Summary Role of Laboratory tests in Rheumatology

Role of Laboratory
tests in
Rheumatology
Presenters:Blen M.(R1)
Mamaru s.(R2)
Moderator: Dr Zenebe M.(neurologist
rheumatologist)

,Outline of Presentation( Part one)
▪Introduction
▪Routine diagnostic studies
▪Markers of inflammation
• Uric acid
• Acute phase reactants
▪Autoimmune markers
• Rheumatoid factor
• Anti-CCP

,Introduction
▪Rheumatologic diseases are the leading cause of disability globally
▪Underdiagnosed due to overlapping organ system involvements and lack of diagnostic tests
▪Laboratory and imaging tests make up about 5% of the information for diagnosis.
▪Common rheumatic diseases like osteoarthritis, rheumatoid arthritis and psoriatic arthritis m
be diagnosed without laboratory tests
▪Improper application of laboratory tests can result in misdiagnosis and inappropriate therap

, Ideal Rheumatologic test
▪All patients with disease have a positive test, all with out have a negative tests
▪All patients with positive tests result have disease, all with negative do not
▪Test results correlate with organ system involvement
▪Tests correlate with disease activity


▪No screening test is ideal for detecting rheumatic diseases