NGR6200 Hyperlipidemia Review Exam
Questions And Answers |Latest 2025 |
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1. What are the 4 high risk groups identified in the ACC/AHA Guidelines on the Treatment of
Blood Cholesterol to Reduce ASCVD in Adults that should be treated with statins? - Answer✔1.
Individuals with clinical ASCVD including: ACS, MI, angina, revascularization, stroke, TIA, and
PVD
2. LDL > 190 mg/dL
3. DM age 40-75 with LDL > 70 mg/dL
4. Individuals age 40-75 with risk of CV disease >7.5% using the Pooled Cohort Calculation
2. The variables in the Pooled Cohort Equation include age, race, total and HDL-cholesterol,
systolic BP (including treated or untreated status), diabetes, and current smoking status. This
calculation measures the _______ year risk of developing ASCVD and is thought to more
accurate than the Framingham Risk Assessment. - Answer✔10 year risk
3. Individuals with an LDL >190 mg/dL are most likely to have a genetic defect in the LDL
receptors called_________? - Answer✔Familial hypercholesterolemia (FH)
4. Statins are recommended for children with LDL > 190 mg/dL starting at age _______ years in
patients with heterozygous FH. - Answer✔10 years
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5. Which of the 4 high risk groups have the recommendation of treatment with high intensity
statins according to the AAC/AHA Guidelines? - Answer✔Individuals with ASCVD and LDL > 190
mg/dL
6. Which of the statins are considered "high intensity" statins to lower LDL > 50%?" - Answer✔-
Atorvastatin 40-80 mg
- Rosuvastatin 20-40 mg
7. Which of the 4 groups have the recommendation of treatment with moderate intensity
statins to lower LDL >30-50%? - Answer✔1. Patients with DM
2. Patients with a risk of ASCVD of 7.5% or greater using the Pooled Cohort equation
8. Which statins are considered "moderate intensive statins" to lower LDL 30-50%? - Answer✔-
Atorvastatin 10-20 mg
- Pravastatin 40 mg
- Rosuvastatin 10 mg
- Lovastatin 40 mg
- Simvastatin 20-40 mg
9. According to the ACC/AHA Guidelines, is it necessary to titrate by starting with lower doses of
statins? - Answer✔No
- because this may lead to under treatment, however it may be necessary in patients that can't
tolerate the higher doses of statins
10. According to the ACC/AHA Guidelines are non statins routinely recommended? -
Answer✔No
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- because non statin drugs have failed to show a decrease in cardiovascular risks
11. Some individuals may not fall into any of the 4 high risk groups but may still need to be
treated. Other factors to consider in making the decision are: - Answer✔1. Patient preference
2. LDL-C ≥160 mg/dL or other evidence of genetic
hyperlipidemias
3. Family history of premature ASCVD with onset
<55 years of age in a first degree male relative
or <65 years of age in a first degree female
relative
4. High-sensitivity C-reactive protein >2 mg/L
5. CAC score ≥300 Agatston units ≥75 percentile
for age, sex, and ethnicity
6. Ankle-brachial index <0.9
7. Elevated lifetime risk of ASCVD
12. What is the definition of a family history of premature ASCVD? - Answer✔<55 years of age
in a first degree male relative
or
< 65 years of age in a first degree female relative
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