,NOTE TO INSTRUCTORS
Contact your Elsevier Sales Representative for teaching
resources, including slides and image banks, for Guyton and
Hall Textbook of Medical Physiology, 14e, or request these
supporting materials at:
http://evolve.elsevier.com/Hall/physiology/
, 14TH EDITION
Guyton and Hall
Textbook of Medical Physiology
John E. Hall, PhD
Arthur C. Guyton Professor and Chair
Department of Physiology and Biophysics
Director, Mississippi Center for Obesity Research
University of Mississippi Medical Center
Jackson, Mississippi
Michael E. Hall, MD, MS
Associate Professor
Department of Medicine, Division of
Cardiovascular Diseases
Associate Vice Chair for Research
Department of Physiology and Biophysics
University of Mississippi Medical Center
Jackson, Mississippi
, Elsevier
1600 John F. Kennedy Blvd.
Ste 1800
Philadelphia, PA 19103-2899
GUYTON AND HALL TEXTBOOK OF MEDICAL PHYSIOLOGY,
FOURTEENTH EDITION ISBN: 978-0-323-59712-8
INTERNATIONAL EDITION ISBN: 978-0-323-67280-1
Copyright © 2021 by Elsevier, Inc. All rights reserved.
No part of this publication may be reproduced or transmitted in any form or by any means, electronic or
mechanical, including photocopying, recording, or any information storage and retrieval system, without
permission in writing from the publisher. Details on how to seek permission, further information about the
Publisher’s permissions policies and our arrangements with organizations such as the Copyright Clearance
Center and the Copyright Licensing Agency, can be found at our website: www.elsevier.com/permissions.
This book and the individual contributions contained in it are protected under copyright by the Publisher
(other than as may be noted herein).
Notice
Practitioners and researchers must always rely on their own experience and knowledge in evaluating and
using any information, methods, compounds or experiments described herein. Because of rapid advances
in the medical sciences, in particular, independent verification of diagnoses and drug dosages should be
made. To the fullest extent of the law, no responsibility is assumed by Elsevier, authors, editors or
contributors for any injury and/or damage to persons or property as a matter of products liability,
negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas
contained in the material herein.
Previous editions copyrighted 2016, 2011, 2006, 2000, 1996, 1991, 1986, 1981, 1976, 1971, 1966, 1961, and 1956.
Library of Congress Control Number: 2020936245
Publisher: Elyse O’Grady
Senior Content Development Specialist: Jennifer Shreiner
Publishing Services Manager: Julie Eddy
Project Manager: Grace Onderlinde
Design Direction: Margaret Reid
Printed in Canada
Last digit is the print number: 9 8 7 6 5 4 3 2 1
Contact your Elsevier Sales Representative for teaching
resources, including slides and image banks, for Guyton and
Hall Textbook of Medical Physiology, 14e, or request these
supporting materials at:
http://evolve.elsevier.com/Hall/physiology/
, 14TH EDITION
Guyton and Hall
Textbook of Medical Physiology
John E. Hall, PhD
Arthur C. Guyton Professor and Chair
Department of Physiology and Biophysics
Director, Mississippi Center for Obesity Research
University of Mississippi Medical Center
Jackson, Mississippi
Michael E. Hall, MD, MS
Associate Professor
Department of Medicine, Division of
Cardiovascular Diseases
Associate Vice Chair for Research
Department of Physiology and Biophysics
University of Mississippi Medical Center
Jackson, Mississippi
, Elsevier
1600 John F. Kennedy Blvd.
Ste 1800
Philadelphia, PA 19103-2899
GUYTON AND HALL TEXTBOOK OF MEDICAL PHYSIOLOGY,
FOURTEENTH EDITION ISBN: 978-0-323-59712-8
INTERNATIONAL EDITION ISBN: 978-0-323-67280-1
Copyright © 2021 by Elsevier, Inc. All rights reserved.
No part of this publication may be reproduced or transmitted in any form or by any means, electronic or
mechanical, including photocopying, recording, or any information storage and retrieval system, without
permission in writing from the publisher. Details on how to seek permission, further information about the
Publisher’s permissions policies and our arrangements with organizations such as the Copyright Clearance
Center and the Copyright Licensing Agency, can be found at our website: www.elsevier.com/permissions.
This book and the individual contributions contained in it are protected under copyright by the Publisher
(other than as may be noted herein).
Notice
Practitioners and researchers must always rely on their own experience and knowledge in evaluating and
using any information, methods, compounds or experiments described herein. Because of rapid advances
in the medical sciences, in particular, independent verification of diagnoses and drug dosages should be
made. To the fullest extent of the law, no responsibility is assumed by Elsevier, authors, editors or
contributors for any injury and/or damage to persons or property as a matter of products liability,
negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas
contained in the material herein.
Previous editions copyrighted 2016, 2011, 2006, 2000, 1996, 1991, 1986, 1981, 1976, 1971, 1966, 1961, and 1956.
Library of Congress Control Number: 2020936245
Publisher: Elyse O’Grady
Senior Content Development Specialist: Jennifer Shreiner
Publishing Services Manager: Julie Eddy
Project Manager: Grace Onderlinde
Design Direction: Margaret Reid
Printed in Canada
Last digit is the print number: 9 8 7 6 5 4 3 2 1
