MYASTHENIA
GRAVIS
By: Hiren K Gehloth
F.Y.M.Sc Nursing
Govt.College Of
Nursing,Abad(GINERA
)
,INTRODUCTION
Myasthenia gravis means “grave muscle
weakness’ or “weakness of the voluntary or
striated muscles of the body”.
, Myasthenia gravis (MG) is a relatively rare autoimmune
disorder in which antibodies form against nicotinic
acetylcholine (ACh) postsynaptic receptors at the
neuromuscular junction (NMJ) of the skeletal muscles. It
is a type-II hypersensitivity immune response.
The basic pathology is a reduction in the number of ACh
receptors (AChRs) at the postsynaptic muscle membrane
brought about by an acquired autoimmune reaction
producing anti-AChR antibodies.
The reduction in the number of AChRs results in a
characteristic pattern of progressively reduced muscle
strength with repeated use and recovery of muscle
strength after a period of rest.
,
GRAVIS
By: Hiren K Gehloth
F.Y.M.Sc Nursing
Govt.College Of
Nursing,Abad(GINERA
)
,INTRODUCTION
Myasthenia gravis means “grave muscle
weakness’ or “weakness of the voluntary or
striated muscles of the body”.
, Myasthenia gravis (MG) is a relatively rare autoimmune
disorder in which antibodies form against nicotinic
acetylcholine (ACh) postsynaptic receptors at the
neuromuscular junction (NMJ) of the skeletal muscles. It
is a type-II hypersensitivity immune response.
The basic pathology is a reduction in the number of ACh
receptors (AChRs) at the postsynaptic muscle membrane
brought about by an acquired autoimmune reaction
producing anti-AChR antibodies.
The reduction in the number of AChRs results in a
characteristic pattern of progressively reduced muscle
strength with repeated use and recovery of muscle
strength after a period of rest.
,
