Advanced Pharmacology Final -
m m m
Practice Quiz Questions Latest with Complete
m m m m m m
Solutions m
Escitaloprammmaymcause mserious,mpotentiallyfatalmreactionsmwhenmusedmwithm
.m (selectmal
lmthatmapply)
{{Ans-mDuloxetine, mamitriptilyne,msertraline,mSt.mJohn'smWort
Mixingmtwomserotoninmagentsmcanmcause mserotoninmsyndrome.
The mtherapeuticmeffectsmof mimipramine mdevelopmoverm .
{{Ans-m Severalm weeks
The mFDA-approvedmindicationsmformfluoxetine minclude:m(selectmallmthatmapply)
{{Ans-mObsessive mcompulsive mdisorder,mmajormdepressive mdisorder,mbulimiamnervosa
Takingmfoodmwithmbuspirone m altersmabsorption.m{{Ans-mFalse
Maym be mtakenmwithmfoodmtom minimize mgastricmirritation
Venlafaxine mismextensivelymmetabolizedmonmfirstmpassmthroughmthe m .m {{Ans-mLiver
Signsmandm symptomsmofmlithiummtoxicityminclude:m(selectmallmthatmapply)m {{Ans-mSlurredmspeech,mdrowsiness
Valproate macidmhasmFDA-approvedmindicationsmfor:m(selectmallmthatmapply)
{{Ans-mAcute mmania,msimple mandmcomplex mabsence mseizures,mpreventionmof mmigraine mheadaches
,Atomoxetine mselectivelym mthe m presynapticmreuptake mofmnorepinephrine mresultingminma(n)
m attention m span.
{{Ans-m Inhibits,mimproved
Phenelzine mdoesmnotmneedmtombemdiscontinuedmseveralmdaysmbefore melectivemsurgerymthatmrequiresman
esthesia.m{{Ans-mFalse
Bupropionmcanmbe m usedmformsmokingmcessation.m{{Ans-mTrue
Methylphenidate mismnotmeffective mformnarcolepticmpatients.m {{Ans-mFalse
Clozapine mmaymcause:m(selectmallmthatmapply) m {{Ans-mSyncope,morthostaticmhypotension, mcardiacmarrest
Causesmbradycardiamwhichmcouldmleadmtomsyncope mandmcardiacm arrest
Administeringmrisperidone mwithmlevodopamismcontraindicated.m {{Ans-mTrue
Itm decreasesmthe meffectsmof mlevodopa
The m m formm of mziprasidone mismfrequentlymusedmformcontrolmofmacutelymagitatedmpatients.
{{Ans-m Intramuscularm(IM)
Anticonvulsantsmare mfrequentlymusedmasmmoodmstabilizersmformthemtreatmentmofmmaniamandmbipolarmsp
ectrummdisordersmbecause mthey:m{{Ans-mReduce msynapticmkindling
Ampatientmwasmstartedmonmfluoxetinemformdepressionm3mdaysmago.mShe mnowmcomplainsmthatmitm"doesnm't
mhelp"m andm refusesm tom takem it.mUnderstandingm the mpsychopharmacology,m the mnurse'sm bestm firstm action
m ism to:
,{{Ans-
m Discuss m withmthem patientmthatmthesemtypesmof mmedications moftenmtakem severalmweeks mbefore mseeingm t
he mresults.
Whichmof mthe mfollowingmismamcommonmside meffectmofmbothmfirst-mandmsecond-
generationmantipsychoticmdrugs?m(selectmallmthatmapply)
{{Ans-mExtrapyramidalmside meffectsmsuchmasmpseudo-
parkinsonismmormacute mdystonia,mneurolepticmmalignantmsyndrome, mexcessive msedation
Ammale mpatientmwhomismtakingmthe msecond-
generationmantipsychoticmreportsmtomthemnursemthatmhem hasmobservedmamclearmfluidmleakingmfrommhismri
ghtmnipple mformthe mpastmmonth.mThe mnurse'smbestminitialminterventionmis:
{{Ans-mInformmthe mpatientmthatmthismcouldmbe mam side meffectmof mthe mmedication
The mphysicianmdiscussesmthe mappropriatenessmofmprescribingmamserotonin/norepinephrinemreuptake min
hibitorm(SNRI) mformampatient.mWhichmofmthe m followingmmedicationsmare minmthismcategory?
{{Ans-m Venlafaxine mandmduloxetine
Ampatientmhasmbeenmprescribedmamselective mserotoninmreuptakeminhibitorm(SSRI)mformdepression.mThe mn
urse mshouldmcounselmthe mpatientmaboutmwhichmofmthemfollowingmpossiblemsidemeffects,mamongmothers?
{{Ans-mFever,msweating,magitation,mrapidmheartbeat
Amnurse mcounselsmampatientmwhomhasmbeenmprescribedmammonoamine moxidaseminhibitorm(MAOI) mtomtre
atmdepressionmtomavoidmfoodsmcontainingmtyramine.mWhichmofmthemfollowingmfoodsmshouldmthe mpatient
m avoid?m (selectm allm thatm apply)
{{Ans-mYogurt,mtofu,mpepperoni
Ampatientmwithmseveremkidneymdiseasemismstartedmonmlithiummbymamnewmresident.mAsmthe mnurse monmdutymy
ourmbestminitialmresponse mwouldmbe mto:
{{Ans-
m Contactm the mresidentmtomremindmhimmthatmthem clientmhasmkidneym diseasemandmlithiummism contraindicat
ed
, Whichmof m the mfollowingmismgenerallymtrue mof mmedicationsmusedmtomtreatmanxietymdisorders?
{{Ans-
m Justm asmwithmdepression, mthemmostmcommonmmedications m prescribed marem serotonin m reuptake m inhibit
orsm(SSRIs) mandmselective mnorepinephrine mreuptake minhibitorsm(SNRIs).
Formwhichmonemof mthem followingmtypesmof mdrugsmismthe mconsumptionmof mgrapefruitmjuice mcontraindicated?
{{Ans-m Second-generationmantipsychotics
Psychopharmaceuticalmagentsmaremprescribedmformindividualsmwithmsubstancemusemdisordersmformallmofmthemfo
llowingmreasonsmexcept:
{{Ans-mTomelevate mthempatient'smmoodminmammannermcomparable mtomthe mactionmof m the mmisusedmsubstance
Ampatientmhasmbeenmprescribedmdisulfiram.mThe mnurse mwouldmmostmappropriatelymcounselmthe mpatientma
boutmwhichmof mthe mfollowing?
{{Ans-mAmtoxicmreactionmifmalcoholmismconsumed
Whenmampatientmismprescribedmrisperidonemformschizoaffective mdisorder,mthemnursemmustmalertmthempatie
ntmtomthe mpotentialmformneurolepticmmalignantmsyndrome.mWhichmof mthemfollowingmwouldmbemaccuratem
informationmtomgive mthe mpatient?
{{Ans-
m Neurolepticmmalignantmsyndrome m ism potentially m fatal.m Itmusuallym occursm duringm the mfirstm 2mweeksm afterm
startingmanm antipsychoticmdrugmormincreasingmthemdose mandmismcharacterizedmbymhighmfever,mmusclemstiff
ness,mparanoia,msweating,mandmlarge mchangesminmbloodmpressure.
Amclientmwithmdepressionmismtakingmphenelzine.mThe mnurse madvisesmthemclientmtomavoidmconsumingmwhic
hmfoodsmwhile mtakingmthe mmedicationm{{Ans-mYogurt
Methylphenidate mismamCNSmstimulantmandmismthe mdrugmof mchoice mformindividualsmwithmattention-
m deficit/hyperactivity m disorderm(ADHD). m The m desired m effects m of m methylphenidate m may m be m noted m as:
{{Ans-mIncreasedmattentionmspanmandmconcentration
m m m
Practice Quiz Questions Latest with Complete
m m m m m m
Solutions m
Escitaloprammmaymcause mserious,mpotentiallyfatalmreactionsmwhenmusedmwithm
.m (selectmal
lmthatmapply)
{{Ans-mDuloxetine, mamitriptilyne,msertraline,mSt.mJohn'smWort
Mixingmtwomserotoninmagentsmcanmcause mserotoninmsyndrome.
The mtherapeuticmeffectsmof mimipramine mdevelopmoverm .
{{Ans-m Severalm weeks
The mFDA-approvedmindicationsmformfluoxetine minclude:m(selectmallmthatmapply)
{{Ans-mObsessive mcompulsive mdisorder,mmajormdepressive mdisorder,mbulimiamnervosa
Takingmfoodmwithmbuspirone m altersmabsorption.m{{Ans-mFalse
Maym be mtakenmwithmfoodmtom minimize mgastricmirritation
Venlafaxine mismextensivelymmetabolizedmonmfirstmpassmthroughmthe m .m {{Ans-mLiver
Signsmandm symptomsmofmlithiummtoxicityminclude:m(selectmallmthatmapply)m {{Ans-mSlurredmspeech,mdrowsiness
Valproate macidmhasmFDA-approvedmindicationsmfor:m(selectmallmthatmapply)
{{Ans-mAcute mmania,msimple mandmcomplex mabsence mseizures,mpreventionmof mmigraine mheadaches
,Atomoxetine mselectivelym mthe m presynapticmreuptake mofmnorepinephrine mresultingminma(n)
m attention m span.
{{Ans-m Inhibits,mimproved
Phenelzine mdoesmnotmneedmtombemdiscontinuedmseveralmdaysmbefore melectivemsurgerymthatmrequiresman
esthesia.m{{Ans-mFalse
Bupropionmcanmbe m usedmformsmokingmcessation.m{{Ans-mTrue
Methylphenidate mismnotmeffective mformnarcolepticmpatients.m {{Ans-mFalse
Clozapine mmaymcause:m(selectmallmthatmapply) m {{Ans-mSyncope,morthostaticmhypotension, mcardiacmarrest
Causesmbradycardiamwhichmcouldmleadmtomsyncope mandmcardiacm arrest
Administeringmrisperidone mwithmlevodopamismcontraindicated.m {{Ans-mTrue
Itm decreasesmthe meffectsmof mlevodopa
The m m formm of mziprasidone mismfrequentlymusedmformcontrolmofmacutelymagitatedmpatients.
{{Ans-m Intramuscularm(IM)
Anticonvulsantsmare mfrequentlymusedmasmmoodmstabilizersmformthemtreatmentmofmmaniamandmbipolarmsp
ectrummdisordersmbecause mthey:m{{Ans-mReduce msynapticmkindling
Ampatientmwasmstartedmonmfluoxetinemformdepressionm3mdaysmago.mShe mnowmcomplainsmthatmitm"doesnm't
mhelp"m andm refusesm tom takem it.mUnderstandingm the mpsychopharmacology,m the mnurse'sm bestm firstm action
m ism to:
,{{Ans-
m Discuss m withmthem patientmthatmthesemtypesmof mmedications moftenmtakem severalmweeks mbefore mseeingm t
he mresults.
Whichmof mthe mfollowingmismamcommonmside meffectmofmbothmfirst-mandmsecond-
generationmantipsychoticmdrugs?m(selectmallmthatmapply)
{{Ans-mExtrapyramidalmside meffectsmsuchmasmpseudo-
parkinsonismmormacute mdystonia,mneurolepticmmalignantmsyndrome, mexcessive msedation
Ammale mpatientmwhomismtakingmthe msecond-
generationmantipsychoticmreportsmtomthemnursemthatmhem hasmobservedmamclearmfluidmleakingmfrommhismri
ghtmnipple mformthe mpastmmonth.mThe mnurse'smbestminitialminterventionmis:
{{Ans-mInformmthe mpatientmthatmthismcouldmbe mam side meffectmof mthe mmedication
The mphysicianmdiscussesmthe mappropriatenessmofmprescribingmamserotonin/norepinephrinemreuptake min
hibitorm(SNRI) mformampatient.mWhichmofmthe m followingmmedicationsmare minmthismcategory?
{{Ans-m Venlafaxine mandmduloxetine
Ampatientmhasmbeenmprescribedmamselective mserotoninmreuptakeminhibitorm(SSRI)mformdepression.mThe mn
urse mshouldmcounselmthe mpatientmaboutmwhichmofmthemfollowingmpossiblemsidemeffects,mamongmothers?
{{Ans-mFever,msweating,magitation,mrapidmheartbeat
Amnurse mcounselsmampatientmwhomhasmbeenmprescribedmammonoamine moxidaseminhibitorm(MAOI) mtomtre
atmdepressionmtomavoidmfoodsmcontainingmtyramine.mWhichmofmthemfollowingmfoodsmshouldmthe mpatient
m avoid?m (selectm allm thatm apply)
{{Ans-mYogurt,mtofu,mpepperoni
Ampatientmwithmseveremkidneymdiseasemismstartedmonmlithiummbymamnewmresident.mAsmthe mnurse monmdutymy
ourmbestminitialmresponse mwouldmbe mto:
{{Ans-
m Contactm the mresidentmtomremindmhimmthatmthem clientmhasmkidneym diseasemandmlithiummism contraindicat
ed
, Whichmof m the mfollowingmismgenerallymtrue mof mmedicationsmusedmtomtreatmanxietymdisorders?
{{Ans-
m Justm asmwithmdepression, mthemmostmcommonmmedications m prescribed marem serotonin m reuptake m inhibit
orsm(SSRIs) mandmselective mnorepinephrine mreuptake minhibitorsm(SNRIs).
Formwhichmonemof mthem followingmtypesmof mdrugsmismthe mconsumptionmof mgrapefruitmjuice mcontraindicated?
{{Ans-m Second-generationmantipsychotics
Psychopharmaceuticalmagentsmaremprescribedmformindividualsmwithmsubstancemusemdisordersmformallmofmthemfo
llowingmreasonsmexcept:
{{Ans-mTomelevate mthempatient'smmoodminmammannermcomparable mtomthe mactionmof m the mmisusedmsubstance
Ampatientmhasmbeenmprescribedmdisulfiram.mThe mnurse mwouldmmostmappropriatelymcounselmthe mpatientma
boutmwhichmof mthe mfollowing?
{{Ans-mAmtoxicmreactionmifmalcoholmismconsumed
Whenmampatientmismprescribedmrisperidonemformschizoaffective mdisorder,mthemnursemmustmalertmthempatie
ntmtomthe mpotentialmformneurolepticmmalignantmsyndrome.mWhichmof mthemfollowingmwouldmbemaccuratem
informationmtomgive mthe mpatient?
{{Ans-
m Neurolepticmmalignantmsyndrome m ism potentially m fatal.m Itmusuallym occursm duringm the mfirstm 2mweeksm afterm
startingmanm antipsychoticmdrugmormincreasingmthemdose mandmismcharacterizedmbymhighmfever,mmusclemstiff
ness,mparanoia,msweating,mandmlarge mchangesminmbloodmpressure.
Amclientmwithmdepressionmismtakingmphenelzine.mThe mnurse madvisesmthemclientmtomavoidmconsumingmwhic
hmfoodsmwhile mtakingmthe mmedicationm{{Ans-mYogurt
Methylphenidate mismamCNSmstimulantmandmismthe mdrugmof mchoice mformindividualsmwithmattention-
m deficit/hyperactivity m disorderm(ADHD). m The m desired m effects m of m methylphenidate m may m be m noted m as:
{{Ans-mIncreasedmattentionmspanmandmconcentration
