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1. 7 alkylating agents for cancer treatment - ANSWER 1. Carbonation -
paraplatin
2. Cisplatin- platinol
3. Cyclophosphamide-cytoxan
4. Dacarbazine-DTIC
5. Ifosfamide- ifex
6. Mechlorethamine hydrochloride- mustargen
7. Thiotepa- thiolpex
2. Carboplatin (Paraplatin) - ANSWER Non vesicant
Solid tumors
3. Cisplatin (Platinol) - ANSWER Irritant and vesicant
Neurblastoma
Wilms tumor
Myeloma
Lymphoma
4. Wilms tumor - ANSWER malignant tumor of the kidney occurring in
childhood
,5. Cyclophosphamide (Cytoxan) - ANSWER Non vesicant
Lymphatic leukemia
Hodgkins/ non hodgkins
6. 3 cancer drugs that used to prepare bone marrow - ANSWER Carboplatin
Cyclophosphamide
Thiotepa
7. Dacarbazine (DTIC) - ANSWER Irritant
Melanoma
Soft tissue sarcomas
Neuroblastoma
Hodgkins
8. Ifosfamide (Ifex) - ANSWER Non vesicant
Lung cancer
Sarcoma
Non Hodgkins
9. Mechlorethamine (Mustargen) - ANSWER Vesicant
Chronic lymphocytic
Myelogenous leukemia
,Hodgkins
10. Thiotepa (Thioplex) - ANSWER Non vesicant
Hodgkins
Lymphoma
Brain
Breast
Ovarian
Bladder
11. Isotonic dehydration - ANSWER Most common in children
Loss of fluid and sodium in equal proportions
Most fluid is lost from extracellular compartment
Cause by vomiting, NPO pre and post op
12. Serum Osmolality (normal range) - ANSWER 275-295 mOsm/kg
13. 5. Antimetabolites - ANSWER 1. Cytarabine- cytosar U
2. Fludatabine- fluradara
3. Methotrexate- mediate Aq
4. Fluorouracil-5fU
5. Gemcitabine- gemzar
, All non vesicants
14. Antimetabolites - ANSWER chemicals that prevent cell division by
inhibiting formation of substances necessary to make DNA; used in cancer
chemotherapy
15. Immune Modulators - ANSWER Used to modify actions of the immune
system. Stimulate or suppress
16. Most common immune modulator - ANSWER Immune globulin 4.
Sandoglublin
Restores immunoglobulin g levels
17. Plicamycin (Mithracin) - ANSWER Controls hypercalcemia
Can cause hypocalcemia- muscle cramps, nosebleeds, weakness
18. Epidural analgesia - ANSWER Analgesia injected into the epidural space
outside the dura mater to relieve pain.
Acute pain or chronic pain
19. Epidural anesthesia - ANSWER regional anesthesia produced by injecting
medication into the epidural space of the lumbar or sacral region of the spine