PHARM GI DRUGS LATEST TEST 3 COMPLETE ACTUAL TEST 3 QUESTIONS AND CORRECT VERIFIED SOLUTIONS (A NEW UPDATED VERSION)

NURS 5334 PHARM STUDY GUIDE QUIZ 1 LATEST UPDATEBE
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ST EXAM SOLUTION GRADED A+(2021/2022)
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MODULE 1 u



• What are the BON rules and regulations for prescriptive authority fort
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he advance practice nurse?
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• Texas is very restricted u u u



• Describe the pharmacokinetic processes of absorption, distribution,
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metabolism and elimination and how differences in these areas affect
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drug action.u



• Absorption
• Drug’s movement from the site of administration into theb
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lood.
• Distribution
• Drug’sumovementufromutheublooduintoutheuinterstitialuspaceuo

f tissues and from there into cells.
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• Metabolism
• Biotransformationuisutheuenzymaticallyumediatedualterationuofu

drug structure. u



• Elimination
• Combination of metabolism and excretion u u u u



• Discuss the impact of food on drug absorption, drug metabolism and ond
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rug toxicity and action—as well as the timing of drug administration.
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LIFESPAN
• Hepatic metabolism and GFR increase during pregnancy, dosages ofs
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ome drugs may need to be increased.
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• Rate of albumin to water decreases
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• Thirdutrimester:uRenalublooduflowuisudoubleduandurenalue

xcretion is accelerated (drugs excreted rapidly)
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• Tone and mobility of bowel decrease
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NURS 5334 PHARM STUDY GUIDE QUIZ 1 LATEST UPDATEBE
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ST EXAM SOLUTION GRADED A+(2021/2022)
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,NURS 5334 PHARM STUDY GUIDE QUIZ 1 LATEST UPDATEBE
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ST EXAM SOLUTION GRADED A+(2021/2022)
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• Prolongation of drug effects Total (½ life increases)
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Understand stages of development in pregnancy
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NURS 5334 PHARM STUDY GUIDE QUIZ 1 LATEST UPDATEBE
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ST EXAM SOLUTION GRADED A+(2021/2022)
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, NURS 5334 PHARM STUDY GUIDE QUIZ 1 LATEST UPDATEBE
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ST EXAM SOLUTION GRADED A+(2021/2022)
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• Conception: through week 2 u u u



• Embryonic period: week 3-week 8 u u u u



a) Gross malformations can be produced by teratogens
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• Fetal period: week 9-delivery
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• Understand pregnancy labeling
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• 3 categories now
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a)u Pregnancy,ulactation,umaleu&ufemaleureproductiveupotentia

l
• How do you decrease risk in the infant during breastfeeding?
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• Takeumedsuimmediatelyuafterubreastfeeding,uavoidudrugsuthatuh

ave long half-
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lives, choose drugs that tend to be excluded from milk, avoid
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drugs that are known to be hazardous.
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• How do pediatric patients differ in their response to medications?
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• Absorption
a) Oral?

• Neonates: drug remain in the stomach longer whi
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ch increases the levels, low acidity can affectthe a
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bsorption of acid labile drugs u u u u



b) Parenteral?

• Reponses are slow and erratic. u u u u



• Infancy: absorption is more rapid than in neonates
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& adultsu



• Best avoided in infants
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c) Transdermal?

• Greater skin permeability which increases top
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ical drug absorption and increases the riskfor t
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NURS 5334 PHARM STUDY GUIDE QUIZ 1 LATEST UPDATEBE
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ST EXAM SOLUTION GRADED A+(2021/2022)
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, NURS 5334 PHARM STUDY GUIDE QUIZ 1 LATEST UPDATEBE
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ST EXAM SOLUTION GRADED A+(2021/2022)
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oxicity
• Distribution
a) Proteinubinding




NURS 5334 PHARM STUDY GUIDE QUIZ 1 LATEST UPDATEBE
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ST EXAM SOLUTION GRADED A+(2021/2022)
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