1 of 125
Term
Which of the following metabolic shifts would reduce the activity of
the glycolytic pathway?
Give this one a try later!
, insulin: used to store excess dietary fuels such that they can be used in the fasted
state [anabolic: building, builds molecules or stores resources (vs. catabolic,
referring to breaking down of molecules/dismantling stores)]
Hepatic glycogenolysis and gluconeogenesis are the two pathways that release
glucose into the blood stream in the fasted state. Muscle glycogenolysis does not
contribute to this pool of glucose.
Generation of glucose 1-phosphate to be used for glycogen synthesis
increased ATP; high levels of ATP are highly regulatory of metabolic pathways
(suggests that we don't need to oxidize any more fuel products, we should be
storing them instead --> reduces activity)
Don't know?
2 of 125
Term
Which of the following best describes the structure of heme?
Give this one a try later!
A planar porphyrin ring that A helical structure that binds
binds iron magnesium
A spherical protein that binds oxygen
, A linear chain of amino acids that
binds copper
Don't know?
3 of 125
Definition
transketolase; Transketolase requires the cofactor thiamine
diphosphate and activity of the enzyme can be used as to determine
nutritional status.
Give this one a try later!
A farmer finds a cow dead in his field and notices an unusual plant nearby. Autopsy
results show an elevated level of citrate present in the cow's mitochondria. This data
collectively suggest inhibition of which of the following enzymes?
Alanine can be shuttled from the skeletal muscle to the liver where it is deaminated
to generate pyruvate. When glucagon is high, pyruvate is primarily used as a
substrate for which of the following pathways?
A patient presents to the emergency department with lactic acidosis. A
deficiency in thiamine (TPP) is suspected and this will be consistent with a
decrease in the activity of following enzymes?
A deficiency in thiamine can reduce the activity of the pyruvate dehydrogenase
complex. Under these conditions, you would expect to have a higher than normal
, blood concentration of which of the following metabolites?
Don't know?
4 of 125
Term
In the image below the blue line indicates enzyme kinetics with no
inhibitor present. Based on this information which of the following is
true?
Give this one a try later!
the enzyme will require a lower
green line shows enzyme kinetics
substrate concentration to reach 1/2
with no substrate present
vmax
green line shows enzyme
green line represents enzyme kinetics
kinetics with the addition of a
with a substrate analog
noncompetitive inhibitor
Don't know?
5 of 125
Term
Term
Which of the following metabolic shifts would reduce the activity of
the glycolytic pathway?
Give this one a try later!
, insulin: used to store excess dietary fuels such that they can be used in the fasted
state [anabolic: building, builds molecules or stores resources (vs. catabolic,
referring to breaking down of molecules/dismantling stores)]
Hepatic glycogenolysis and gluconeogenesis are the two pathways that release
glucose into the blood stream in the fasted state. Muscle glycogenolysis does not
contribute to this pool of glucose.
Generation of glucose 1-phosphate to be used for glycogen synthesis
increased ATP; high levels of ATP are highly regulatory of metabolic pathways
(suggests that we don't need to oxidize any more fuel products, we should be
storing them instead --> reduces activity)
Don't know?
2 of 125
Term
Which of the following best describes the structure of heme?
Give this one a try later!
A planar porphyrin ring that A helical structure that binds
binds iron magnesium
A spherical protein that binds oxygen
, A linear chain of amino acids that
binds copper
Don't know?
3 of 125
Definition
transketolase; Transketolase requires the cofactor thiamine
diphosphate and activity of the enzyme can be used as to determine
nutritional status.
Give this one a try later!
A farmer finds a cow dead in his field and notices an unusual plant nearby. Autopsy
results show an elevated level of citrate present in the cow's mitochondria. This data
collectively suggest inhibition of which of the following enzymes?
Alanine can be shuttled from the skeletal muscle to the liver where it is deaminated
to generate pyruvate. When glucagon is high, pyruvate is primarily used as a
substrate for which of the following pathways?
A patient presents to the emergency department with lactic acidosis. A
deficiency in thiamine (TPP) is suspected and this will be consistent with a
decrease in the activity of following enzymes?
A deficiency in thiamine can reduce the activity of the pyruvate dehydrogenase
complex. Under these conditions, you would expect to have a higher than normal
, blood concentration of which of the following metabolites?
Don't know?
4 of 125
Term
In the image below the blue line indicates enzyme kinetics with no
inhibitor present. Based on this information which of the following is
true?
Give this one a try later!
the enzyme will require a lower
green line shows enzyme kinetics
substrate concentration to reach 1/2
with no substrate present
vmax
green line shows enzyme
green line represents enzyme kinetics
kinetics with the addition of a
with a substrate analog
noncompetitive inhibitor
Don't know?
5 of 125
Term
