NS 3410 Review: Iron Metabolism and Cell Transport Questions With Complete Solutions

NS 3410 Review: Iron Metabolism and Cell
Transport Questions With Complete Solutions


Ferric
Fe3+
Ferrous
Fe2+
DMT1
Transporter that moves ferrous iron (Fe2+) across
the apical membrane.

,Ferroportin
Transporter that moves iron across the basolateral
membrane.
Ferritin
Protein that binds iron for intracellular storage.
dcytb
Ferric reductase that reduces ferric iron (Fe3+) to
ferrous iron (Fe2+).
Ferroxidase

, Enzyme that oxidizes ferrous iron (Fe2+) to ferric
iron (Fe3+) for transport in plasma.
Transferrin Cycle
Process by which ferric iron circulates bound to
transferrin and is taken up by cells.
Atransferrinemia
Condition characterized by lack of transferrin and
inability to transfer iron into erythroid tissue.
Erythropoietin (EPO)
Hormone made in the kidney that regulates RBC
synthesis.
Erythroferrone
Hormone made in bone and spleen that inhibits
hepcidin.
Hepcidin
Master regulator hormone made in the liver that
prevents iron absorption and blocks iron release
from stores.
Anterior
Front of the body (ventral).
Posterior
Back of the body (dorsal).
Superior