NR505 EXAM QUESTIONS WITH CORRECT
ANSWERS 2025
SignsNandNsymptomsNofNhypothyroidismN-NCORRECTNANSWERN-
FaceNisNpale,Npuffy,NandNexpressionless.SkinNisNcoldNandNdry.hairNisNbrittle,NandNhairNlossNoccurs.He
artNrateNandNtemperatureNareNlowered.NTheNpatientNhasNlethargy,Nfatigue,NandNintoleranceNtoNcol
d.NMentationNmayNbeNimpaired.
SignsNandNsymptomsNofNhyperthyroidismN-NCORRECTNANSWERN-
HeartNRateNisNRapid;NPossibleNarrhythmia/angina.
Nervousness,Ninsomnia,NrapidNthoughtNflow,NandNrapidNspeech
SkeletalNmusclesNmayNweakenNandNatrophy.
MetabolicNrateNisNraised,NresultingNinNincreasedNheatNproduction,NincreasedNbodyNtemperature,Ni
ntoleranceNtoNheat,NandNskinNthatNisNwarmNandNmoist.
WeightNlossNoccursNifNcaloricNintakeNfailsNtoNmatchNtheNincreaseNinNmetabolicNrate.
SevereNhypothyroidismN-NCORRECTNANSWERN-Myxedema
HypothyroidNTreatmentN-NCORRECTNANSWERN-
LevothyroxineNisNtheNdrugNofNchoiceNforNmostNpatientsNwhoNrequireNthyroidNhormoneNreplaceme
nt.
LevothyroxineN(Synthroid)NTherapeuticNGoalN-NCORRECTNANSWERN-
ResolutionNofNsignsNandNsymptomsNofNhypothyroidismNandNrestorationNofNnormalNlaboratoryNvalu
esNforNserumNthyroid-stimulatingNhormoneN(TSH)NandNfreeNthyroxineN(T4).
MajorNformsNofNhyperthyroidismN-NCORRECTNANSWERN-
GravesNdiseaseNandNtoxicNnodularNgoiterN(alsoNknownNasNPlummerNdisease).
, Grave'sNdiseaseN-NCORRECTNANSWERN-
MostNcommonNcauseNofNexcessiveNthyroidNhormoneNsecretion
WhatNadjunctiveNtherapyNisNgoodNtoNprescribeNtoNcontrolNsymptomsNofNhyperthyroidismNotherNth
anNthyroidNspecificNmedications?N-NCORRECTNANSWERN-β-
BlockersNandNnonradioactiveNiodineNmayNbeNusedNasNadjunctiveNtherapy.
β-BlockersNsuppressNtachycardiaNbyNblockingNβ-
receptorsNonNtheNheart.NNonradioactiveNiodineNinhibitsNsynthesisNandNreleaseNofNthyroidNhormon
es.
MonitoringNneedsNandNintervalsNforNLevothyroxineN-NCORRECTNANSWERN-CheckNTSHN6-
8NweeksNafterNinitiatingNtherapyNandNafterNanyNdosageNchange.
CheckNTSHNatNleastNonceNaNyearNafterNserumNTSHNisNstabilized.
HyperthyroidNTreatmentN-NCORRECTNANSWERN-thionamideNdrugs—
methimazoleNandNpropylthiouracilN(PTU)—suppressNsynthesisNofNthyroidNhormones.
MethimazoleNTherapeuticNGoalN-NCORRECTNANSWERN-
(1)NreductionNofNthyroidNhormoneNproductionNinNGraves'Ndisease,N(2)NcontrolNofNhyperthyroidismN
untilNtheNeffectsNofNradiationNonNtheNthyroidNbecomeNmanifest,N(3)NsuppressionNofNthyroidNhormo
neNproductionNbeforeNsubtotalNthyroidectomy,N(4)NtreatmentNofNthyrotoxicNcrisis.
MonitoringNneedsNandNintervalsNforNMethimazoleN-NCORRECTNANSWERN-
CheckNCBCNwithNdifferentialNifNsignsNorNsymptomsNofNinfection.NCheckNLFTsNifNsignsNorNsymptomsN
ofNliverNdysfunction.
HighNRiskNPatientsNforNMethimazoleN-NCORRECTNANSWERN-
ShouldNbeNavoidedNinNtheNfirstNtrimesterNofNpregnancy.
ANSWERS 2025
SignsNandNsymptomsNofNhypothyroidismN-NCORRECTNANSWERN-
FaceNisNpale,Npuffy,NandNexpressionless.SkinNisNcoldNandNdry.hairNisNbrittle,NandNhairNlossNoccurs.He
artNrateNandNtemperatureNareNlowered.NTheNpatientNhasNlethargy,Nfatigue,NandNintoleranceNtoNcol
d.NMentationNmayNbeNimpaired.
SignsNandNsymptomsNofNhyperthyroidismN-NCORRECTNANSWERN-
HeartNRateNisNRapid;NPossibleNarrhythmia/angina.
Nervousness,Ninsomnia,NrapidNthoughtNflow,NandNrapidNspeech
SkeletalNmusclesNmayNweakenNandNatrophy.
MetabolicNrateNisNraised,NresultingNinNincreasedNheatNproduction,NincreasedNbodyNtemperature,Ni
ntoleranceNtoNheat,NandNskinNthatNisNwarmNandNmoist.
WeightNlossNoccursNifNcaloricNintakeNfailsNtoNmatchNtheNincreaseNinNmetabolicNrate.
SevereNhypothyroidismN-NCORRECTNANSWERN-Myxedema
HypothyroidNTreatmentN-NCORRECTNANSWERN-
LevothyroxineNisNtheNdrugNofNchoiceNforNmostNpatientsNwhoNrequireNthyroidNhormoneNreplaceme
nt.
LevothyroxineN(Synthroid)NTherapeuticNGoalN-NCORRECTNANSWERN-
ResolutionNofNsignsNandNsymptomsNofNhypothyroidismNandNrestorationNofNnormalNlaboratoryNvalu
esNforNserumNthyroid-stimulatingNhormoneN(TSH)NandNfreeNthyroxineN(T4).
MajorNformsNofNhyperthyroidismN-NCORRECTNANSWERN-
GravesNdiseaseNandNtoxicNnodularNgoiterN(alsoNknownNasNPlummerNdisease).
, Grave'sNdiseaseN-NCORRECTNANSWERN-
MostNcommonNcauseNofNexcessiveNthyroidNhormoneNsecretion
WhatNadjunctiveNtherapyNisNgoodNtoNprescribeNtoNcontrolNsymptomsNofNhyperthyroidismNotherNth
anNthyroidNspecificNmedications?N-NCORRECTNANSWERN-β-
BlockersNandNnonradioactiveNiodineNmayNbeNusedNasNadjunctiveNtherapy.
β-BlockersNsuppressNtachycardiaNbyNblockingNβ-
receptorsNonNtheNheart.NNonradioactiveNiodineNinhibitsNsynthesisNandNreleaseNofNthyroidNhormon
es.
MonitoringNneedsNandNintervalsNforNLevothyroxineN-NCORRECTNANSWERN-CheckNTSHN6-
8NweeksNafterNinitiatingNtherapyNandNafterNanyNdosageNchange.
CheckNTSHNatNleastNonceNaNyearNafterNserumNTSHNisNstabilized.
HyperthyroidNTreatmentN-NCORRECTNANSWERN-thionamideNdrugs—
methimazoleNandNpropylthiouracilN(PTU)—suppressNsynthesisNofNthyroidNhormones.
MethimazoleNTherapeuticNGoalN-NCORRECTNANSWERN-
(1)NreductionNofNthyroidNhormoneNproductionNinNGraves'Ndisease,N(2)NcontrolNofNhyperthyroidismN
untilNtheNeffectsNofNradiationNonNtheNthyroidNbecomeNmanifest,N(3)NsuppressionNofNthyroidNhormo
neNproductionNbeforeNsubtotalNthyroidectomy,N(4)NtreatmentNofNthyrotoxicNcrisis.
MonitoringNneedsNandNintervalsNforNMethimazoleN-NCORRECTNANSWERN-
CheckNCBCNwithNdifferentialNifNsignsNorNsymptomsNofNinfection.NCheckNLFTsNifNsignsNorNsymptomsN
ofNliverNdysfunction.
HighNRiskNPatientsNforNMethimazoleN-NCORRECTNANSWERN-
ShouldNbeNavoidedNinNtheNfirstNtrimesterNofNpregnancy.