1z|zPzazgzez|z©zcopyrightz 2024/2025z|zGradezA+
NR 507: Advanced Pathophysiology Midter
z z z z
m Questions andCorrect Answers |
z z z z z
Latest Update z
Asthma
✓ ~~>Chroniczdiseasezdueztozbronchoconstrictionzandzanzexcessivezin
flammatoryzresponsezinzthezbronchioles
Whatzarez5zs/szofzasthma
✓ ~~>coughingz
wheezing
shortnesszofzbreathz
rapidzbreathingzch
estztightness
Pathophysiologyzofzasthmaz(5)
✓ ~~>-airwayzinflammation,zbronchialzhyper-
reactivityzandzsmoothzmusclezspasm
-excesszmucuszproductionzandzaccumulation
-hypertrophyzofzbronchialzsmoothzmuscle
-airflowzobstruction
Master01 | z z September,z2024/2025 |zLatestzupdate
, 2z|zPzazgzez|z©zcopyrightz 2024/2025z|zGradezA+
-decreasedzalveolarzventilation
Bronchioles
✓ ~~>smallerzpassagewayszthatzoriginatezfromzthezbronchizthatzbecomezth
ezalveoli
3zlayerszofzthezbronchioles
✓ ~~>innermostzlayerzm
iddlezlayerz-zlaminazpropria
outermostz layer
laminazpropria
✓ ~~>thezmiddlezlayerzofzthezbronchioles
structurezofzthezlaminazpropria
✓ ~~>embeddedzwithzconnectiveztissuezcellszandzimmunezcells
purposezofzthezlaminazpropria
✓ ~~>whitezbloodzcellszarezpresentztozhelpzprotectzthezairways
Master01 | z z September,z2024/2025 |zLatestzupdate
, 3z|zPzazgzez|z©zcopyrightz 2024/2025z|zGradezA+
Howzdoeszthezlaminazpropriazeffectzthezlungszinzregardsztozasthma
✓ ~~>thezWBCszprotectivezfeaturezgoeszintozoverdrivezcausingzanzin
flammatoryzresponsezthatzdamageszhostztissue
Whatzdoeszthezinnermostzlayerzofzthezbronchioleszcontain
✓ ~~>columnarzepithelialzellszandzmucuszproducingzgobletzcells
Whatzdoeszthezoutermostzlayerzofzthezbronchioleszcontain
✓ ~~>smoothzmusclezcells
whatzdoeszthezoutermostzlayerzofzthezbronchioleszdo
✓ ~~>controlz thez airwaysz abilityz tozconstrictzandz dilate
alveolarzhyperinflation
✓ ~~>Whenzairziszunableztozmovezoutzofzthezalveolarzlikezitzshouldzdueztozbro
nchialzwallszcollapsingzaroundzpossiblezmucuszplugzthusztrappingzairzinsid
e
howzdoeszhyperinflationzoccur?
Master01 | z z September,z2024/2025 |zLatestzupdate
, 4z|zPzazgzez|z©zcopyrightz 2024/2025z|zGradezA+
✓ ~~>thezongoingzinflammatoryzprocesszofzasthmazproduceszmucuszandzp
uszplugzthatzthezbronchialzwallszcollapsezaround
Effectzofzhyperinflationzofzthezalveolar
✓ ~~>-expandedzthoraxzandzhypercapniaz(retentionzofzCO2)
- respiratoryzacidosis
Whatzareztwozanticholinergiczdrugszusedzforzasthma
✓ ~~>tiotropiumzandzipratropium
Whatzdozanticholinergicszdozinzthezlungs?
✓ ~~>Thesezdrugszblockzthezeffectszofzthezparasympatheticznervouszs
ystem
- increasingzbronchodilation
MOAzofzanticholinergiczdrugszforzasthma
✓ ~~>thezparasympatheticzsystemziszstimulatedzbyzthezvagalznerveztozre
leasezacetylcholinezwhichzbindsztozthezcholinergiczreceptorszofzthezresp
iratoryztractztozcausezbronchialzconstrictionz=zdecreasedzairflow
Master01 | z z September,z2024/2025 |zLatestzupdate
NR 507: Advanced Pathophysiology Midter
z z z z
m Questions andCorrect Answers |
z z z z z
Latest Update z
Asthma
✓ ~~>Chroniczdiseasezdueztozbronchoconstrictionzandzanzexcessivezin
flammatoryzresponsezinzthezbronchioles
Whatzarez5zs/szofzasthma
✓ ~~>coughingz
wheezing
shortnesszofzbreathz
rapidzbreathingzch
estztightness
Pathophysiologyzofzasthmaz(5)
✓ ~~>-airwayzinflammation,zbronchialzhyper-
reactivityzandzsmoothzmusclezspasm
-excesszmucuszproductionzandzaccumulation
-hypertrophyzofzbronchialzsmoothzmuscle
-airflowzobstruction
Master01 | z z September,z2024/2025 |zLatestzupdate
, 2z|zPzazgzez|z©zcopyrightz 2024/2025z|zGradezA+
-decreasedzalveolarzventilation
Bronchioles
✓ ~~>smallerzpassagewayszthatzoriginatezfromzthezbronchizthatzbecomezth
ezalveoli
3zlayerszofzthezbronchioles
✓ ~~>innermostzlayerzm
iddlezlayerz-zlaminazpropria
outermostz layer
laminazpropria
✓ ~~>thezmiddlezlayerzofzthezbronchioles
structurezofzthezlaminazpropria
✓ ~~>embeddedzwithzconnectiveztissuezcellszandzimmunezcells
purposezofzthezlaminazpropria
✓ ~~>whitezbloodzcellszarezpresentztozhelpzprotectzthezairways
Master01 | z z September,z2024/2025 |zLatestzupdate
, 3z|zPzazgzez|z©zcopyrightz 2024/2025z|zGradezA+
Howzdoeszthezlaminazpropriazeffectzthezlungszinzregardsztozasthma
✓ ~~>thezWBCszprotectivezfeaturezgoeszintozoverdrivezcausingzanzin
flammatoryzresponsezthatzdamageszhostztissue
Whatzdoeszthezinnermostzlayerzofzthezbronchioleszcontain
✓ ~~>columnarzepithelialzellszandzmucuszproducingzgobletzcells
Whatzdoeszthezoutermostzlayerzofzthezbronchioleszcontain
✓ ~~>smoothzmusclezcells
whatzdoeszthezoutermostzlayerzofzthezbronchioleszdo
✓ ~~>controlz thez airwaysz abilityz tozconstrictzandz dilate
alveolarzhyperinflation
✓ ~~>Whenzairziszunableztozmovezoutzofzthezalveolarzlikezitzshouldzdueztozbro
nchialzwallszcollapsingzaroundzpossiblezmucuszplugzthusztrappingzairzinsid
e
howzdoeszhyperinflationzoccur?
Master01 | z z September,z2024/2025 |zLatestzupdate
, 4z|zPzazgzez|z©zcopyrightz 2024/2025z|zGradezA+
✓ ~~>thezongoingzinflammatoryzprocesszofzasthmazproduceszmucuszandzp
uszplugzthatzthezbronchialzwallszcollapsezaround
Effectzofzhyperinflationzofzthezalveolar
✓ ~~>-expandedzthoraxzandzhypercapniaz(retentionzofzCO2)
- respiratoryzacidosis
Whatzareztwozanticholinergiczdrugszusedzforzasthma
✓ ~~>tiotropiumzandzipratropium
Whatzdozanticholinergicszdozinzthezlungs?
✓ ~~>Thesezdrugszblockzthezeffectszofzthezparasympatheticznervouszs
ystem
- increasingzbronchodilation
MOAzofzanticholinergiczdrugszforzasthma
✓ ~~>thezparasympatheticzsystemziszstimulatedzbyzthezvagalznerveztozre
leasezacetylcholinezwhichzbindsztozthezcholinergiczreceptorszofzthezresp
iratoryztractztozcausezbronchialzconstrictionz=zdecreasedzairflow
Master01 | z z September,z2024/2025 |zLatestzupdate
