PATH 3610 UNIT 4: TEST
QUESTIONS WITH COMPLETE
SOLUTIONS
Sites of lymphocyte priming are the: -- Answer ✔✔ thymus and bone
marrow
Amplification or expansion of the immune response is characteristic of:
-- Answer ✔✔ the B cell response to antigen and the T cell response to
antigen
The term serology refers to the study of: -- Answer ✔✔ antigen-
antibody reactions in a laboratory setting
Human newborns receive passively acquired antibody from their
mothers, which is primarily obtained by: -- Answer ✔✔ transplacental
passage
During the lag period of the primary immune response, B cells with
receptors for the specific antigen: -- Answer ✔✔ undergo clonal
expansion to produce a large number of plasma cells
,The specificity of T cells is determined by: -- Answer ✔✔ the T cell
receptor
Type IV (cell-mediated) hypersensitivity is mediated by: -- Answer ✔✔
sensitized T cells
The end result of immune-complex mediated hypersensitivity is: --
Answer ✔✔ fibrinoid necrosis of small vessels (necrotizing vasculitis)
Cells which play a key role in the early stages of the immune response
are the: -- Answer ✔✔ macrophages
Cell mediated immunity is an important function of: -- Answer ✔✔
cytotoxic T cells
Plasma cells secrete: -- Answer ✔✔ antibody
In the secondary immune response: -- Answer ✔✔ specific antibody
production occurs more rapidly
Macrophages and monocytes act as important reservoirs and
producers of HIV. T/F -- Answer ✔✔ True
Natural killer cells are: -- Answer ✔✔ lymphocytes able to kill a variety
of cells without prior sensitization
, Lymph nodes which are enlarged because of response to an antigenic
stimulus are termed: -- Answer ✔✔ reactive
Molecules which evoke an immune response when introduced into a
host are termed: -- Answer ✔✔ Antigens
Cross-linking of numbers of antibody and antigen units leads to: --
Answer ✔✔ agglutination
Nonspecific defense mechanisms: -- Answer ✔✔ include all defense
mechanisms other than the immune response
The similarity between donor and recipient with regard to
histocompatibility antigens is a major determinant of the success of
tissue and organ transplants. T/F -- Answer ✔✔ True
In Type II (antibody-dependent) hypersensitivity, antibody is directed
against: -- Answer ✔✔ specific antigens on cell surfaces
Immune complex formation may cause: -- Answer ✔✔ complement
activation
T cells are characterized by: -- Answer ✔✔ surface receptors which
determine their specificity
QUESTIONS WITH COMPLETE
SOLUTIONS
Sites of lymphocyte priming are the: -- Answer ✔✔ thymus and bone
marrow
Amplification or expansion of the immune response is characteristic of:
-- Answer ✔✔ the B cell response to antigen and the T cell response to
antigen
The term serology refers to the study of: -- Answer ✔✔ antigen-
antibody reactions in a laboratory setting
Human newborns receive passively acquired antibody from their
mothers, which is primarily obtained by: -- Answer ✔✔ transplacental
passage
During the lag period of the primary immune response, B cells with
receptors for the specific antigen: -- Answer ✔✔ undergo clonal
expansion to produce a large number of plasma cells
,The specificity of T cells is determined by: -- Answer ✔✔ the T cell
receptor
Type IV (cell-mediated) hypersensitivity is mediated by: -- Answer ✔✔
sensitized T cells
The end result of immune-complex mediated hypersensitivity is: --
Answer ✔✔ fibrinoid necrosis of small vessels (necrotizing vasculitis)
Cells which play a key role in the early stages of the immune response
are the: -- Answer ✔✔ macrophages
Cell mediated immunity is an important function of: -- Answer ✔✔
cytotoxic T cells
Plasma cells secrete: -- Answer ✔✔ antibody
In the secondary immune response: -- Answer ✔✔ specific antibody
production occurs more rapidly
Macrophages and monocytes act as important reservoirs and
producers of HIV. T/F -- Answer ✔✔ True
Natural killer cells are: -- Answer ✔✔ lymphocytes able to kill a variety
of cells without prior sensitization
, Lymph nodes which are enlarged because of response to an antigenic
stimulus are termed: -- Answer ✔✔ reactive
Molecules which evoke an immune response when introduced into a
host are termed: -- Answer ✔✔ Antigens
Cross-linking of numbers of antibody and antigen units leads to: --
Answer ✔✔ agglutination
Nonspecific defense mechanisms: -- Answer ✔✔ include all defense
mechanisms other than the immune response
The similarity between donor and recipient with regard to
histocompatibility antigens is a major determinant of the success of
tissue and organ transplants. T/F -- Answer ✔✔ True
In Type II (antibody-dependent) hypersensitivity, antibody is directed
against: -- Answer ✔✔ specific antigens on cell surfaces
Immune complex formation may cause: -- Answer ✔✔ complement
activation
T cells are characterized by: -- Answer ✔✔ surface receptors which
determine their specificity
