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NR548-
NR 548 EXAM 1 NEWEST LATEST UPDATE 2024-
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2025 PSYCHIATRIC ASSESSMENT FOR THE PSYC
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HIATRIC-MENTAL HEALTH NURSE j j
PRACTITIONER REVIEWWEEK 1&2QUESTIONS WIT j j j j
H CORRECT VERIED ANSWERS GRADED A+
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Explain the clinical signifcance of the Stystematic Treatme
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nt Enhancement Program for Bipolar Disorder: STEP-BD) -
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ANSWER >>>As more contempts are tried with SSRIs to rel
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ieve depressive symptoms, the client becomes more treat
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ment resistant leading to poor outcomes.
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Explain the clinical significance of the Sequenced Treatmen
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t Alternative to Relieve Depression STAR D -
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ANSWER >>>Strong behavioral therapy combined with me
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dications lead to 30% better outcomes as compared to mon
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otherapy or medication or therapy alone.
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Describe the mechanism of action of Typical Antipsychoti
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cs - j
ANSWER >>>Blocking D2 receptors in the mesolimbic and
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mesocortical
The Blocking D2 receptors in the mesolimbic and mesocorti
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cal tract - j j
ANSWER >>>tract reducing positive symptoms of psychosis
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, does effect the negative symptoms of the disorder, can cre
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ate EPS symptoms in the nigro-striatal tract,
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Nigrostriatal - j
ANSWER >>>involved with muscular movement
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Mesolimbic - j
ANSWER >>>source of visual hallucinations and auditory ha
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llucinations,
Mesocortical - j
ANSWER >>>mesocortical area holds affective symptoms
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,
Second generation antipsychotics are pharmacology dire
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cted to - j j
ANSWER >>>blocking both D2 and 5HT receptors in the br
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ain and also relieve the negative symptoms of psychosi
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down regulation blocking Alpha ! receptors - ANSWER
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>>>Orthostatic hypotension and dizziness which comes
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down regulation of blocking Muscarinic and Histamine recep
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tors - ANSWER >>>Weight gain, dizziness
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serontin down regulation in the gut - ANSWER j j j j j j j
>>>constipation
Neuroleptic malignant syndrome - j j j
ANSWER >>>cause by increased medication changes or tre
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atment naive patients j j
What are notable side effects of Clozapine - ANSWER
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>>>Induced by cigarette smoking which is through the 1A2 j j j j j j j j
pathway
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Recommended dosing schedule for clozapine - ANSWER j j j j j j
>>>Start at 12.5 first day, j j j j
then in divide doses of 25-50 mg/day up to 300-
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400 mg per day.
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Clozapine maxes - j j
ANSWER >>>Maximum dose is 900 mg per day.
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No single dose should exceed 450 mg
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Clozapine monitoring - j j
ANSWER >>>Need to register at the clozapine website as a p
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rovider
NR548-
NR 548 EXAM 1 NEWEST LATEST UPDATE 2024-
j j j j j j j j
2025 PSYCHIATRIC ASSESSMENT FOR THE PSYC
j j j j j
HIATRIC-MENTAL HEALTH NURSE j j
PRACTITIONER REVIEWWEEK 1&2QUESTIONS WIT j j j j
H CORRECT VERIED ANSWERS GRADED A+
j j j j j
Explain the clinical signifcance of the Stystematic Treatme
j j j j j j j
nt Enhancement Program for Bipolar Disorder: STEP-BD) -
j j j j j j j
ANSWER >>>As more contempts are tried with SSRIs to rel
j j j j j j j j j j
ieve depressive symptoms, the client becomes more treat
j j j j j j j
ment resistant leading to poor outcomes.
j j j j j
Explain the clinical significance of the Sequenced Treatmen
j j j j j j j
t Alternative to Relieve Depression STAR D -
j j j j j j j
ANSWER >>>Strong behavioral therapy combined with me
j j j j j j j
dications lead to 30% better outcomes as compared to mon
j j j j j j j j j
otherapy or medication or therapy alone.
j j j j j
,2j|jPj aj gj e
Describe the mechanism of action of Typical Antipsychoti
j j j j j j j
cs - j
ANSWER >>>Blocking D2 receptors in the mesolimbic and
j j j j j j j j j
mesocortical
The Blocking D2 receptors in the mesolimbic and mesocorti
j j j j j j j j
cal tract - j j
ANSWER >>>tract reducing positive symptoms of psychosis
j j j j j j j
, does effect the negative symptoms of the disorder, can cre
j j j j j j j j j j
ate EPS symptoms in the nigro-striatal tract,
j j j j j j
Nigrostriatal - j
ANSWER >>>involved with muscular movement
j j j j j
Mesolimbic - j
ANSWER >>>source of visual hallucinations and auditory ha
j j j j j j j j
llucinations,
Mesocortical - j
ANSWER >>>mesocortical area holds affective symptoms
j j j j j j
,
Second generation antipsychotics are pharmacology dire
j j j j j
cted to - j j
ANSWER >>>blocking both D2 and 5HT receptors in the br
j j j j j j j j j j
ain and also relieve the negative symptoms of psychosi
j j j j j j j j
down regulation blocking Alpha ! receptors - ANSWER
j j j j j j j
,3j|jPj aj gj e
>>>Orthostatic hypotension and dizziness which comes
j j j j j
, 4j|jPj aj gj e
down regulation of blocking Muscarinic and Histamine recep
j j j j j j j
tors - ANSWER >>>Weight gain, dizziness
j j j j j
serontin down regulation in the gut - ANSWER j j j j j j j
>>>constipation
Neuroleptic malignant syndrome - j j j
ANSWER >>>cause by increased medication changes or tre
j j j j j j j j
atment naive patients j j
What are notable side effects of Clozapine - ANSWER
j j j j j j j j
>>>Induced by cigarette smoking which is through the 1A2 j j j j j j j j
pathway
j
Recommended dosing schedule for clozapine - ANSWER j j j j j j
>>>Start at 12.5 first day, j j j j
then in divide doses of 25-50 mg/day up to 300-
j j j j j j j j j
400 mg per day.
j j j
Clozapine maxes - j j
ANSWER >>>Maximum dose is 900 mg per day.
j j j j j j j j
No single dose should exceed 450 mg
j j j j j j
Clozapine monitoring - j j
ANSWER >>>Need to register at the clozapine website as a p
j j j j j j j j j j j
rovider