- 300-sUc
yg tength of smal! tntertne
’ Snal intestne
renmining distalbol.
proximal o'l.
(Je Jenum (\leurm)
wider diamete Thicker g more taty meeotery
thic ker avall (laxge og9rgates af symphnale
bronine nt mucasal foldg)
called a
alled as Walwalae Conniventes Peues'h Patches
’ Blend gupply -axterial -iupoier muateic antery
Weno
-supena merotec vein,
retoed tain fom Srnatl înteshne -ts usually felt n
'!.
Pesiumiltcal acgton
Crohns Drsease
(aukea Regind Enteih)
befiniion! tronsmur)
Crohn's os i a chronic ful thicknes tnflammatoy process that
an offect any part ef qT fom aips to anal margin, pachcuday
ileun ¿colop
,female > male Mesite:-Temminal Ilen
a5-40
Bimalal age distbutten
Ekalogy
’ Dret hgh n ae fned food stu fs
(Note:
Sraoktng imp alsle factd Groking- proleckive
fiost degzue oelahves factd in uleerahve
meng 24 twins colitis)
’ NDDaCARD IS Qe gene(l frameshift mutathiers)
Micaobe:. Myccbacteeiym paratubevulois & atiptal mycckactoria
toral peomeaklity
4d gut mucosal
44 paiage ot luminal, anttgens
stimulate eell medteated infammatoy esponse
telease of pro -inflommatoay eytokineg
TL-9 TNF
all3)
fnvowes lransrhur nfammation
Intestina
aalla Granubma fomation (atoncaieat
edemaof ranutorna
muco&abo eKcetive tissue Aestetia
uter °eas
ulcerahionw NEAR SNALE LIKt bLCeRS
appearsas
"Cotblestora
kubruokal fbrois hypetrophy
me meuscedaots propria
, feols ke Thkkening cf intestinal wall (Hose pfpe patten)
RUBREP
Stnctuee fomator
nasrw
later staqes -fistula foomaton CHose-plpe patem
SKIP LesloNS are characterish'e.
luterteut
post pranadial abdomfnal coltcky paio
mld dfahea- foY many months,
’ mfd fenee, wtloss
palpobte in ont.iliac fata.
- atender mass mayl my nof be
’ (n chronic cael g
'-obstectve cymptomi
&stula fomatiente-entenc fistalae
tntertoop tstulae
Extraintestina mehifestatong
Gleo-siqreid frshalae
J
resuts in
in profue
dianhea.
elated to de
(RecfunSpared in Crohns
activity Unneloted to
anemio ds acthihy
Enythena rodotom Gall stune
Pyodema gangrenosom
Adthrethy
eyecompliatins (iriti lreitia) fsleroingingcholaugihis
chronic acive hepaiths
Aphthous ulleration Sacvo?lffis
Arnylctos