4/12/25, 8:10 NR547 Final Exam |
PM
NR547 FINAL EXAM QUESTIONS AND ANSWERS WITH COMPLETE
SOLUTIONS
Terms in this set (265)
SSRIs
SNRIs
Medications for depression SDRIs
TCAs
MAOIs
-Action: inhibit 5-HT reuptake
-Examples: citalopram, escitalopram, fluoxetine, paroxetine, sertraline
-Adverse effects:
• nausea
SSRIs • agitation
• diarrhea
• headache
• weight gain
• sexual side effects
-inhibit 5-HT reuptake
-inhibit NE reuptake (↑ energy, focus)
-increase DA in prefrontal cortex (↑ cognition)
-Examples: desvenlafaxine, duloxetine, levomilnacipran, venlafaxine
-Adverse effects:
• elevated blood pressure
• nausea
SNRIs
• sweating
• tremors
• anxiety
• insomnia
• constipation
• anorexia
• sexual dysfunction
-inhibit DA reuptake (↑alertness, motivation)
-inhibit NE reuptake (↑energy)
-Adverse effects:
• agitation
SDRIs
• headache
• dry mouth
• constipation
• weight loss
1/14
, 4/12/25, 8:10 NR547 Final Exam |
PM
-Action: inhibits the reuptake of serotonin and norepinephrine; blocks
norepinephrine, histamine, and acetylcholine receptors
-Examples: amitriptyline, clomipramine, desipramine, doxepin
-Common Side Effects:
• dry mouth
• constipation
TCAs • blurred vision
• urinary retention
• sedation
• weight gain
• hypotension
• tachycardia
• sexual dysfunction
-Action: increases norepinephrine and serotonin by inhibiting the enzyme that
inactivates it
-Examples: isocarboxazid, phenelzine, tranylcypromine
-Common Side Effects:
MAOIs
• sedation
• dizziness
• sexual dysfunction
• hypertensive crisis
Prescribing pearls: citalopram (Celexa) mild antihistamine effects
Prescribing pearls: escitalopram no known drug interactions
(Lexapro)
Prescribing pearls: fluoxetine (Prozac) longest half-life
Prescribing pearls: paroxetine (Paxil) also treats social anxiety and insomnia
Prescribing pearls: fluvoxamine (Luvox) treats anxious depression smokers require increased dose
Prescribing pearls: sertraline (Zoloft) also treats social anxiety and hypersomnolence
Prescribing pearls: bupropion NDRI may improve energy, alertness, and motivation; not first line treatment for
(Wellbutrin) anxiety; contraindicated in clients with a history of seizures
effective for atypical pain at higher doses; appropriate for clients who present
Prescribing pearls: duloxetine (Cymbalta) with somatic symptoms of depression; effective for atypical pain, such as
fibromyalgia and diabetic neuropathy
treats both depression and anxiety disorders, ensure trial of higher dose before
Prescribing pearls: venlafaxine (Effexor)
switching to a different medication
Prescribing pearls: desvenlafaxine effective for perimenopausal vasomotor symptoms
(Pristiq)
-Client preference
-Prior treatment response
-Anticipated adverse effects
considered when selecting a medication:
-Comorbidities
-Half-life and interactions
-Cost
-Increase dose gradually
-Switch to a different drug within the same class
if a medication is not achieving efficacy:
-Switch to drug in a different class
-Add a second medication
Use to protect against suicide lithium
MDD and BPD genetics genetic factors contribute 31-42% of the disease risk in MDD and 59-85% in BPD
2/14
PM
NR547 FINAL EXAM QUESTIONS AND ANSWERS WITH COMPLETE
SOLUTIONS
Terms in this set (265)
SSRIs
SNRIs
Medications for depression SDRIs
TCAs
MAOIs
-Action: inhibit 5-HT reuptake
-Examples: citalopram, escitalopram, fluoxetine, paroxetine, sertraline
-Adverse effects:
• nausea
SSRIs • agitation
• diarrhea
• headache
• weight gain
• sexual side effects
-inhibit 5-HT reuptake
-inhibit NE reuptake (↑ energy, focus)
-increase DA in prefrontal cortex (↑ cognition)
-Examples: desvenlafaxine, duloxetine, levomilnacipran, venlafaxine
-Adverse effects:
• elevated blood pressure
• nausea
SNRIs
• sweating
• tremors
• anxiety
• insomnia
• constipation
• anorexia
• sexual dysfunction
-inhibit DA reuptake (↑alertness, motivation)
-inhibit NE reuptake (↑energy)
-Adverse effects:
• agitation
SDRIs
• headache
• dry mouth
• constipation
• weight loss
1/14
, 4/12/25, 8:10 NR547 Final Exam |
PM
-Action: inhibits the reuptake of serotonin and norepinephrine; blocks
norepinephrine, histamine, and acetylcholine receptors
-Examples: amitriptyline, clomipramine, desipramine, doxepin
-Common Side Effects:
• dry mouth
• constipation
TCAs • blurred vision
• urinary retention
• sedation
• weight gain
• hypotension
• tachycardia
• sexual dysfunction
-Action: increases norepinephrine and serotonin by inhibiting the enzyme that
inactivates it
-Examples: isocarboxazid, phenelzine, tranylcypromine
-Common Side Effects:
MAOIs
• sedation
• dizziness
• sexual dysfunction
• hypertensive crisis
Prescribing pearls: citalopram (Celexa) mild antihistamine effects
Prescribing pearls: escitalopram no known drug interactions
(Lexapro)
Prescribing pearls: fluoxetine (Prozac) longest half-life
Prescribing pearls: paroxetine (Paxil) also treats social anxiety and insomnia
Prescribing pearls: fluvoxamine (Luvox) treats anxious depression smokers require increased dose
Prescribing pearls: sertraline (Zoloft) also treats social anxiety and hypersomnolence
Prescribing pearls: bupropion NDRI may improve energy, alertness, and motivation; not first line treatment for
(Wellbutrin) anxiety; contraindicated in clients with a history of seizures
effective for atypical pain at higher doses; appropriate for clients who present
Prescribing pearls: duloxetine (Cymbalta) with somatic symptoms of depression; effective for atypical pain, such as
fibromyalgia and diabetic neuropathy
treats both depression and anxiety disorders, ensure trial of higher dose before
Prescribing pearls: venlafaxine (Effexor)
switching to a different medication
Prescribing pearls: desvenlafaxine effective for perimenopausal vasomotor symptoms
(Pristiq)
-Client preference
-Prior treatment response
-Anticipated adverse effects
considered when selecting a medication:
-Comorbidities
-Half-life and interactions
-Cost
-Increase dose gradually
-Switch to a different drug within the same class
if a medication is not achieving efficacy:
-Switch to drug in a different class
-Add a second medication
Use to protect against suicide lithium
MDD and BPD genetics genetic factors contribute 31-42% of the disease risk in MDD and 59-85% in BPD
2/14
