Which lipoprotein is responsible for the process of reverse cholesterol transport (the
movement of cholesterol from the peripheral tissues, back to the liver)
a. LDL
b. HDL
c. VLDL
d. Chylomicron
Give this one a try later!
, b. HDL
Phenylketonuria can be caused by an enzymatic deficiency or it can be present due to a
deficiency in which of the following required metabolic cofactors?
a. tyrosine
b. tetrahydrofolate (THF)
c. cobalamin (B12)
d. tetrahydrobiopterin (BH4)
Give this one a try later!
BH4
Deficiency of BH4 would impair phenylalanine metabolism to tyrosine and
result in phenylketonuria
A 4-year-old girl presented to the clinic with megaloblastic anemia and failure to thrive.
Urinalysis showed significant sediment with extremely high levels of orotic acid. A
deficiency in which of the following enzymes would be consistent with this presentation?
a. orotate phosphoribosyltransferase
b. carbamoyl phosphate synthetase II
c. thymidylate synthase
d. glutamyl amidotransferase
Give this one a try later!
orotate phosphoribosyl transferase
, A 22-year-old female goes on a hunger strike on a prominent corner in a city park. She
refuses all offers of food except for water through the first two weeks. Under these
conditions, there is a decreased reliance on which of the following pathways for fuel?
a. Beta oxidation
b. Lipolysis
c. Ketogenesis
d. Gluconeogenesis.
Give this one a try later!
d. Gluconeogenesis.
A 10-year-old female presents with chest pain and xanthomas over her elbows and
knees. Her father died of a heart attack at age 35. Her mother has high cholesterol. Her
physician suspects heterozygous familial hypercholesterolemia in the parents with the
homozygous disease presentation in the daughter. This disease results from mutations in
the receptor for low density lipoprotein (LDLs), or the ligand portion of its apoprotein
coat. Which of the following apoproteins might be mutated?
a. AI
b. B100
c. B48
d. Cii
e. E
Give this one a try later!
b. B100
movement of cholesterol from the peripheral tissues, back to the liver)
a. LDL
b. HDL
c. VLDL
d. Chylomicron
Give this one a try later!
, b. HDL
Phenylketonuria can be caused by an enzymatic deficiency or it can be present due to a
deficiency in which of the following required metabolic cofactors?
a. tyrosine
b. tetrahydrofolate (THF)
c. cobalamin (B12)
d. tetrahydrobiopterin (BH4)
Give this one a try later!
BH4
Deficiency of BH4 would impair phenylalanine metabolism to tyrosine and
result in phenylketonuria
A 4-year-old girl presented to the clinic with megaloblastic anemia and failure to thrive.
Urinalysis showed significant sediment with extremely high levels of orotic acid. A
deficiency in which of the following enzymes would be consistent with this presentation?
a. orotate phosphoribosyltransferase
b. carbamoyl phosphate synthetase II
c. thymidylate synthase
d. glutamyl amidotransferase
Give this one a try later!
orotate phosphoribosyl transferase
, A 22-year-old female goes on a hunger strike on a prominent corner in a city park. She
refuses all offers of food except for water through the first two weeks. Under these
conditions, there is a decreased reliance on which of the following pathways for fuel?
a. Beta oxidation
b. Lipolysis
c. Ketogenesis
d. Gluconeogenesis.
Give this one a try later!
d. Gluconeogenesis.
A 10-year-old female presents with chest pain and xanthomas over her elbows and
knees. Her father died of a heart attack at age 35. Her mother has high cholesterol. Her
physician suspects heterozygous familial hypercholesterolemia in the parents with the
homozygous disease presentation in the daughter. This disease results from mutations in
the receptor for low density lipoprotein (LDLs), or the ligand portion of its apoprotein
coat. Which of the following apoproteins might be mutated?
a. AI
b. B100
c. B48
d. Cii
e. E
Give this one a try later!
b. B100
