PATH 3610 FINAL EXAM REVIEW
QUESTIONS WITH ACCURATE
SOLUTIONS
1) Death of cells in a living organism is termed:
1. Gangrene
2. Necrosis
3. Ischemia -- Correct Answer ✔✔ Necrosis
2) Apoptosis refers to:
1. The internalization of material by a cell
2. Disintegration of tissues which occurs after death
3. Programmed cell death -- Correct Answer ✔✔ Programmed cell
death
3) A myocardial infarct is seen as a dry, well demarcated area of pale
tissue. This would be described as:
1. Coagulation necrosis
2. Caseation necrosis
3. An abscess -- Correct Answer ✔✔ Coagulation necrosis
,4) Free radicals can impair cell membrane function by causing:
1. Lesions in DNA
2. Lipid peroxidation
3. Protein cross-linking -- Correct Answer ✔✔ Lipid peroxidation
5) Starvation can lead to the development of fatty liver.
True or false? -- Correct Answer ✔✔ True
6) Regional tissue necrosis due to ischemia, followed by secondary
bacterial infection defines:
1. Autolysis
2. Putrefaction
3. Gangrene -- Correct Answer ✔✔ Gangrene
7) Hypoxia, leading to impaired energy production by the cell, may be
caused by:
1. Anemia
2. Low blood glucose levels
3. Inhibition of respiratory enzymes -- Correct Answer ✔✔ Anemia
,8) The primary change in hemolytic jaundice is:
1. Inadequate bilirubin excretion
2. Increased production of bilirubin
3. Serum accumulation of conjugated bilirubin -- Correct Answer
✔✔ Increased production of bilirubin
9) Bilirubin is:
1. Lipid soluble when conjugated
2. Water soluble when conjugated
3. Conjugated in the kidney for excretion in the urine -- Correct
Answer ✔✔ Water soluble when conjugated
10) Cellular injury can result when bilirubin accumulates in:
1. Parenchymal cells (such as the liver or brain)
2. Connective tissue
3. Skin -- Correct Answer ✔✔ Parenchymal cells (such as the liver
or brain)
11) Anemia will lead to impaired energy production by the cell
because there is:
1. Insufficient oxygen
2. Low glucose levels
3. Enzyme inhibition -- Correct Answer ✔✔ Insufficient oxygen
, 12) Ischemia refers to:
1. A reduction of failure of blood supply to tissues
2. The death of tissues due to inadequate blood supply
3. Insufficient oxygenation of tissues due to poor blood supply --
Correct Answer ✔✔ A reduction of failure of blood supply to
tissues
13) With vascular injury, platelets are exposed to the extracellular
matrix, which induces platelet adhesion via interaction with:
1. von Willebrand factor
2. Thromboxane
3. ADP -- Correct Answer ✔✔ von Willebrand factor
14) The "economy class syndrome" occurs with prolonged air travel
in cramped seating. The described thrombosis occurs because there
is:
1. Increased viscosity of blood due to poor oxygenation
2. Increased turbulence of blood flow
3. Stasis of blood flow in veins of the legs -- Correct Answer ✔✔
Stasis of blood flow in veins of the legs
15) Transient arteriolar vasoconstriction in early hemostasis is
primarily due to:
QUESTIONS WITH ACCURATE
SOLUTIONS
1) Death of cells in a living organism is termed:
1. Gangrene
2. Necrosis
3. Ischemia -- Correct Answer ✔✔ Necrosis
2) Apoptosis refers to:
1. The internalization of material by a cell
2. Disintegration of tissues which occurs after death
3. Programmed cell death -- Correct Answer ✔✔ Programmed cell
death
3) A myocardial infarct is seen as a dry, well demarcated area of pale
tissue. This would be described as:
1. Coagulation necrosis
2. Caseation necrosis
3. An abscess -- Correct Answer ✔✔ Coagulation necrosis
,4) Free radicals can impair cell membrane function by causing:
1. Lesions in DNA
2. Lipid peroxidation
3. Protein cross-linking -- Correct Answer ✔✔ Lipid peroxidation
5) Starvation can lead to the development of fatty liver.
True or false? -- Correct Answer ✔✔ True
6) Regional tissue necrosis due to ischemia, followed by secondary
bacterial infection defines:
1. Autolysis
2. Putrefaction
3. Gangrene -- Correct Answer ✔✔ Gangrene
7) Hypoxia, leading to impaired energy production by the cell, may be
caused by:
1. Anemia
2. Low blood glucose levels
3. Inhibition of respiratory enzymes -- Correct Answer ✔✔ Anemia
,8) The primary change in hemolytic jaundice is:
1. Inadequate bilirubin excretion
2. Increased production of bilirubin
3. Serum accumulation of conjugated bilirubin -- Correct Answer
✔✔ Increased production of bilirubin
9) Bilirubin is:
1. Lipid soluble when conjugated
2. Water soluble when conjugated
3. Conjugated in the kidney for excretion in the urine -- Correct
Answer ✔✔ Water soluble when conjugated
10) Cellular injury can result when bilirubin accumulates in:
1. Parenchymal cells (such as the liver or brain)
2. Connective tissue
3. Skin -- Correct Answer ✔✔ Parenchymal cells (such as the liver
or brain)
11) Anemia will lead to impaired energy production by the cell
because there is:
1. Insufficient oxygen
2. Low glucose levels
3. Enzyme inhibition -- Correct Answer ✔✔ Insufficient oxygen
, 12) Ischemia refers to:
1. A reduction of failure of blood supply to tissues
2. The death of tissues due to inadequate blood supply
3. Insufficient oxygenation of tissues due to poor blood supply --
Correct Answer ✔✔ A reduction of failure of blood supply to
tissues
13) With vascular injury, platelets are exposed to the extracellular
matrix, which induces platelet adhesion via interaction with:
1. von Willebrand factor
2. Thromboxane
3. ADP -- Correct Answer ✔✔ von Willebrand factor
14) The "economy class syndrome" occurs with prolonged air travel
in cramped seating. The described thrombosis occurs because there
is:
1. Increased viscosity of blood due to poor oxygenation
2. Increased turbulence of blood flow
3. Stasis of blood flow in veins of the legs -- Correct Answer ✔✔
Stasis of blood flow in veins of the legs
15) Transient arteriolar vasoconstriction in early hemostasis is
primarily due to:
