Answers
.42-year-old female with history of severe rheumatoid arthritis requiring
multiple medications follows up with her primary care physician assistant. She
has been doing well on her current medication regimen but has been having
some mild headaches. Her blood pressure today is 170/92 P = 82, T = 96.2˚F. She
denies any previous history of hypertension. Which of the following
medications that she is taking is most likely to be contributing to her
hypertension?
A
methotrexate
B
cyclosporine
C
acetaminophen
D
hydrocodone
E
fexofenadine - ANSWER-B
The correct answer is (B). Cyclosporine, an immunosuppressant, is known to
cause hypertension as a potential side effect and should be considered as a
potential secondary cause of secondary hypertension. Methotrexate,
acetaminophen, and fexofenadine are not known to cause secondary
hypertension. Hydrocodone may actually cause hypotension as a potential
adverse reaction.
,.A 12 year-old African-American male with a history of sickle cell disease
presents to the clinic for routine follow up. A peripheral smear is performed.
Which of the following best describes the cause of the abnormality pictured in
the patient's peripheral smear? (note photo taken from figure 29-12 in
Harrison's)
A
Absent or non-functioning spleen
B
Failure of nuclear maturation
C
Intravascular hemolysis
D
Lead intoxication - ANSWER-The Correct Answer is: A
Howell-Jolly bodies are noted in the peripheral smear and result from the lack
of removal of nuclear material due to an absent or non-functioning spleen.
Failure of nuclear maturation (B) produces macrocytosis, intravascular
hemolysis (C) leads to the creation of schizocytes, lead intoxication (D) and
thalassemia cause basophilic stippling, and uremia (E) is associated with Burr
cells.
.A 12-year-old boy is being seen for concerns of development of breast tissue.
Upon physical exam, he is noted to have a firm, slightly tender mass under the
left areola. What is the most appropriate action at this time?
A
,referral to pediatric surgery for resection
B
measurement of serum hCG
C
measurement of testosterone and estrogen levels
D
reassurance and observation - ANSWER-The Correct Answer is: D
Type 1 idiopathic gynecomastia in adolescent men presents with a firm mass
under the areola ("breast bud") typically during sexual maturation stages (SMR),
stages II to III. This is a result of normal estrogen and androgen activity at the
breast tissue level. Appropriate action is observation and to reassure the patient
that the condition will likely resolve in 1 to 2 years. (Kaplan, 2009, p. 120)
Kaplan DW , Love-Osborne KA. Adolescence. In: Hay WW , Levin MJ ,
Sondheimer JM, et al., eds. Current Pediatric Diagnosis and Treatment. 19th ed.
New York, NY: McGraw-Hill; 2009.
.A 14-year-old female patient presents to your family practice clinic having
received a 1% total body surface area first and second degree burn to the left
forearm. Of the following, what would you recommend for your patient?
A
Deroof any blisters, apply bacitracin topically, and prescribe pain medication,
with follow-up in 48 hours,
B
Deroof any blisters, apply silver sulfadiazine topically, and prescribe pain
medication, with follow-up in 48 hours.
, C
Leave any blisters intact, apply bacitracin topically, and prescribe pain
medication, with follow-up in 48 hours.
D
Leave any blisters intact, apply silver sulfadiazine topically, and prescribe pain
medication, with follow-up in 48 hours,
E
Refer to the emergency department immediately, - ANSWER-The Correct
Answer is: C
Unless a critical surface (face, genitalia or hands) is involved, first and second
degree burns may be treated in the outpatient setting. Blisters may be left
intact as a physiologic dressing, and deroofed after they rupture. The patient
requires tetanus prophylaxis and a topical antibiotic cream, usually either silver
sulfadiazine or, preferably, bacitracin. Sulfadiazine may permanently stain skin,
so use it cautiously in potentially exposed skin areas for cosmetic reasons.
.A 15-year-old female comes into your office with multiple symptoms of an
eating disorder. What is the single feature that would lead you to diagnose
anorexia rather than bulimia or binge eating disorder?
A
Binge eating behaviors
B
Compensatory measures such as purging
C
Preoccupation with body weight