well answered already passed
1. gastric or duodenal ulcers that involve digestions of peptic ulcer
disease PUD
the GI mucosa by the enzyme pepsin
2. What are the types of acid-controlling drugs? antacids
H2 antagonists
proton pump inhibitors
3. bacterium found in the GI tract of 90% of helicobacter pylori (H.pylori)
patients w/duodenal ulcers and 70% of
patients w/gastric ul- cers:
4. What is the first line therapy for H.pylori? treated with a proton pump
inhibitor PPI and antibiotics
5. GI lesions; and calcium
decreased
bloodflow; 8. basic
mucosal compounds
ischemia; used to
hyperfusion; neutralize
reperfusion injury stomach
can be caused by NG tube and/or ventilators acid;
contain
6. Many antacid medications also contain the salts of
antiflat- uent drug . aluminum,
magnesium
7. Many aluminum and calcium based antacid , calcium
formu- lations also include and/or
which contributes to the sodium
acid neutralizing capacity and also
counteracts the effects of aluminum
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,Pharmacology exam 4 Ch 32, 45, 46, 50 Nur138 ECPI
well answered already passed
Stress-related mucosal damage
magnesium; constipating
simethicone antacids
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,Pharmacology exam 4 Ch 32, 45, 46, 50 Nur138 ECPI
well answered already passed
9. calcium antacids may lead to the kidney stones
development of
and increased gastric acid secretions.
magnesium
10. Patients with renal failure must avoid
calcium
antacids con- taining what?
sodium bicarbonate
11. What is a highly soluble antacid form with a
quick onset, but a short duration of
action?
12. What are the MOA for antacids? neutralize acid
secretions; promote
gastric mucosal
defense mechanism;
stimulate secretions
of: mucus: protective
barrier against HCI
bicarbonate: butter acidic
properties of HCI
prostaglandins: prevent ac
tivation of proton pump
13. What do antacids NOT do? prevent the
overproduction of acid
14. What are contraindications for antacid use? known allergy;
renal failure;
electrolyte
disturbances; GI
obstruction
15. have a constipating effect; often
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,Pharmacology exam 4 Ch 32, 45, 46, 50 Nur138 ECPI
well answered already passed
recommended for patients w/renal aluminum salts
failure (easily excreted)
16. magnesium salts
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