K K K K K K K K
Edition Frandsen Test Bank
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,Abrams' Clinical Drug Therapy: Rationales for Nursing Practice 12th EditionF
K K K K K K K K K K
randsen Test Bank
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ChapterK 1K TheKFoundationK ofK Pharmacology:K QualityKandK Safety
AKwomanKhasKbeenKprescribedKparoxetineKhy
drochloride,KwhichKisKanKantidepressantKagen
tKadministeredKinKpillKform.KTheKmedicationK i
1.
sK administeredK forK herK obsessive-
compulsiveKdisorder.KThisKmedicationKwil
lKproduceK whichK ofKtheK followingKeffects?
A) Curative
B) Systemic
C) Local
D) Parenteral
Ans: B
Feedback:
DrugsKthatK produceK systemicKeffectsKareK taken
KintoKtheKbody,KcirculatedKthroughKtheKbloodstr
eamKtoKtheirK sitesKofKactionK inKvariousKbodyKti
ssues,K andK eventuallyKeliminatedK fromKtheKbo
dy.KCurativeKagentsKareKgivenKtoKcureKaKdiseas
eKprocess.KInKthisKcase,KparoxetineKhydrochlori
deK willKcontrolKtheK symptomsKbutKnotKcureKth
eKdisorder.KDrugsKwithKlocalKeffects,KsuchKasKs
unscreenKandKlocalKanesthetics,KactKmainlyKatKt
heKsiteKofKapplication.KParoxetineKhydrochlori
deKisK notK administeredKparenterally.K Parenter
alK agentsK areKadministeredK subcutaneously,K in
tramuscularly,KorKintravenously.
AKpatientK hasKbeenKprescribedKanKantibiotic.K
ThisKmedicationK isKaKnaturallyKoccurringKsub
2. stanceK thatK hasK beenK chemicallyKmodified.
WhatKisKanotherKnameKforKthisKtypeK
ofKmedication?
A) SyntheticK drug
B) SemisyntheticK drug
C) BiotechnologyK drug
D) PrototypeK drug
Ans: B
Feedback:
, SemisyntheticK drugsK(e.g.,KmanyKantibiotics)Ka
reKnaturallyKoccurringKsubstancesKthatKhaveKbe
enK chemicallyK modified.K SyntheticK drugsK areK
moreKstandardizedKinKtheirKchemicalKcharacteri
stics,KmoreKconsistentK inK theirKeffects,KandKles
sKlikelyKtoKproduceKallergicKreactions.KBiotech
nologyKdrugsKinvolveKmanipulatingK DNAKand
K RNAKandKrecombiningK genesK intoK hybridK m
oleculesK thatKcanKbeKinsertedKintoKlivingKorgan
isms.
PrototypeKdrugsKareKtheKfirstKdrugKofK
aKparticularK groupK toK beK developed.
AKpatientK isK administeredK morphine.K Morphin
eKisKaKprototypicalK drugKthatKcanKbeKclassifiedK
3.
in
differentKways.KWhichKofKtheKfollowin
gKclassificationsK appliesK toK morphine?
A) CentralK nervousK systemK depressant
B) CentralK nervousK systemK stimulant
C) Anti-inflammatory
D) Antihypertensive
Ans: A
Feedback:
DrugsKareKclassifiedKaccordingKtoKtheirKeffects
KonK particularK bodyK systems,K theirK therapeuticK
uses,KandKtheirKchemicalKcharacteristics.K ForKe
xample,KmorphineKcanKbeKclassifiedKasKaKcentr
alKnervousKsystemKdepressantKandKaKnarcoticK o
rK opioidK analgesic.KAKcentralK nervousKsystemKs
timulantK increasesK attentionK andKraisesKmood
.KAnKanti-
inflammatoryKagentKdecreasesKinflammationKat
K theK siteK ofKtissueK orKjointK inflammation.KAnK a
ntihypertensiveK agentKreducesK bloodK pressure.
AKpatientKisKadministeredKamoxicillinK(Amox
il).KTheKgenericKnameKofKthis
4.
medicationK indicatesK thatK itK belongsK toK whic
hKdrugK group?
A) SelectiveK serotoninK reuptakeK inhibitors
B) Diuretics
C) Penicillins
D) ACEK inhibitors
Ans: C
, Feedback:
TheKgenericKnameKoftenKindicatesKtheKdrugKgr
oupK (e.g.,K drugsK withK genericK namesK endingKi
nK ―cillin‖K areK penicillins).K SelectiveK serotonin
KreuptakeK inhibitorsK areK medicationsK thatK hav
eKantidepressantKeffects;KSSRIKisKaKbroadKclas
sification,KnotKaK genericKname.KDiureticsKareK
medicationsKthatK increaseKurineKoutput;Kdiuret
icKisKaKbroadKclassification,K notKaK genericKnam
e.KACEK inhibitorK isKtheK broadKclassificationK f
orK theK angiotensin-
convertingKenzymeK inhibitors,K notK theK generi
cK name.
TheKadministrationKofKdiphenhydramineK(Ben
adryl),KwhichKisKanKover-the-counter
5.
medication,K isK regulatedK byK whichK governmen
tKagency?
A) PublicKHealthKService
B) FederalKTradeK Commission
OccupationalK SafetyKandKHealth
C)
Administration
D) FoodK andKDrugKAdministration
Ans: D
Feedback:
TheK FoodK andK DrugKAdministrationK approve
sKdrugsKforKover-the-
counterKavailability,KincludingKtheKtransferKof
KdrugsK fromKprescriptionK toK OTCK status,K and
K mayK requireKclinicalK trialsK toK determineK theK
safetyKandKeffectivenessKofKOTCKuse.KTheK P
ublicKHealthKServiceKisKregulatedK byKtheKstate
K toK maintainKtheK healthK ofK individualK citizens
K ofK theK state.KTheK FederalKTradeK Commissio
nKregulatesKimportsK andKexportsKthroughoutK t
heK nation.
TheK OccupationalK SafetyKandKHealthKAd
ministrationK regulatesK safetyKwithinK theKw
orkplace.
TheKadministrationK ofKanabolicK steroidsK is
6.
KregulatedK byK whichK ofK theK followingK law
s?
A) TheK Food,KDrug,KandK CosmeticKActKofK1938
TheK ComprehensiveK DrugKAbuseK Preventio
B)
nKandK ControlKAct
C) TheKHarrisonKNarcoticKAct