•It affects women in reproductive ag
progress to malignant forms which t
•The malignant form so fit is curable
discovered in early stages
DEFINITION:
-GTD refer to the spectrum of proli
pregnancy. In GTD abnormal growth
It is charachterized by production o
is used as amarker for diagnosis and
ETIOLOGY:
-Cause is not definitely known but:
• It is highest in teenagers and >35.
• Race and ethnic group.
• Inadequate diet low protein
• Blood group A ,AB.
• Cytogenitic abnormality :complete mole is 46xx karyotype (father origin).
• History of priormole pregnancy
PATHOLOGY
• It is principally disease of chorion
•Death of ovum or failure of embryo to growth is essential to develop complete
vesicular mole.
NAKED EYE:
• uterus is filled with clusters of cysts of varying size
• No trace of embryo or amniotic sac.
MICROSCOPICALLY:-
• Proliferation of cys to- cyncytio trophoblast.
progress to malignant forms which t
•The malignant form so fit is curable
discovered in early stages
DEFINITION:
-GTD refer to the spectrum of proli
pregnancy. In GTD abnormal growth
It is charachterized by production o
is used as amarker for diagnosis and
ETIOLOGY:
-Cause is not definitely known but:
• It is highest in teenagers and >35.
• Race and ethnic group.
• Inadequate diet low protein
• Blood group A ,AB.
• Cytogenitic abnormality :complete mole is 46xx karyotype (father origin).
• History of priormole pregnancy
PATHOLOGY
• It is principally disease of chorion
•Death of ovum or failure of embryo to growth is essential to develop complete
vesicular mole.
NAKED EYE:
• uterus is filled with clusters of cysts of varying size
• No trace of embryo or amniotic sac.
MICROSCOPICALLY:-
• Proliferation of cys to- cyncytio trophoblast.
