TEST BANK FOR v v
Evolutionary Analysis 5th Edition by Herron Jon; Freeman Scott ISBN 9780321998378
v v v v v v v v v v
Chapter 1-20
v v
Chapter 1 v v v A Case for Evolutionary Thinking: Understanding HIV
v v v v v v
1) In which of the following regions has AIDS killed the largest number of individuals?
v v v v v v v v v v v v v
A) India
B) Sub-Saharan Africa v
C) United States v
D) China
E) United Kingdom v
Answer: B
v v
vSection: 1.1 v
Skill: Knowledge/Comprehension
v
2) The HIV virus contains all of the following components except
v v v v v v v v v v .
A) integrase
B) double-stranded RNA v
C) single-stranded RNA v
D) reverse transcriptase v
E) protease
Answer: B
v v
Section:
v
v1.1
Skill: Knowledge/Comprehension
v
3) The acronym HIV stands for which of the following?
v v v v v v v v
A) human intercellular virus v v
B) human immune virus v v
C) human immunodeficiency virus v v
D) human immunity virus v v
E) human immunodeficiency vector
v v
Answer: C
v v
Section: 1.1 v
Skill: Knowledge/Comprehension
v
4) Which of the following enzymes is responsible for transcribing viral RNA into DNA?
v v v v v v v v v v v v
A) RNA polymerase v
B) reverse transcriptase v
C) DNA polymerase
v
D) reverse integrase v
E) RNA duplicasev
Answer: B
v v
Section: 1.1
v v
Skill: Knowledge/Comprehension
v
1
Copyright © 2014 Pearson Education, Inc.
v v v v v
,5) The proteins that enable the HIV virus to bind to cells are typically CD4 and CCR5. On what
v v v v v v v v v v v v v v v v v
type of cells are these proteins typically observed?
v v v v v v v v
A) plasma cells v
B) dendritic cells v
C) effector helper T cells v v v
D) memory helper T cells v v v
E) both C and D v v v
Answer: E
v v
Section: 1.1
v v
Skill: Knowledge/Comprehension
v
6) The AIDS phase of HIV infection begins when the concentration of CD4 T cells in the blood
v v v v v v v v v v v v v v v v
drops below what concentration?
v v v v
A) 2,000 cells per cubic millimeter
v v v v
B) 1,000 cells per cubic millimeter
v v v v
C) 500 cells per cubic millimeter
v v v v
D) 200 cells per cubic millimeter
v v v v
E) No CD4 T cells are observed.
v v v v v
Answer: D
v v
Section: 1.1 v
Skill: Knowledge/Comprehension
v
7) Which of the following drug categories are used to treat HIV infections?
v v v v v v v v v v v
A) integrase inhibitors v
B) protease inhibitors v
C) reverse transcriptase inhibitors v v
D) DNAse inhibitors v
E) fusion inhibitors v
Answer: D
v v
Section: 1.2
v v
Skill: Knowledge/Comprehension
v
8) Coreceptor inhibitors block HIV infection by preventing which of the following?
v v v v v v v v v v
A) binding of the HIV virion onto the plasma membrane
v v v v v v v v
B) binding of the HIV virion onto the CCR5 receptor
v v v v v v v v
C) binding of the HIV virion onto the gp120 protein
v v v v v v v v
D) degrading the coreceptor so the virion cannot attach v v v v v v v
E) binding of the HIV virion onto the CD4 receptor
v v v v v v v v
Answer: B
v v
Section: 1.2 v
Skill: Application/Analysis
v
9) What is the effect of the ∆32 allele of CCR5 on HIV binding?
v v v v v v v v v v v v
A) appears on the surface of CD4 T cells, but the HIV virion is unable to infect the host cell
v v v v v v v v v v v v v v v v v v
B) does not appear on the surface of CD4 T cells
v v v v v v v v v
C) appears on the surface of the CD4 T cells and inactivates the virion upon binding
v v v v v v v v v v v v v v
D) interferes with binding of the virion to the CD4 receptor protein
v v v v v v v v v v
2
Copyright © 2014 Pearson Education, Inc. v v v v v
,E) appears on the surface of the CD4 T cells and causes the virion to lyse upon binding
v v v v v v v v v v v v v v v v
Answer: B
v v
Section: 1.3 v
Skill: Application/Analysis
v
10) The ∆32 allele of CCR5 is found at the highest frequency in which of the following
v v v v v v v v v v v v v v v
populations?
v
A) Africans
B) Japanese
C) North Americans v
D) Europeans
E) South Americans v
Answer: D
v v
vSection: 1.3 v
Skill: Knowledge/Comprehension
v
11) HIV-1 is believed to have been transmitted to humans from which of the following
v v v v v v v v v v v v v
organisms?
v
A) gorillas
B) sooty mangabeys v
C) African green monkeys v v
D) chimpanzees
E) baboons
Answer: D
v v
Section:
v
v1.4
Skill: Knowledge/Comprehension
v
12) HIV-1 Group M is responsible for 95% of human infections. When is it estimated that HIV-1
v v v v v v v v v v v v v v v
Group M was transferred to humans?
v v v v v v
A) 1980
B) 1960
C) 1930
D) 1995
E) 1900
Answer: C v
Section:
v
v1.4
Skill: Knowledge/Comprehension
v
13) Antibodies and killer T cells recognize HIV or HIV-infected cells by binding to short pieces
v v v v v v v v v v v v v v
of viral proteins displayed on the virus or the infected host cell. These short pieces of viral
v v v v v v v v v v v v v v v v v
proteins are called
v v . v v
A) coat proteinsv
B) virosomes
C) proteosomes
D) epitopes
3
Copyright © 2014 Pearson Education, Inc.
v v v v v
, E) episomes
Answer: D
v v
4
Copyright © 2014 Pearson Education, Inc.
v v v v v
Evolutionary Analysis 5th Edition by Herron Jon; Freeman Scott ISBN 9780321998378
v v v v v v v v v v
Chapter 1-20
v v
Chapter 1 v v v A Case for Evolutionary Thinking: Understanding HIV
v v v v v v
1) In which of the following regions has AIDS killed the largest number of individuals?
v v v v v v v v v v v v v
A) India
B) Sub-Saharan Africa v
C) United States v
D) China
E) United Kingdom v
Answer: B
v v
vSection: 1.1 v
Skill: Knowledge/Comprehension
v
2) The HIV virus contains all of the following components except
v v v v v v v v v v .
A) integrase
B) double-stranded RNA v
C) single-stranded RNA v
D) reverse transcriptase v
E) protease
Answer: B
v v
Section:
v
v1.1
Skill: Knowledge/Comprehension
v
3) The acronym HIV stands for which of the following?
v v v v v v v v
A) human intercellular virus v v
B) human immune virus v v
C) human immunodeficiency virus v v
D) human immunity virus v v
E) human immunodeficiency vector
v v
Answer: C
v v
Section: 1.1 v
Skill: Knowledge/Comprehension
v
4) Which of the following enzymes is responsible for transcribing viral RNA into DNA?
v v v v v v v v v v v v
A) RNA polymerase v
B) reverse transcriptase v
C) DNA polymerase
v
D) reverse integrase v
E) RNA duplicasev
Answer: B
v v
Section: 1.1
v v
Skill: Knowledge/Comprehension
v
1
Copyright © 2014 Pearson Education, Inc.
v v v v v
,5) The proteins that enable the HIV virus to bind to cells are typically CD4 and CCR5. On what
v v v v v v v v v v v v v v v v v
type of cells are these proteins typically observed?
v v v v v v v v
A) plasma cells v
B) dendritic cells v
C) effector helper T cells v v v
D) memory helper T cells v v v
E) both C and D v v v
Answer: E
v v
Section: 1.1
v v
Skill: Knowledge/Comprehension
v
6) The AIDS phase of HIV infection begins when the concentration of CD4 T cells in the blood
v v v v v v v v v v v v v v v v
drops below what concentration?
v v v v
A) 2,000 cells per cubic millimeter
v v v v
B) 1,000 cells per cubic millimeter
v v v v
C) 500 cells per cubic millimeter
v v v v
D) 200 cells per cubic millimeter
v v v v
E) No CD4 T cells are observed.
v v v v v
Answer: D
v v
Section: 1.1 v
Skill: Knowledge/Comprehension
v
7) Which of the following drug categories are used to treat HIV infections?
v v v v v v v v v v v
A) integrase inhibitors v
B) protease inhibitors v
C) reverse transcriptase inhibitors v v
D) DNAse inhibitors v
E) fusion inhibitors v
Answer: D
v v
Section: 1.2
v v
Skill: Knowledge/Comprehension
v
8) Coreceptor inhibitors block HIV infection by preventing which of the following?
v v v v v v v v v v
A) binding of the HIV virion onto the plasma membrane
v v v v v v v v
B) binding of the HIV virion onto the CCR5 receptor
v v v v v v v v
C) binding of the HIV virion onto the gp120 protein
v v v v v v v v
D) degrading the coreceptor so the virion cannot attach v v v v v v v
E) binding of the HIV virion onto the CD4 receptor
v v v v v v v v
Answer: B
v v
Section: 1.2 v
Skill: Application/Analysis
v
9) What is the effect of the ∆32 allele of CCR5 on HIV binding?
v v v v v v v v v v v v
A) appears on the surface of CD4 T cells, but the HIV virion is unable to infect the host cell
v v v v v v v v v v v v v v v v v v
B) does not appear on the surface of CD4 T cells
v v v v v v v v v
C) appears on the surface of the CD4 T cells and inactivates the virion upon binding
v v v v v v v v v v v v v v
D) interferes with binding of the virion to the CD4 receptor protein
v v v v v v v v v v
2
Copyright © 2014 Pearson Education, Inc. v v v v v
,E) appears on the surface of the CD4 T cells and causes the virion to lyse upon binding
v v v v v v v v v v v v v v v v
Answer: B
v v
Section: 1.3 v
Skill: Application/Analysis
v
10) The ∆32 allele of CCR5 is found at the highest frequency in which of the following
v v v v v v v v v v v v v v v
populations?
v
A) Africans
B) Japanese
C) North Americans v
D) Europeans
E) South Americans v
Answer: D
v v
vSection: 1.3 v
Skill: Knowledge/Comprehension
v
11) HIV-1 is believed to have been transmitted to humans from which of the following
v v v v v v v v v v v v v
organisms?
v
A) gorillas
B) sooty mangabeys v
C) African green monkeys v v
D) chimpanzees
E) baboons
Answer: D
v v
Section:
v
v1.4
Skill: Knowledge/Comprehension
v
12) HIV-1 Group M is responsible for 95% of human infections. When is it estimated that HIV-1
v v v v v v v v v v v v v v v
Group M was transferred to humans?
v v v v v v
A) 1980
B) 1960
C) 1930
D) 1995
E) 1900
Answer: C v
Section:
v
v1.4
Skill: Knowledge/Comprehension
v
13) Antibodies and killer T cells recognize HIV or HIV-infected cells by binding to short pieces
v v v v v v v v v v v v v v
of viral proteins displayed on the virus or the infected host cell. These short pieces of viral
v v v v v v v v v v v v v v v v v
proteins are called
v v . v v
A) coat proteinsv
B) virosomes
C) proteosomes
D) epitopes
3
Copyright © 2014 Pearson Education, Inc.
v v v v v
, E) episomes
Answer: D
v v
4
Copyright © 2014 Pearson Education, Inc.
v v v v v
