the original disease has been established?
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a. Symptoms
b. Occurrence
c. Manifestations
d. Complication
ANS: D v
19. Pathophysiology involves the study of v v v v