MOLBIO EXAM 1 2025 QUESTIONS
AND ANSWERS 100% PASS
What did Mendel discover? - ✔✔Heritable traits/heredity
What did Chargaff propose? - ✔✔Base Pairing
What did Miescher discover? - ✔✔Nucleic acids are a major part of the cell
What did Griffith discover? - ✔✔-DNA encodes genes
-Genes are transferable
What data did Watson and Crick base their model on? - ✔✔Franklin and Wilkin's
model
What was concluded from Griffith's experiment? - ✔✔DNA confers traits
What are the types of secondary structure? - ✔✔Alpha helices and beta sheets
How are these secondary structures stabilized? - ✔✔Hydrogen bonding
What are the two main models of how substrates fit into an enzyme? - ✔✔-Lock and
key
-Induced fit
What is an allosteric effector? - ✔✔A molecule that binds to sites on the enzyme distinct
from the catalytic site
COPYRIGHT © 2025 BY GRACE AMELIA, ALL RIGHTS RESERVED 1
, Cytosine and thymidine are? - ✔✔Pyrimidines
What does adenine pair with? - ✔✔Thymidine
How many bases are in an A form helix? - ✔✔11
What direction does a Z helix turn? - ✔✔Left
What direction does a B helix turn? - ✔✔Right
Melting point increases with more of which base pairing? Why? - ✔✔G + C; there are 3
hydrogen bonds instead of 2
What direction does replication occur in? - ✔✔5' to 3'
What does topoisomerase I do? - ✔✔Relaxes supercoils within the genome
What does MukB do? - ✔✔-Organizes and compacts DNA
-ATP-dependent chromosome partitioning during cell division
How many nucleic acids are coiled around a histone? - ✔✔146 Base Pairs
What does the histone protein H1 do? - ✔✔Holds DNA in place around the core histone
What amino acid in Topoisomerase I helps induce nicks in the phosphate backbone? -
✔✔Tyrosine
How are the ends of linear genomes stabilized? - ✔✔Telomeres
What are the four types of RNA? - ✔✔-mRNA
-tRNA
-rRNA
-microRNA
COPYRIGHT © 2025 BY GRACE AMELIA, ALL RIGHTS RESERVED 2
AND ANSWERS 100% PASS
What did Mendel discover? - ✔✔Heritable traits/heredity
What did Chargaff propose? - ✔✔Base Pairing
What did Miescher discover? - ✔✔Nucleic acids are a major part of the cell
What did Griffith discover? - ✔✔-DNA encodes genes
-Genes are transferable
What data did Watson and Crick base their model on? - ✔✔Franklin and Wilkin's
model
What was concluded from Griffith's experiment? - ✔✔DNA confers traits
What are the types of secondary structure? - ✔✔Alpha helices and beta sheets
How are these secondary structures stabilized? - ✔✔Hydrogen bonding
What are the two main models of how substrates fit into an enzyme? - ✔✔-Lock and
key
-Induced fit
What is an allosteric effector? - ✔✔A molecule that binds to sites on the enzyme distinct
from the catalytic site
COPYRIGHT © 2025 BY GRACE AMELIA, ALL RIGHTS RESERVED 1
, Cytosine and thymidine are? - ✔✔Pyrimidines
What does adenine pair with? - ✔✔Thymidine
How many bases are in an A form helix? - ✔✔11
What direction does a Z helix turn? - ✔✔Left
What direction does a B helix turn? - ✔✔Right
Melting point increases with more of which base pairing? Why? - ✔✔G + C; there are 3
hydrogen bonds instead of 2
What direction does replication occur in? - ✔✔5' to 3'
What does topoisomerase I do? - ✔✔Relaxes supercoils within the genome
What does MukB do? - ✔✔-Organizes and compacts DNA
-ATP-dependent chromosome partitioning during cell division
How many nucleic acids are coiled around a histone? - ✔✔146 Base Pairs
What does the histone protein H1 do? - ✔✔Holds DNA in place around the core histone
What amino acid in Topoisomerase I helps induce nicks in the phosphate backbone? -
✔✔Tyrosine
How are the ends of linear genomes stabilized? - ✔✔Telomeres
What are the four types of RNA? - ✔✔-mRNA
-tRNA
-rRNA
-microRNA
COPYRIGHT © 2025 BY GRACE AMELIA, ALL RIGHTS RESERVED 2
